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Benzothiazole

Benzothiazole
Benzothiazole structure
CAS No.
95-16-9
Chemical Name:
Benzothiazole
Synonyms
o-2857;NSC 8040;vangardbt;FEMA 3256;Vangard BT;usafek-4812;USAF ek-4812;Benzthiazole;Benzothiazol;BENZOTHIAZOLE
CBNumber:
CB1720657
Molecular Formula:
C7H5NS
Formula Weight:
135.19
MOL File:
95-16-9.mol

Benzothiazole Properties

Melting point:
2 °C(lit.)
Boiling point:
231 °C(lit.)
Density 
1.238 g/mL at 25 °C(lit.)
vapor density 
4.66 (vs air)
vapor pressure 
34 mm Hg ( 131 °C)
refractive index 
n20/D 1.642(lit.)
FEMA 
3256 | BENZOTHIAZOLE
Flash point:
>230 °F
storage temp. 
Refrigerator
solubility 
3g/l
form 
Liquid
color 
Clear yellow-brown to brown
explosive limit
0.9-8.2%(V)
Water Solubility 
slightly soluble
JECFA Number
1040
Merck 
14,1107
BRN 
109468
Stability:
Stable - regarded as highly persistent in the environment. Incompatible with strong oxidizing agents. Combustion products: nitrogen oxides, carbon monoxide, carbon dioxide, sulphur oxides.
InChIKey
IOJUPLGTWVMSFF-UHFFFAOYSA-N
CAS DataBase Reference
95-16-9(CAS DataBase Reference)
NIST Chemistry Reference
Benzothiazole(95-16-9)
EPA Substance Registry System
Benzothiazole(95-16-9)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H302-H311-H320-H402-H301-H301+H311-H319-H332
Precautionary statements  P280-P301+P310-P305+P351+P338-P312-P301+P310+P330-P302+P352+P312-P261-P301+P310a-P501a-P264-P270-P273-P301+P312+P330-P302+P352+P312+P361+P364-P305+P351+P338+P337+P313-P405-P501
Hazard Codes  Xn,T,Xi
Risk Statements  22-20/21/22-36-25-24-20
Safety Statements  23-26-36-36/37-45
RIDADR  2810
WGK Germany  2
RTECS  DL0875000
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29342080
Toxicity LD50 i.v. in mice: 95±3 mg/kg (Domino)

Benzothiazole price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 101338 Benzothiazole 96% 95-16-9 5g $24.6 2018-11-13 Buy
Sigma-Aldrich 101338 Benzothiazole 96% 95-16-9 100g $34 2018-11-13 Buy
TCI Chemical B0092 Benzothiazole >96.0%(GC) 95-16-9 25mL $15 2018-11-22 Buy
TCI Chemical B0092 Benzothiazole >96.0%(GC) 95-16-9 100mL $35 2018-11-22 Buy
Alfa Aesar A10380 Benzothiazole, 97% 95-16-9 250g $53.2 2018-11-13 Buy

Benzothiazole Chemical Properties,Uses,Production

Description

Benzothiazole and its derivative are recognized as the most important heterocyclic compounds. This series of compounds is of particular interests. It has various kinds of pharmacological properties and has been included in many kinds of natural products and pharmaceutical agents. The broad spectrum of pharmacological activity in individual benzothiazole derivative enables it to serve as unique and valuable scaffolds for experimental drug design. It is already known that benzothiazole and its derivative has various biological applications including anticancer, antimicrobial, anticonvulsant, antiviral, antidiabetic, antipsychotic, antiinflammatory, analgesic, fungicidal and diuretic. Its derivatives also have many applications in polymer chemistry, dyes, drugs, and silver photography as well as rubber industry.

Chemical Properties

yellow liquid with an unpleasant odour

Chemical Properties

Benzothiazole has a delicate, persistent, rose-like odor similar to that of quinoline.

Occurrence

Reported found in apricot, cooked asparagus, mozzarella cheese, skim milk powder, roasted beef, beer, malt whiskey, coconut meat, fresh mango, cooked broccoli and kelp.

Uses

In organic synthesis.

Uses

Various benzothiazole-benzamides synthesized were evaluated for their analgesic and antidepressant activities.

Definition

ChEBI: An organic heterobicyclic compound that is a fusion product between benzene and thiazole. The parent of the class of benzothiazoles.

Preparation

By refluxing a mixture of zinc o-aminophenylsulfide and formic acid, followed by steam distillation of the alkalized reaction mixture; by heating formanilid or dimethylaniline with sulfur; by oxidation of 2-mercaptobenzothiazole or of the corresponding disulfide.

Aroma threshold values

Detection: 80 to 450 ppb

Taste threshold values

Taste characteristics at 3 ppm: meaty, vegetative, brown, cooked, beefy and coffee-like.

Hazard

Highly toxic by ingestion.

References

Gupta, Akhilesh, and S. Rawat. "Synthesis and cyclization of benzothiazole." J. of Current Pharmaceutical Research 3.1 (2010): 13-25.
Keri, Rangappa S., et al. "A comprehensive review in current developments of benzothiazole-based molecules in medicinal chemistry." European journal of medicinal chemistry 89 (2015): 207-251.
Khokra, Sukhbir L., et al. "Common methods to synthesize benzothiazole derivatives and their medicinal significance: a review." International Journal of Pharmaceutical Sciences and Research 2.6 (2011): 1356.

Benzothiazole Preparation Products And Raw materials

Raw materials

Preparation Products


Benzothiazole Suppliers

Global( 228)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21696 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30001 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23980 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58
Jinan Finer Chemical Co., Ltd
+86-531-88989536
+86-531-88989539 sales@finerchem.com CHINA 947 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8921 58
Shandong chuangyingchemical Co., Ltd.
13156170209
sale@chuangyingchem.com CHINA 4405 58
BOC Sciences
1-631-619-7922
1-631-614-7828 inquiry@bocsci.com United States 20115 58

View Lastest Price from Benzothiazole manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-07-28 Benzothiazole
95-16-9
US $100.00 / KG 25KG 98% 1000KG career henan chemical co

Benzothiazole Spectrum


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