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2-Thiouracil

2-Thiouracil Structure
2-Thiouracil structure
CAS No.
141-90-2
Chemical Name:
2-Thiouracil
Synonyms
TU;2-thioxo-2,3-dihydropyriMidin-4(1H)-one;Thiouracil;2-TU;DERACIL;Nobilen;THIURACIL;NSC 19473;Thiouraci;tiouracyl
CBNumber:
CB5769908
Molecular Formula:
C4H4N2OS
Molecular Weight:
128.15
MDL Number:
MFCD00006039
MOL File:
141-90-2.mol
Modify Date:2023-05-18
Request For Quotation

2-Thiouracil Properties

Melting point >300 °C (lit.)
Density 1.368 (estimate)
refractive index 1.7000 (estimate)
storage temp. Store below +30°C.
solubility 7.9g/l
form Fine Crystalline Powder
pka pKa 7.46 (Uncertain)
color White to cream
Water Solubility 0.5 g/L
λmax 271nm(H2O)(lit.)
Merck 14,9366
BRN 112227
InChIKey ZEMGGZBWXRYJHK-UHFFFAOYSA-N
CAS DataBase Reference 141-90-2(CAS DataBase Reference)
EWG's Food Scores 2
FDA UNII 59X161SCYL
Proposition 65 List Thiouracil
NIST Chemistry Reference 2-Thiouracil(141-90-2)
IARC 2B (Vol. Sup 7, 79) 2001
EPA Substance Registry System Thiouracil (141-90-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Warning
Hazard statements  H351
Precautionary statements  P281
Hazard Codes  Xn,T
Risk Statements  40-45-20/21/22
Safety Statements  36/37-53-45
WGK Germany  3
RTECS  YR1575000
TSCA  Yes
HS Code  29335995
NFPA 704
0
1 0

2-Thiouracil price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T7750 2-Thiouracil ≥99% 141-90-2 25g $57.9 2023-01-07 Buy
Sigma-Aldrich T7750 2-Thiouracil ≥99% 141-90-2 1kg $760 2023-01-07 Buy
TCI Chemical T0224 2-Thiouracil >98.0%(HPLC)(T) 141-90-2 25g $43 2023-01-07 Buy
TCI Chemical T0224 2-Thiouracil >98.0%(HPLC)(T) 141-90-2 250g $248 2023-01-07 Buy
Sigma-Aldrich T7750 2-Thiouracil ≥99% 141-90-2 100g $159 2023-01-07 Buy
Product number Packaging Price Buy
T7750 25g $57.9 Buy
T7750 1kg $760 Buy
T0224 25g $43 Buy
T0224 250g $248 Buy
T7750 100g $159 Buy

2-Thiouracil Chemical Properties,Uses,Production

Chemical Properties

white to cream fine crystalline powder

Uses

2-Thiouracil has been used in the synthesis and characterization of silver colloid and film substrates and their applications in surface-enhanced Raman scattering (SERS)

Uses

antiviral, thyroid depressant

Uses

Reagent used in the preparation of Antithyroid agents.

Definition

ChEBI: A nucleobase analogue that is uracil in which the oxo group at C-2 is replaced by a thioxo group.

Biochem/physiol Actions

2-Thiouracil is a thio-derivative of uracil, a pyrimidine nucleobase. It acts as an anticancer, antithyroid, and antiviral agent. 2-Thiouracil is a selective melanoma-seeker and competitive inhibitor of neuronal nitric oxide synthase. It also forms complexes with transition metals such as gold (Au), Chromium (Cr), Zinc (Zn), and Silver (Ag).

Safety Profile

Moderately toxic by ingestion. Human teratogenic effects by unspecified routes: developmental abnormalities of the central nervous system, craniofacial area, and endocrine system. Human reproductive effects by unspecified route: effects on newborn, including viabllity index changes. Experimental teratogenic effects. Other experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx. Used in the treatment of hyperthyroidism, angina pectoris, and congestive heart failure. See also MERCAPTANS and KETONES.

Purification Methods

Crystallise 2-thiouracil from water or EtOH. [Beilstein 24 H 323, 24 I 315, 24 II 171, 24 III/IV 1237.]

2-Thiouracil Preparation Products And Raw materials

Raw materials

Sodium methoxide Thiourea 4-AMINO-2-MERCAPTOPYRIMIDINE 2-THIOURIDINE

Preparation Products

PYRIMIDIN-4-OL 4-CHLORO-N-METHYLPYRIMIDIN-2-AMINE N-(4-AMINOPYRIMIDIN-2-YL)-N-METHYLAMINE 5-BROMO-4-CHLORO-2-METHYLSULFANYL-PYRIMIDINE Pyrimidine, 4-bromo- (8CI,9CI)
4-THIOURACIL 4-Hydroxypyrimidine 4-Pyrimidinol BENZYL-(2-METHYLSULFANYL-PYRIMIDIN-4-YL)-AMINE 4-Chloro-2-(methylsulfonyl)pyrimidine
5-BROMO-4-CHLORO-2-METHANESULFONYL-PYRIMIDINE 2-Methylthio-4-pyrimidinol 4-Chloro-2-methylthiopyrimidine DITHIOURACIL 5-(morpholinomethyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone
4-HYDROXY-2-PHENYLPYRIMIDINE

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2-Thiouracil Suppliers

Global( 517)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou Measure Life Technology Co., LTD 		+8613343730176 2924244016@qq.com China 80 58
Tangshan Moneide Trading Co., Ltd.
+86-315-8309571 +8615633399667 sales@moneidechem.com China 543 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29810 60
Henan DaKen Chemical CO.,LTD. 		+86-371-66670886 info@dakenchem.com China 18267 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21975 55
Hangzhou FandaChem Co.,Ltd. 		+8615858145714 fandachem@gmail.com China 9407 55
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29922 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD 		+86 18953170293 sales@sdzschem.com CHINA 2933 58
Shenzhen Nexconn Pharmatechs Ltd 		15013857715 admin@nexconn.com CHINA 3004 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 5607 58
Supplier Advantage
Hangzhou Measure Life Technology Co., LTD 		58
Tangshan Moneide Trading Co., Ltd.
58
Capot Chemical Co.,Ltd. 		60
Henan DaKen Chemical CO.,LTD. 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
career henan chemical co 		58
SHANDONG ZHI SHANG CHEMICAL CO.LTD 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Jinan Carbotang Biotech Co.,Ltd. 		58

Related articles

  • What is 2-Thiouracil?
  • 2-Thiouracil is a sulfur-containing uracil. An established antithyroid drug and highly selective inhibitor of nitric oxide syn....
  • Jan 6，2020

View Lastest Price from 2-Thiouracil manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Thiouracil pictures 2023-05-26 2-Thiouracil
141-90-2
 US $268.00-250.00 / kilograms 1kilograms 99% 100tons Hebei Dangtong Import and export Co LTD
2-Thiouracil pictures 2023-05-10 2-Thiouracil
141-90-2
 US $0.00 / KG 100g 98%+ 100kg WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
2-Thiouracil pictures 2023-04-21 2-Thiouracil
141-90-2
 US $0.00 / KG 1KG 99.5% 10000 Wuhan Silworld Chemical Co.,Ltd
  • 2-Thiouracil pictures
  • 2-Thiouracil
    141-90-2
  • US $268.00-250.00 / kilograms
  • 99%
  • Hebei Dangtong Import and export Co LTD
  • 2-Thiouracil pictures
  • 2-Thiouracil
    141-90-2
  • US $0.00 / KG
  • 98%+
  • WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
  • 2-Thiouracil pictures
  • 2-Thiouracil
    141-90-2
  • US $0.00 / KG
  • 99.5%
  • Wuhan Silworld Chemical Co.,Ltd

2-Thiouracil Spectrum

2-Thiouracil(141-90-2)MS2-Thiouracil(141-90-2)1HNMR2-Thiouracil(141-90-2)13CNMR2-Thiouracil(141-90-2)IR12-Thiouracil(141-90-2)IR22-Thiouracil(141-90-2)Raman

141-90-2(2-Thiouracil)Related Search:

Tizoxanide-d4 Tiotropium D3 iodide CHLOROPHOSPHONAZO III 6-BENZYL-2-THIOURACIL 7-AMINO-4-OXO-5-PHENYL-2-THIOXO-1,3,5,8-TETRAHYDRO-8-OXAQUINAZOLINE-6-CARBONITRILE
6-AMINO-2-THIOURACIL,4-Amino-2-thiouracil BUTTPARK 116\40-76 2-THIOOROTIC ACID 5-ETHYL-2-THIOURACIL 5,6-DIMETHYL-2-THIOURACIL
BUTTPARK 116\40-69 3-AMINO-6-METHYL-2-THIOXO-2,3-DIHYDRO-4(1H)-PYRIMIDINONE BUTTPARK 116\40-78 BUTTPARK 116\40-77 5,6-DIAMINO-2-THIOURACIL,4,5-DIAMINO-2-THIOURACIL
6-AMINO-4-OXO-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YLFORMAMIDE 5-METHYL-2-THIOURACIL 6-FORMYL-2-THIOURACIL,6-FORMYL-2-THIOURACIL H2O

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DERACIL 2,3-dihydro-2-thioxo-4(1h)-pyrimidinon Thiourea pyriMidine 2-Thiouracil, TU 2-mercapto-4(1h)-pyrimidinone 2-mercapto-4-pyrimidino 2-Mercapto-4-pyrimidinol 2-Mercaptopyrimid-4-one 2-Sulfanyl-4-pyrimidinol 2-Thio-1,3-pyrimidin-4-one 2-thio-2,4-(1h,3h)-pyrimidinedione 2-thio-4-oxo-1,3-pyrimidine 2-thio-4-oxypyrimidine 2-thio-6-oxypyrimidine Uracil, 2-thio- 4-HYDROXY-2-MERCAPTOPYRIMIDINE / 2-THIOURACIL 2-THIO-URACYLE THIURACIL 2-THIOURACIL VETRANAL, 250 MG 2-ThiouracilForSynthesis 2-Thiouracil, 98+% 4(1H)-Pyrimidinone, 2,3-dihydro-2-thioxo- (9CI) 2-HYDROXY-2-MERCAPTOPYRIMIDINE 2-THIOURACIL extrapure 2-Sulfanylidene-1H-pyrimidin-4-one 2-Thiouracil ,99% 2-Thioxo-2,3-dihydro-1H-pyrimidin-4-one 2-sulfanylidene-1,2,3,4-tetrahydropyriMidin-4-one 2-Mercapto-4-pyriMidinone NSC 19473 2-THIOURACIL, [4-HYDROXY-2-MERCAPTOPYRIMIDINE] 2-Thiouracil Vetec(TM) reagent grade, 99% 2-ThiouraCll 4-HYDROXY-2-MERCAPTOPYRIMIDINE 4-HYDROXY-2-THIOPYRIMIDINE 2-MERCAPTO-4-PYRIMIDONE 2-MERCAPTO-4-HYDROXYPYRIMIDINE 2-thio-uraci 2-TU 4(1H)-Pyrimidinone, 2,3-dihydro-2-thioxo- 4(1H)-Pyrimidinone,2,3-dihydro-2-thioxo- 4-hydroxy-2(1h)-pyrimidinethione 4-Hydroxy-2-pyrimidinethiol 4-Pyrimidinol, 2-mercapto- 6-Hydroxy-2-mercaptopyrimidine 6-Thiouracil Antagothyroid Antagothyroil nci-c01490 Nobilen Thiouraci tiouracyl NSC 290412 NSC 290413 NSC 290414 2-Mercapto-4-hydroxypyrimidine 2-Mercapto-4-pyrimidone 2-THIOURACIL 2,3-dihydro-2-thioxo-4(1h)-pyrimidinone