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DFMO

DFMO Structure
DFMO structure
CAS No.
66640-93-5
Chemical Name:
DFMO
Synonyms
DFMO;L-DFMO;L-RMI71782;EFLORNITINE;L-Eflornithine;H-DL-(F2ME)ORN-OH;DIFLUOROMETHYLORNITHINE;L-α-difluoromethylornithine;L-α-difluoromethylornithine;L Eflornithine,LEflornithine
CBNumber:
CB1373228
Molecular Formula:
C6H12F2N2O2
Molecular Weight:
182.17
MDL Number:
MFCD00221766
MOL File:
66640-93-5.mol
Last updated:2023-05-21 10:59:17
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DFMO Properties

Boiling point 347.0±42.0 °C(Predicted)
Density 1.293±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 1.22±0.44(Predicted)
NCI Dictionary of Cancer Terms difluoromethylornithine
FDA UNII C780YUS9YI

DFMO price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AHH MT-50140 Difluoromethylornithine 98% 66640-93-5 1g $310 2021-12-16 Buy
Product number Packaging Price Buy
MT-50140 1g $310 Buy

DFMO Chemical Properties,Uses,Production

Biological Activity

L-Eflornithine (L-DFMO) is the enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with KD of 1.3±0.3 μM and Kinact of 0.15±0.03 min-1.

in vivo

The more potent L-Eflornithine is present at much lower concentrations in both plasma and cerebrospinal fluid (CSF) than those of the D-Eflornithine. The plasma concentrations of L-Eflornithine are on average 52% of the D -enantiomer concentrations. The typical oral clearances of L-Eflornithine and D-eflornithine are 17.4 and 8.23 liters/h, respectively.

target

KD: 1.3±0.3 μM (Ornithine decarboxylase, ODC)

DFMO Preparation Products And Raw materials

Raw materials

Preparation Products

DFMO Suppliers

Global( 12)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Sanover (Xiamen) Technology Co., Ltd 059265188632; 13876246362 422165847@qq.com China 509 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Sanover (Xiamen) Technology Co., Ltd 58
TargetMol Chemicals Inc. 58

66640-93-5(DFMO)Related Search:

BETA-FLUORO-DL-ALANINE 2-(TRIFLUOROMETHYL)ORNITHINE DFMO Eflornithine hydrochloride DFMO
ALPHA-DIFLUORO-ME-DL-ORNITHINE ALPHA-DIFLUOROMETHYL-DL-ORNITHINE L-alpha-Difluoromethylornithine DFMO EFLORNITINE DL-ALPHA-DIFLUOROMETHYLORNITHINE DIFLUOROMETHYLORNITHINE H-DL-(F2ME)ORN-OH H-DL-(ALPHA-DIFLUOROMETHYL)ORN-OH H-ALPHA-DIFLUORO-ME-DL-ORN-OH L-Eflornithine L-α-difluoromethylornithine L-Ornithine, 2-(difluoromethyl)- L-α-difluoromethylornithine L-RMI71782 L-DFMO L Eflornithine,LEflornithine 66640-93-5 Angiogenesis BioChemical Cancer Research Angiogenesis Inhibitors