D-Glucosamine hydrochloride
- CAS No.
- 66-84-2
- Chemical Name:
- D-Glucosamine hydrochloride
- Synonyms
- GLUCOSAMINE HYDROCHLORIDE;GLUCOSAMINE HCL;D-GLUCOSAMINE HCL;D-Glucosamine Salt;Glucosamine for system suitability CRS;2-amino-2-deoxy-D-glucose hydrochloride (1:1);cosamin;NSC 758;D-GLCN HCL;NSC 234443
- CBNumber:
- CB2181059
- Molecular Formula:
- C6H14ClNO5
- Molecular Weight:
- 215.63
- MDL Number:
- MFCD00135831
- MOL File:
- 66-84-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Glucosamine hydrochloride European Pharmacopoeia (EP) Reference Standard | Y0001406 | 15 mg | $225 |
| Glucosamine for system suitability European Pharmacopoeia (EP) Reference Standard | Y0001381 | 3 mg | $236 |
| D-(+)-Glucosamine hydrochloride ≥99%, BioReagent, suitable for cell culture | G1514 | 100g | $79.3 |
| Glucosamine hydrochloride United States Pharmacopeia (USP) Reference Standard | 1294207 | 200mg | $422 |
| D-(+)-Glucosamine Hydrochloride >98.0%(T) | G0044 | 25g | $28 |
| More product size | |||
| Melting point | 190-194 °C (dec.)(lit.) |
|---|---|
| alpha | 72.5 º (c=2, H2O, 5hrs.) |
| refractive index | 72 ° (C=1, H2O) |
| storage temp. | 2-8°C |
| solubility | H2O: 0.1 g/mL, clear, colorless |
| form | crystalline |
| color | White |
| biological source |
Aspergillus niger maize fruit |
| Water Solubility | soluble |
| Merck | 14,4458 |
| BRN | 4157370 |
| Stability | Stable. Incompatible with strong oxidizing agents. Combustible. |
| Cosmetics Ingredients Functions |
ANTISTATIC HAIR CONDITIONING |
| InChI | InChI=1/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/s3 |
| InChIKey | QKPLRMLTKYXDST-LPRXMDNASA-N |
| SMILES | [C@H]1(CO)OC([C@H](N)[C@@H](O)[C@@H]1O)O.Cl |&1:0,5,7,9,r| |
| LogP | -2.375 (est) |
| CAS DataBase Reference | 66-84-2(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 750W5330FY |
| EPA Substance Registry System | D-Glucose, 2-amino-2-deoxy-, hydrochloride (66-84-2) |
| UNSPSC Code | 41116107 |
| NACRES | NA.79 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P271-P280 | |||||||||
| Hazard Codes | F,Xi,Xn | |||||||||
| Risk Statements | 21-36/38-46-62-63 | |||||||||
| Safety Statements | 24/25-53-36/37-26-25 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | LZ6665000 | |||||||||
| F | 3-10 | |||||||||
| Hazard Note | Highly Flammable | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29329985 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
D-Glucosamine hydrochloride price More Price(68)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0001406 | Glucosamine hydrochloride European Pharmacopoeia (EP) Reference Standard | 66-84-2 | 15 mg | $225 | 2025-07-31 | Buy |
| Sigma-Aldrich | Y0001381 | Glucosamine for system suitability European Pharmacopoeia (EP) Reference Standard | 66-84-2 | 3 mg | $236 | 2025-07-31 | Buy |
| Sigma-Aldrich | G1514 | D-(+)-Glucosamine hydrochloride ≥99%, BioReagent, suitable for cell culture | 66-84-2 | 100g | $79.3 | 2025-07-31 | Buy |
| Sigma-Aldrich | 1294207 | Glucosamine hydrochloride United States Pharmacopeia (USP) Reference Standard | 66-84-2 | 200mg | $422 | 2025-07-31 | Buy |
| TCI Chemical | G0044 | D-(+)-Glucosamine Hydrochloride >98.0%(T) | 66-84-2 | 25g | $28 | 2025-07-31 | Buy |
D-Glucosamine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
white powder
Uses
Novel application of D-Glucosamine hydrochloride to prepare medical agent for treating vertigo. Found in chitin, in mucoproteins, and in mucopolysaccharides. Antiarthritic. Recent studies show that its chondroprotective activity is related to its antiapoptic properties.
Uses
Novel application of glucosamine is to prepare medical agent for treating vertigo. It is used as food ingredients and additives, raw material for anti cancer and antibiotic drugs.
Uses
glucosamine hydrochloride (glucosamine HCl) is used to adjust the pH of a formulation. It also has anti-static and hair-conditioning properties.
General Description
D-Glucosamine hydrochloride is frequently employed as a dietary supplement to support joint health and alleviate inflammation. It is recognized for its role in the biosynthesis of glycosaminoglycans and subsequently in the formation of cartilage and joint tissues.
Biochem/physiol Actions
Glucosamine is preferred as a nutritional supplement?for individuals with osteoarthritis. It is used as a building block for the production of proteoglycans?and?glycosaminoglycans.
Purification Methods
Crystallise the hydrochloride from 3M HCl, water, and finally water/EtOH/acetone as for galactosamine hydrochloride. [Purchase & Braun Org Synth 26 36 1946, Stacey & Webber Methods in Carbohydrate Chemistry I 228 1962, Academic Press.] The salt has also been purified by dissolving in the minimum volume of boiling H2O (charcoal), filtering and adding a large excess of 95% EtOH (~4 volumes) and stirring vigorously for several hours. Collect the crystals after 4-6hours to give anomer which mutarotates ] D +100o to +72o (equilibrium, c 1, H2O). A large amount of the -anomer stays in solution. This can be precipitated from the filtrate by adding excess Et2O. The mixture of -plus -anomers has [] D +68.8o (c 4.75, H2O, mutarotating to +70.1o)[Leaback Biochemical Preparations 10 118 1963]. Note that if Et2NH is used instead of Et3N, conversion to the -anomer can be complete (see above). [Stacey et al. Methods in Carbohydrate Chemistry I 3061962, Academic Press; Beilstein 4 IV 2018.]
D-Glucosamine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Zelixir Biotech Co., Ltd. | +8618867646786 | neal.chen@zelixir.com | China | 232 | 58 |
| Nantong Chem-land Co.,Ltd. | +undefined13862903883 | sales@chem-land.com | China | 61 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8754 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-18192627656 | 1059@dideu.com | China | 3590 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5242 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| zhuzhou dingcheng meihei comestic co.,ltd | +8618873369619 | dingchengbusiness8@163.com | China | 260 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20129 | 58 |
| Shandong Juchuang Chemical Co., LTD | +16837774622 | admin@juchuangchem.com | China | 295 | 58 |
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View Lastest Price from D-Glucosamine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-13 | D-Glucosamine hydrochloride
66-84-2
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2026-01-13 | D-Glucosamine hydrochloride
66-84-2
|
US $1.00 / KG | 1KG | ≥98% | 1ton/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2026-01-13 | D-Glucosamine hydrochloride
66-84-2
|
US $5.00-0.50 / KG | 1KG | 99% hplc | 500TONS | Wuhan JiyunZen Tech Co., Ltd. |
-
- D-Glucosamine hydrochloride
66-84-2
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- D-Glucosamine hydrochloride
66-84-2
- US $1.00 / KG
- ≥98%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- D-Glucosamine hydrochloride
66-84-2
- US $5.00-0.50 / KG
- 99% hplc
- Wuhan JiyunZen Tech Co., Ltd.
