ChemicalBook
Chinese Japanese Germany

2-Bromothiazole

Description Referrence
2-Bromothiazole
2-Bromothiazole
CAS No.
3034-53-5
Chemical Name:
2-Bromothiazole
Synonyms
TZ-Br;CL028;NSC 91532;2-Bromthiazol;2-BROMOTHIAZOLE;2-bromo-thiazol;2-BROMOTHIOAZOLE;Thiazole, 2-bromo-;2-THIAZOLYL BROMIDE;TIMTEC-BB SBB003918
CBNumber:
CB1739860
Molecular Formula:
C3H2BrNS
Formula Weight:
164.02
MOL File:
3034-53-5.mol

2-Bromothiazole Properties

Melting point:
171 C
Boiling point:
171 °C(lit.)
Density 
1.82 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.593(lit.)
Flash point:
146 °F
storage temp. 
2-8°C
form 
Liquid
color 
Clear colorless to orange-brown
Specific Gravity
1.836
Water Solubility 
insoluble
BRN 
105724
InChIKey
RXNZFHIEDZEUQM-UHFFFAOYSA-N
CAS DataBase Reference
3034-53-5(CAS DataBase Reference)
NIST Chemistry Reference
Thiazole, 2-bromo-(3034-53-5)
EPA Substance Registry System
Thiazole, 2-bromo-(3034-53-5)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi,F
Risk Statements  36/37/38
Safety Statements  23-24/25-36-26
RIDADR  1993
WGK Germany  3
TSCA  Yes
HazardClass  IRRITANT, FLAMMABLE
HS Code  29341000
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H227 Combustible liquid Flammable liquids Category 4 Warning P210, P280, P370+P378, P403+P235,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

2-Bromothiazole price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 160474 2-Bromothiazole 98% 3034-53-5 5g $42.6 2018-11-13 Buy
Sigma-Aldrich 160474 2-Bromothiazole 98% 3034-53-5 25g $132 2018-11-13 Buy
TCI Chemical B1280 2-Bromothiazole >98.0%(GC) 3034-53-5 25g $99 2018-11-22 Buy
TCI Chemical B1280 2-Bromothiazole >98.0%(GC) 3034-53-5 250g $594 2018-11-22 Buy
Alfa Aesar A14838 2-Bromothiazole, 99% 3034-53-5 25g $128 2018-11-13 Buy

2-Bromothiazole Chemical Properties,Uses,Production

Description

It is usually used as the intermediate or raw material to produce various products in the organic synthesis and pharmaceutical industry, such as 2-acetylthiazole, antibiotics, and anticholinergic drugs. Specifically, this chemical can act as the raw material to produce camalexin through reaction with indolylmagnesium iodide.1 Moreover, this substance has been selected as the reactant to prepare the thiazole Grignard reagents and thiazolyllithium compounds, which can be converted into thiazole-2-carboxylic acid via a halogen-metal exchange reaction.2, 3 In addition, 2-bromothiazole has been used to synthesize N-aryl aminothiazoles, which are found to function as the inhibitors of cyclin-dependent kinases.4 Besides, this compound may be involved in the synthesis of ethynylthiazoles that exhibits a desirable anti-inflammatory activity.5

Referrence

  1. Ayer, W. A.; Craw, P. A.; Ma, Y. T.; Miao, S. C., SYNTHESIS OF CAMALEXIN AND RELATED PHYTOALEXINS. Tetrahedron 1992, 48, 2919-2924.
  2. Kurkjy, R. P.; Brown, E. V., THE PREPARATION OF THIAZOLE GRIGNARD REAGENTS AND THIAZOLYLLITHIUM COMPOUNDS. J. Am. Chem. Soc. 1952, 74, 6260-6262.
  3. Beyerman, H. C.; Berben, P. H.; Bontekoe, J. S., THE SYNTHESIS OF THIAZOLE-2-CARBOXYLIC AND OF THIAZOLE-5-CARBOXYLIC ACID VIA A HALOGEN-METAL EXCHANGE REACTION. Recl. Trav. Chim. Pays-Bas-J. Roy. Neth. Chem. Soc. 1954, 73, 325-332.
  4. Misra, R. N.; Xiao, H. Y.; Williams, D. K.; Kim, K. S.; Lu, S. F.; Keller, K. A.; Mulheron, J. G.; Batorsky, R.; Tokarski, J. S.; Sack, J. S.; Kimball, D.; Lee, F. Y.; Webster, K. R., Synthesis and biological activity of N-aryl-2-aminothiazoles: potent pan inhibitors of cyclin-dependent kinases. Bioorg. Med. Chem. Lett. 2004, 14, 2973-2977.
  5. Geronikaki, A.; Vasilevsky, S.; Hadjipavlou-Litina, D.; Lagunin, A.; Poroikov, B. V., Synthesis and anti-inflammatory activity of ethynylthiazoles. Khim. Geterotsiklicheskikh Soedin. 2006, 769-774.

Chemical Properties

Colourless Liquid

Uses

Aryl halide used to N-arylate 5- and 7-azaindoles.1 Copper-catalyzed cyanation provides 2-cyanothiazole.2

Uses

2-Bromothiazole is a heterocyclic S compound to induce base-pair substitution and having mutagenic activity.

2-Bromothiazole Preparation Products And Raw materials

Raw materials

Preparation Products


2-Bromothiazole Suppliers

Global( 289)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19953 60
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Accela ChemBio Inc.
(+1)-858-699-3322
(+1)-858-876-1948 info@accelachem.com CHINA 12156 58
Hubei Jusheng Technology Co.,Ltd.
86-155-27864001
peter@hubeijusheng.com CHINA 18004 58
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 955 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 19990 58
ChangZhou Chemfarmer Foreign Trade Co.,Ltd +86-(0)519-89886667 18516062846
+86-(0)519-89886667 sales@chemfarmer.com China 339 58
Creasyn Finechem(Tianjin) Co., Ltd. 86-22-83945878,83945171,83945172
4008266163-06019 export@creasyn.com sale@creasyn.com China 853 68
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) sh@meryer.com China 40395 62

View Lastest Price from 2-Bromothiazole manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-20 2-Bromothiazole
3034-53-5
US $1.00 / kg 1kg 98%min 1000kg career henan chemical co

2-Bromothiazole Spectrum


3034-53-5(2-Bromothiazole)Related Search:


Copyright 2017 © ChemicalBook. All rights reserved