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LY 171883

LY 171883
LY 171883 structure
CAS No.
88107-10-2
Chemical Name:
LY 171883
Synonyms
S-1414;LY 171883;LY-171,833;TOMELUKAST;5-[4-4-ACETYL-3-HYDROXY-2-PROPYLPHENOXYBUTYL]-1H-TETRAZOLE;5-[4-(1-ACETYL-2-HYDROXY-3-PROPYLPHENOXY)BUTYL]-1H-TETRAZOLE;2’-hydroxy-3’-propyl-4-(4-(1h-tetrazol-5-yl)butoxy)-acetophenon;1-(2-hydroxy-3-propyl-4-(4-(1h-tetrazol-5-yl)butoxy)phenyl)-ethanon;1-[2-HYDROXY-3-PROPYL-4-[4-(1H-TETRAZOL-5-YL)BUTOXY]PHENYL]ETHANONE;1-[2-hydroxy-3-propyl-4-[4-(2H-tetrazol-5-yl)butoxy]phenyl]ethanone
CBNumber:
CB1666122
Molecular Formula:
C16H22N4O3
Formula Weight:
318.37
MOL File:
88107-10-2.mol

LY 171883 Properties

Melting point:
117-119℃
storage temp. 
Store at +4°C
form 
White solid.
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36
WGK Germany  3
RTECS  KM5780800
Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P330 Rinse mouth.

LY 171883 price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar J67028 LY 171883, 98% 88107-10-2 10mg $124 2018-11-13 Buy
Cayman Chemical 70710 LY171883 ≥98% 88107-10-2 5mg $32 2018-11-13 Buy
Cayman Chemical 70710 LY171883 ≥98% 88107-10-2 10mg $61 2018-11-13 Buy
Cayman Chemical 70710 LY171883 ≥98% 88107-10-2 50mg $256 2018-11-13 Buy
Cayman Chemical 70710 LY171883 ≥98% 88107-10-2 100mg $448 2018-11-13 Buy

LY 171883 Chemical Properties,Uses,Production

Uses

Selective, orally active leukotriene D4 antagonist. Has been shown to bind to the γ-isoform of the peroxisome proliferator-activated receptor (PPARγ).

Definition

ChEBI: A member of the class of acetophenones that is 1-phenylethanone substituted at position 2 by a hydroxy group, a propyl group at position 3 and a 4-(1H-tetrazol-5-yl)butoxy group at position 4. A leukotriene antagonist, it exhibits anti asthmatic activity.

Biological Activity

Selective, orally active leukotriene D 4 (LTD 4 ) antagonist; inhibits binding of [ 3 H]-LTD 4 to guinea pig lung membranes (K i = 0.63 μ M).? Acts as an agonist at peroxisome proliferator-activated receptors (PPARs).

LY 171883 Preparation Products And Raw materials

Raw materials

Preparation Products


LY 171883 Suppliers

Global( 33)Suppliers
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Hubei xin bonus chemical co. LTD
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