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The intermediate of Vitamin E Chemical Properties Uses Production method
Trimethylhydroquinone structure
Chemical Name:
tmhq;-Cumoquinol;psi-Cumohydroquinone;TRIMETHYLHYDROQUINONE;Trimethylhydroqninone;2,3,5-Trimethylquinol;trimethyl-hydroquinon;Pseudocumohydroquinone;3,6-dihydroxypseudocumol;Hydroquinone, trimethyl-
Molecular Formula:
Formula Weight:
MOL File:

Trimethylhydroquinone Properties

Melting point:
169-172 °C(lit.)
Boiling point:
295 °C (759.8513 mmHg)
0.9595 (rough estimate)
refractive index 
1.4464 (estimate)
Flash point:
191 °C
methanol: 0.1 g/mL, clear
Crystalline Powder
Water Solubility 
2 g/L (20 ºC)
Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference
700-13-0(CAS DataBase Reference)
NIST Chemistry Reference
EPA Substance Registry System
1,4-Benzenediol, 2,3,5-trimethyl-(700-13-0)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn,N
Risk Statements  20-37/38-41-43-50/53
Safety Statements  24-26-37/39-60-61
RIDADR  UN 3077 9/PG 3
WGK Germany  2
RTECS  MX7820000
HazardClass  9
PackingGroup  III
HS Code  29072990
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning P273, P391, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P314 Get medical advice/attention if you feel unwell.
P391 Collect spillage. Hazardous to the aquatic environment
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to..…

Trimethylhydroquinone price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T76503 Trimethylhydroquinone 97% 700-13-0 100g $47.2 2018-11-13 Buy
Sigma-Aldrich T76503 Trimethylhydroquinone 97% 700-13-0 500g $182 2018-11-13 Buy
TCI Chemical T0477 Trimethylhydroquinone >98.0%(GC)(T) 700-13-0 25g $28 2018-11-22 Buy
TCI Chemical T0477 Trimethylhydroquinone >98.0%(GC)(T) 700-13-0 100g $79 2018-11-22 Buy
Alfa Aesar B22819 Trimethylhydroquinone, 98% 700-13-0 500g $160 2018-11-13 Buy

Trimethylhydroquinone Chemical Properties,Uses,Production

The intermediate of Vitamin E

Trimethylhydroquinone and isophytol are two intermediate in the synthesis of vitamin E, currently trimethylhydroquinone in world market is mainly produced by BASF and Roche, it can not meet the needs of vitamin E. The 2,3,5-trimethyl hydroquinone of China is put into operation by only a few companies, China has become the world's second largest feed production country, if the amount of vitamin E in animal feed reach the average level of foreign words, the annual consumption vitamin E is nearly 2000t. According to Chinese feed industry planning, the amount of feed demand synthetic vitamin E is about 2500t in 2005. Furthermore, the needs of vitamin E in pharmaceutical, food, cosmetics and other needs for vitamin E will grow steadily in the future. So in the last ten years, or even 20 years, the future market 2,3,5-trimethyl hydroquinone can not be not saturated. The development of this project has broad application prospects.
Vitamin E is not only used as a medicine, feed, food, cosmetic additives, but also get more and more applications in industry, such as industrial antioxidants, polyolefin non-toxic, biodegradable stabilizer. A sharp increase in domestic and international market demand for vitamin E is present. The naturally occurring vitamin E is very limited, so timely start-up and expansion of production of vitamin E will bring better economic benefits.
The above information is edited by the chemicalbook of Wang Xiaodong.

Chemical Properties

It is crystalline solid. When heated, it can sublimate, when esposed to moisture, it can turn black easily. It can be slightly soluble in water, soluble in ethyl alcohol, insoluble in petroleum ether. Melting point is 173℃.


The product is main ring of vitamin E, it can condensation with isophytol to get vitamin E.
Organic intermediates, pharmaceutical intermediates, it can be used for the synthesis of VE.

Production method

By sulfonation, nitration, reduction, oxidation 1,2,4-trimethylbenzene can get 2,3,5-trimethyl benzoquionone ([935-92-2]). 2,3,5-trimethyl benzoquionone is yellow needle crystallization, melting point is 32℃ (38-29.5℃), the boiling point is 53℃(53Pa). Said step of products are generally to obtain a solution of petroleum ether or gasoline. In 2,3,5-trimethyl gasoline solution (petroleum ether), hydrosulfite solution is added with stirring, stir at room temperature for 3h, then filter, the cake should be washed with 0.5% hydrosulfite solution, and then dry to get trimethyl hydroquinone.

Chemical Properties

off-white, tan or orange powder

Safety Profile

Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes.

Purification Methods

Recrystallise the hydroquinone from water, under anaerobic conditions. [Beilstein 6 H 931, 6 IV 5997.]

Trimethylhydroquinone Preparation Products And Raw materials

Raw materials

Preparation Products

Trimethylhydroquinone Suppliers

Global( 190)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Tianjin Zhongxin Chemtech Co., Ltd.
022-66880086 CHINA 559 58
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 China 19954 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 22043 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20786 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 CHINA 1374 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32651 55
Qingdao Hongjin Trading Co., Ltd.
0532-83657313 CHINA 225 58
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 24118 58
Haihang Industry Co.,Ltd
+86 531 8582 1093 CHINA 4525 58
career henan chemical co
+86-371-86658258 CHINA 19997 58

View Lastest Price from Trimethylhydroquinone manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-17 Trimethylhydroquinone
US $1.00 / KG 1G 98% 100KG career henan chemical co

Trimethylhydroquinone Spectrum

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