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4,6-DIOXOHEPTANOIC ACID

4,6-DIOXOHEPTANOIC ACID structure

CAS No.: 51568-18-4

Chemical Name:: 4,6-DIOXOHEPTANOIC ACID

Synonyms: SUCCINYLACETONE;4,6-dioxoheptanoicaci;[13C7]-Succinylacetone;4,6-DIOXOHEPTANOIC ACID;Heptanoic acid, 4,6-dioxo-;Succinylacetone-3,4,5,6,7-13C5;4,6-Dioxoheptanoic acid-3,4,5,6,7-13C5;4,6-Dioxoheptanoic acid (mixture of isomers)

CBNumber:: CB1385063

Molecular Formula:: C7H10O4

Molecular Weight:: 158.15

MDL Number:: MFCD00002797

MOL File:: 51568-18-4.mol

MSDS File:: SDS

Last updated:2023-05-18 11:31:11

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4,6-DIOXOHEPTANOIC ACID Properties

Melting point	66-67 °C(lit.)
Boiling point	318.7±17.0 °C(Predicted)
Density	1.189±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka	4.54±0.17(Predicted)
form	powder
color	White to Off-White
CAS DataBase Reference	51568-18-4
FDA UNII	KZ0KV2Q190

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3

4,6-DIOXOHEPTANOIC ACID price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	D1415	4,6-Dioxoheptanoic acid powder	51568-18-4	100mg	$313	2024-03-01	Buy
Sigma-Aldrich	D1415	4,6-Dioxoheptanoic acid powder	51568-18-4	1g	$1790	2024-03-01	Buy
TCI Chemical	U0127	Succinylacetone	51568-18-4	100MG	$234	2023-01-07	Buy
TCI Chemical	U0127	Succinylacetone	51568-18-4	25MG	$79	2022-04-27	Buy
Cayman Chemical	25501	Succinylacetone ≥98%	51568-18-4	10mg	$32	2024-03-01	Buy

Product number	Packaging	Price	Buy
D1415	100mg	$313	Buy
D1415	1g	$1790	Buy
U0127	100MG	$234	Buy
U0127	25MG	$79	Buy
25501	10mg	$32	Buy

4,6-DIOXOHEPTANOIC ACID Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

4,6-Dioxoheptanoic acid has been used:

as component of dendritic cell conditioning medium and in the inhibition of ALA dehydratase (ALAD) in dendritic cells(50)
as an inhibitor of heme biosynthesis in human mononuclear cells(51) and HeLa cells(52)
as a standard for the quantification of succinylacetone from Plasmodium falciparum cultures(53)

Uses

Succinylacetone (SA) is a specific marker for the inherited metabolic disease, hepatorenal tyrosinemia. It was developed a stable-isotope quid urine using a 13C4-SA as internal standard.

Definition

ChEBI: A dioxo monocarboxylic acid that is heptanoic acid in which oxo groups replace the hydrogens at positions 4 and 6. It is an abnormal metabolite of the tyrosine metabolic pathway and a marker for type 1 tyrosinaemia.

Biochem/physiol Actions

4,6-Dioxoheptanoic acid is an inhibitor of heme biosynthesis. It is a catabolic byproduct of tyrosine breakdown and inhibits δ-aminolevulinic acid (ALA) dehydratase enzyme. It is a potential marker for detecting tyrosinemia type I and is measured in dried blood spot of new borns.

4,6-DIOXOHEPTANOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

4,6-DIOXOHEPTANOIC ACID Suppliers

Global( 106)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15932	58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd.	0431-80514535 13634302652	Extension@chemextension.com	CHINA	967	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
Shanghai Daeyeon Chemicals Co., Ltd	021-64478606 +8615900664856	daeyeon001@vip.163.com	China	2062	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	CHINA	52867	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58

Supplier	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd.	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Shanghai Daeyeon Chemicals Co., Ltd	58
Career Henan Chemica Co	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Nextpeptide Inc	58

4,6-DIOXOHEPTANOIC ACID Spectrum

4,6-DIOXOHEPTANOIC ACID(51568-18-4)¹HNMR 4,6-DIOXOHEPTANOIC ACID(51568-18-4)IR 4,6-DIOXOHEPTANOIC ACID(51568-18-4)Raman

51568-18-4(4,6-DIOXOHEPTANOIC ACID)Related Search:

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7-(5-METHYLTHIEN-2-YL)-4,7-DIOXOHEPTANOIC ACID BIS-2,2-SUCCINOYLMETHYLENE-PROPIONIC ACID CHOLESTERYL ESTER 3-(1,2,3,4-Tetrahydro-6-methoxy-1-oxo-2-naphthoyl)propionicacid

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4,6-DIOXOHEPTANOIC ACID Succinylacetone-3,4,5,6,7-13C5 4,6-Dioxoheptanoic acid-3,4,5,6,7-13C5 SUCCINYLACETONE Heptanoic acid, 4,6-dioxo- 4,6-dioxoheptanoicaci [13C7]-Succinylacetone 4,6-Dioxoheptanoic acid (mixture of isomers) 51568-18-4 CH3COCH2COCH2CH2CO2H Biochemicals and Reagents BioChemical Saturated fatty acids and derivatives Lipids Keto fatty acids Fatty Acids Aliphatics Intermediates & Fine Chemicals Pharmaceuticals