CALPAIN INHIBITOR XII
- CAS No.
- 181769-57-3
- Chemical Name:
- CALPAIN INHIBITOR XII
- Synonyms
- CALPAIN INHIBITOR XII;Z-L-NVA-CONH-CH2-2-PY;PLVWMBFPIAQRHK-UHFFFAOYSA-N;(Rac)-Calpain Inhibitor XII;benzyl N-[1-[[1,2-dioxo-1-(pyridin-2-ylmethylamino)hexan-3-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate;Carbamic acid, [3-methyl-1-[[[1-[oxo[(2-pyridinylmethyl)amino]acetyl]butyl]amino]carbonyl]butyl]-, phenylmethyl ester (9CI)
- CBNumber:
- CB2243292
- Molecular Formula:
- C26H34N4O5
- Molecular Weight:
- 482.57
- MDL Number:
- MFCD06411395
- MOL File:
- Mol file
- MSDS File:
- SDS
CALPAIN INHIBITOR XII price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | J64751 | Calpain Inhibitor XII | 181769-57-3 | 1mg | $111 | 2023-06-20 | Buy |
| Alfa Aesar | J64751 | Calpain Inhibitor XII | 181769-57-3 | 5mg | $463 | 2023-06-20 | Buy |
| Cayman Chemical | 14466 | Calpain Inhibitor XII ≥90% | 181769-57-3 | 1mg | $101 | 2024-03-01 | Buy |
| Cayman Chemical | 14466 | Calpain Inhibitor XII ≥90% | 181769-57-3 | 5mg | $449 | 2024-03-01 | Buy |
| Cayman Chemical | 14466 | Calpain Inhibitor XII ≥90% | 181769-57-3 | 10mg | $747 | 2024-03-01 | Buy |
CALPAIN INHIBITOR XII Chemical Properties,Uses,Production
Description
Calpain inhibitor XII is a reversible and selective inhibitor of calpain I (μ-
Uses
A cell-permeable dipeptidyl -ketoamide compound that acts as a potent, selective, reversible, and active site inhibitor of calpain-1
in vitro
a series of new dipeptidyl alpha-keto amides of the general structure r1-l-leu-d,l-aa-conh-r2 including calpain inhibitor xii were synthesized and evaluated as inhibitors for the cysteine proteases calpain i, calpain ii, and cathepsin b. calpain ii was more sensitive to these inhibitors calpain inhibitor xii than calpain i. calpain i was also effectively inhibited by calpain inhibitor xii, but lower ki values than with calpain ii. cathepsin b was weakly inhibited by calpain inhibitor xii. the best calpain i inhibitor in this study was calpain inhibitor xii with ki value of 19 nm [1].
References
[1] li, z. ,ortega-vilain, a.c.,patil, g.s., et al. novel peptidyl α-keto amide inhibitors of calpains and other cysteine proteases. journal of medicinal chemistry 39(20), 4089-4098 (1996).
CALPAIN INHIBITOR XII Preparation Products And Raw materials
Raw materials
Preparation Products
CALPAIN INHIBITOR XII Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| VDM Biochemicals | 0330-2528181 | sales@vdmbio.com | United States | 510 | 64 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | eric@peptidego.com | China | 6347 | 58 |
| Angel Pharmatech, Ltd. | 17317130613 | 3358272972@qq.com | China | 3238 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |
View Lastest Price from CALPAIN INHIBITOR XII manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-01-06 | CALPAIN INHIBITOR XII
181769-57-3
|
US $17.00 / g | 25g | 95% | 1KG | Career Henan Chemica Co |
-
- CALPAIN INHIBITOR XII
181769-57-3
- US $17.00 / g
- 95%
- Career Henan Chemica Co