5-Bromo-4-chloro-2-methylsulfanyl-pyrimidine
- CAS No.
- 63810-78-6
- Chemical Name:
- 5-Bromo-4-chloro-2-methylsulfanyl-pyrimidine
- Synonyms
- 5-Bromo-4-chloro-2-(methylthio)pyrimidine;5-Bromo-4-chloro-2-(methy...;Pyrimidine, 5-bromo-4-chloro-2-(methylthio)-;5-Bromo-4-chloro-2-methylsulfanyl-pyrimidine;5-Bromo-4-chloro-2-(methylthio)pyrimidine >5-Bromo-4-chloro-2-(methylthio)pyrimidine ,97%;5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE ISO 9001：2015 REACH
- CBNumber:
- CB1663121
- Molecular Formula:
- C5H4BrClN2S
- Molecular Weight:
- 239.52
- MDL Number:
- MFCD00023232
- MOL File:
- 63810-78-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 45.0 to 49.0 °C |
|---|---|
| Boiling point | 309.5±22.0 °C(Predicted) |
| Density | 1.83±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | -1.97±0.29(Predicted) |
| color | White to Almost white |
| InChI | InChI=1S/C5H4BrClN2S/c1-10-5-8-2-3(6)4(7)9-5/h2H,1H3 |
| InChIKey | XVRYJQACDDVZEI-UHFFFAOYSA-N |
| SMILES | C1(SC)=NC=C(Br)C(Cl)=N1 |
| CAS DataBase Reference | 63810-78-6 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P405-P501 | |||||||||
| Risk Statements | 34-22 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | 2923 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | Ⅲ | |||||||||
| HS Code | 29335990 | |||||||||
| Limited Quantities | 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
5-Bromo-4-chloro-2-methylsulfanyl-pyrimidine price More Price(64)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S445827 | 5-BROMO-4-CHLORO-2-METHYLTHIOPYRIMIDINE AldrichCPR | 63810-78-6 | 1 unit | $32.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | S445827 | 5-BROMO-4-CHLORO-2-METHYLTHIOPYRIMIDINE Aldrich | 63810-78-6 | 50mg | $29.8 | 2024-03-01 | Buy |
| TCI Chemical | B4406 | 5-Bromo-4-chloro-2-(methylthio)pyrimidine >98.0%(GC) | 63810-78-6 | 1g | $43 | 2026-04-30 | Buy |
| TCI Chemical | B4406 | 5-Bromo-4-chloro-2-(methylthio)pyrimidine min. 98.0 % | 63810-78-6 | 5G | $130 | 2026-04-30 | Buy |
| Apolloscientific | OR345386 | 5-Bromo-4-chloro-2-(methylthio)pyrimidine >99% | 63810-78-6 | 250mg | $21 | 2026-06-04 | Buy |
5-Bromo-4-chloro-2-methylsulfanyl-pyrimidine Chemical Properties, Uses, Production
Chemical Properties
White solid
Synthesis
81560-03-4
63810-78-6
Step 3, Preparation of 5-bromo-4-chloro-2-methylthiopyrimidine: 5-bromo-2-(methylthio)pyrimidin-4(3H)-one (110 g) was dissolved in pyridine (400 g) and heated to 80°C. Phosphorus trichloride (100 g) was added dropwise with stirring. After the dropwise addition, the reaction temperature was maintained and stirring was continued for 5 hours. After completion of the reaction, the reaction mixture was cooled to room temperature and subsequently placed in an ice bath. The pH was adjusted to 8-9 with saturated sodium bicarbonate solution and then extracted with ethyl acetate (500 mL). The organic phase was dried with anhydrous magnesium sulfate, filtered and the filtrate was concentrated under reduced pressure to remove the solvent. The residue was recrystallized by a solvent mixture of petroleum ether and ethyl acetate (1:3, v/v) to give a pale yellow solid powder (98 g) in 83% yield.
References
[1] Patent: CN107488175, 2017, A. Location in patent: Paragraph 0008; 0010
[2] Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1982, vol. 36, # 1 B, p. 15 - 18
5-Bromo-4-chloro-2-methylsulfanyl-pyrimidine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Qinuo Chemical Co., Ltd.Co., Ltd. | 0519-0519-83812535 | sales@qinuochem.com | China | 287 | 60 |
| Nanjing Habo Medical Technology Co., Ltd. | 13376080562 13376090521 | sales@habotech.com | China | 724 | 60 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
View Latest Price from 5-Bromo-4-chloro-2-methylsulfanyl-pyrimidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE
63810-78-6
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2025-05-23 | 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE
63810-78-6
|
$150.00 | 1kg | 99% | 500kg | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2021-07-13 | 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE
63810-78-6
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE
63810-78-6
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE
63810-78-6
- $150.00
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE
63810-78-6
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
