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ChemicalBook CAS DataBase List NIH-12848
959551-10-1

NIH-12848 synthesis

5synthesis methods
27757-85-3 Synthesis
2-Thiophenemethylamine

27757-85-3
260 suppliers
$6.00/1g

-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: triethylamine / dichloromethane / 18 h / 20 °C
2: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / water; acetonitrile / 10 h / 150 °C / Microwave irradiation

References:

Dexheimer, Thomas S.;Rosenthal, Andrew S.;Luci, Diane K.;Liang, Qin;Villamil, Mark A.;Chen, Junjun;Sun, Hongmao;Kerns, Edward H.;Simeonov, Anton;Jadhav, Ajit;Zhuang, Zhihao;Maloney, David J. [Journal of Medicinal Chemistry,2014,vol. 57,# 19,p. 8099 - 8110]