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aprikalim

CAS No.
89544-10-5
Chemical Name:
aprikalim
Synonyms
RP-49356;aprikalim;N-Methyl-2-(3-pyridyl)tetrahydrothiopyran-2-carbothioamide-1-oxide;N-Methyl[tetrahydro-2-(3-pyridyl)-2H-thiopyran]-2-carbothioamide 1-oxide;N-Methyl-[tetrahydro-2-(3-pyridinyl)-2H-thiopyran]-2-carbothioamide 1-oxide;2H-Thiopyran-2-carbothioamide, tetrahydro-N-methyl-2-(3-pyridinyl)-, 1-oxide;2-(Methylaminocarbonothioyl)-2-(3-pyridinyl)-tetrahydro-2H-thiopyran 1-oxide
CBNumber:
CB21319572
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
89544-10-5.mol
Last updated:2025-04-18 09:51:49
Product description Number Pack Size Price
APRIKALIM 95.00% API0005965 5MG $497.7

aprikalim Properties

FDA UNII 374BH4KVRG

aprikalim price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0005965 APRIKALIM 95.00% 89544-10-5 5MG $497.7 2021-12-16 Buy
Product number Packaging Price Buy
API0005965 5MG $497.7 Buy

aprikalim Chemical Properties,Uses,Production

Uses

rel-Aprikalim (rel-RP 52891) is the relative configuration of Aprikalim (HY-121183). Aprikalim (RP 52891), a potassium channel opener (KCO), activates ATP-sensitive K+ (KATP) channels in guinea pig ventricular myocytes[1].

References

[1] D Thuringer, et al. Time-dependent fading of the activation of KATP channels, induced by aprikalim and nucleotides, in excised membrane patches from cardiac myocytes. Br J Pharmacol. 1995 May;115(1):117-27. DOI:10.1111/j.1476-5381.1995.tb16328.x

aprikalim Preparation Products And Raw materials

Raw materials

Preparation Products

aprikalim 2-(Methylaminocarbonothioyl)-2-(3-pyridinyl)-tetrahydro-2H-thiopyran 1-oxide N-Methyl-[tetrahydro-2-(3-pyridinyl)-2H-thiopyran]-2-carbothioamide 1-oxide N-Methyl[tetrahydro-2-(3-pyridyl)-2H-thiopyran]-2-carbothioamide 1-oxide RP-49356 2H-Thiopyran-2-carbothioamide, tetrahydro-N-methyl-2-(3-pyridinyl)-, 1-oxide N-Methyl-2-(3-pyridyl)tetrahydrothiopyran-2-carbothioamide-1-oxide 89544-10-5