ChemicalBook >> CAS DataBase List >>4,6-DIOXOHEPTANOIC ACID
4,6-DIOXOHEPTANOIC ACID
- CAS No.
- 51568-18-4
- Chemical Name:
- 4,6-DIOXOHEPTANOIC ACID
- Synonyms
- SUCCINYLACETONE;4,6-dioxoheptanoicaci;[13C7]-Succinylacetone;4,6-DIOXOHEPTANOIC ACID;Heptanoic acid, 4,6-dioxo-;Succinylacetone-3,4,5,6,7-13C5;4,6-Dioxoheptanoic acid-3,4,5,6,7-13C5;4,6-Dioxoheptanoic acid (mixture of isomers)
- CBNumber:
- CB1385063
- Molecular Formula:
- C7H10O4
- Molecular Weight:
- 158.15
- MDL Number:
- MFCD00002797
- MOL File:
- 51568-18-4.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:11
Melting point | 66-67 °C(lit.) |
---|---|
Boiling point | 318.7±17.0 °C(Predicted) |
Density | 1.189±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
pka | 4.54±0.17(Predicted) |
form | powder |
color | White to Off-White |
CAS DataBase Reference | 51568-18-4 |
FDA UNII | KZ0KV2Q190 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36 |
WGK Germany | 3 |
4,6-DIOXOHEPTANOIC ACID price More Price(21)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | D1415 | 4,6-Dioxoheptanoic acid powder | 51568-18-4 | 100mg | $313 | 2024-03-01 | Buy |
Sigma-Aldrich | D1415 | 4,6-Dioxoheptanoic acid powder | 51568-18-4 | 1g | $1790 | 2024-03-01 | Buy |
TCI Chemical | U0127 | Succinylacetone | 51568-18-4 | 100MG | $234 | 2023-01-07 | Buy |
TCI Chemical | U0127 | Succinylacetone | 51568-18-4 | 25MG | $79 | 2022-04-27 | Buy |
Cayman Chemical | 25501 | Succinylacetone ≥98% | 51568-18-4 | 10mg | $32 | 2024-03-01 | Buy |
4,6-DIOXOHEPTANOIC ACID Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
4,6-Dioxoheptanoic acid has been used:
- as component of dendritic cell conditioning medium and in the inhibition of ALA dehydratase (ALAD) in dendritic cells(50)
- as an inhibitor of heme biosynthesis in human mononuclear cells(51) and HeLa cells(52)
- as a standard for the quantification of succinylacetone from Plasmodium falciparum cultures(53)
Uses
Succinylacetone (SA) is a specific marker for the inherited metabolic disease, hepatorenal tyrosinemia. It was developed a stable-isotope quid urine using a 13C4-SA as internal standard.
Definition
ChEBI: A dioxo monocarboxylic acid that is heptanoic acid in which oxo groups replace the hydrogens at positions 4 and 6. It is an abnormal metabolite of the tyrosine metabolic pathway and a marker for type 1 tyrosinaemia.
Biochem/physiol Actions
4,6-Dioxoheptanoic acid is an inhibitor of heme biosynthesis. It is a catabolic byproduct of tyrosine breakdown and inhibits δ-aminolevulinic acid (ALA) dehydratase enzyme. It is a potential marker for detecting tyrosinemia type I and is measured in dried blood spot of new borns.
4,6-DIOXOHEPTANOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 112)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18628 | 58 |
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd. | 0431-80514535 13634302652 | Extension@chemextension.com | CHINA | 967 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
Shanghai Daeyeon Chemicals Co., Ltd | 021-64478606 +8615900664856 | daeyeon001@vip.163.com | China | 2062 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30250 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52861 | 58 |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
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4,6-DIOXOHEPTANOIC ACID
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SUCCINYLACETONE
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4,6-dioxoheptanoicaci
[13C7]-Succinylacetone
4,6-Dioxoheptanoic acid (mixture of isomers)
51568-18-4
CH3COCH2COCH2CH2CO2H
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BioChemical
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