ChemicalBook >> CAS DataBase List >>TAS 103
TAS 103
- CAS No.
- 174634-08-3
- Chemical Name:
- TAS 103
- Synonyms
- TAS 103;CS-1287;BMS-247615;TAS-103 HC1;TAS-103 base;TAS-103(salt);TA103(bms-247615);6-[[2-(Dimethylamino)ethyl]amino]-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one;7H-Indeno[2,1-c]quinolin-7-one, 6-[[2-(dimethylamino)ethyl]amino]-3-hydroxy-
- CBNumber:
- CB21321579
- Molecular Formula:
- C20H19N3O2
- Molecular Weight:
- 333.38
- MDL Number:
- MFCD26960891
- MOL File:
- 174634-08-3.mol
- MSDS File:
- SDS
Last updated:2023-05-21 10:59:17
| Melting point | 216-217 °C(Solv: ethanol (64-17-5)) |
|---|---|
| Boiling point | 589.5±50.0 °C(Predicted) |
| Density | 1.350±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| pka | 7.88±0.20(Predicted) |
| FDA UNII | YVC96489QV |
TAS 103 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Crysdot | CD31002974 | TAS-103 98+% | 174634-08-3 | 5mg | $83 | 2021-12-16 | Buy |
| Crysdot | CD31002974 | TAS-103 98+% | 174634-08-3 | 10mg | $132 | 2021-12-16 | Buy |
| Crysdot | CD31002974 | TAS-103 98+% | 174634-08-3 | 50mg | $381 | 2021-12-16 | Buy |
| Crysdot | CD31002974 | TAS-103 98+% | 174634-08-3 | 100mg | $658 | 2021-12-16 | Buy |
| DC Chemicals | DC7898 | TAS-103(BMS247615) >98% | 174634-08-3 | 250mg | $1100 | 2021-12-16 | Buy |
TAS 103 Chemical Properties,Uses,Production
Biological Activity
TAS-103 is a dual DNA topoisomerase I/II (topoisomerase I/II) inhibitor for cancer research.
in vivo
TAS-103 (30 mg/kg, iv) causes significant tumor growth suppression in mice bearing Lewis lung carcinoma (LLC) cells, without obvious body weight loss, and the liposomal TAS-103 is more active than free TAS-103.
target
| Topoisomerase I
| Topoisomerase II
|
TAS 103 Preparation Products And Raw materials
Raw materials
Preparation Products
TAS 103 Suppliers
Global( 30)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 | |
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2384 | 58 |
| SPIRO PHARMA | eric_feng1954@126.com | China | 9254 | 55 | |
| ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 | 2853530910@QQ.com | China | 8011 | 62 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2983 | 58 |
| Medi-tech Bioscientific Co., Ltd. | 0519-83246372 13585352506 | China | 1844 | 58 | |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4662 | 60 |
| Shanghai BetterBioChem Co., Ltd. | +86-18017644823 | sales@betterbiochem.com | China | 325 | 58 |
TAS 103
6-[[2-(Dimethylamino)ethyl]amino]-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one
TAS-103 HC1
TA103(bms-247615)
BMS-247615
TAS-103(salt)
TAS-103 base
CS-1287
7H-Indeno[2,1-c]quinolin-7-one, 6-[[2-(dimethylamino)ethyl]amino]-3-hydroxy-
174634-08-3