Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>6-bromo-2-methylimidazo[1,2-a]pyrimidine

6-bromo-2-methylimidazo[1,2-a]pyrimidine

6-bromo-2-methylimidazo[1,2-a]pyrimidine Structure
6-bromo-2-methylimidazo[1,2-a]pyrimidine structure
CAS No.
1111638-05-1
Chemical Name:
6-bromo-2-methylimidazo[1,2-a]pyrimidine
Synonyms
6-bromo-2-methylimidazo[1,2-a]pyrimidine;6-fluoro-2-methylimidazo[1,2-a]pyrimidine;IMidazo[1,2-a]pyriMidine, 6-broMo-2-Methyl-;6-Bromo-2-methylimidazo[1,2-a]pyrimidine 97%
CBNumber:
CB22522458
Molecular Formula:
C7H6BrN3
Molecular Weight:
212.05
MDL Number:
MFCD12024554
MOL File:
1111638-05-1.mol
Last updated:2025-07-24 18:13:43
Product description Number Pack Size Price
6-Bromo-2-methylimidazo[1,2-a]pyrimidine 3H32-9-C8 250mg $239
6-BROMO-2-METHYLIMIDAZO[1,2-A]PYRIMIDINE 95.00% NUC0000899 0.25G $380
6-Bromo-2-methylimidazo[1,2-a]pyrimidine 95% 145041 1g $417
6-bromo-2-methylimidazo[1,2-a]pyrimidine 2000AQ 250mg $420.8
6-Bromo-2-methylimidazo[1,2-a]pyrimidine 97% OR350418 1g $505
Request For Quotation

6-bromo-2-methylimidazo[1,2-a]pyrimidine Properties

Density 1.76±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 4.81±0.30(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933599590

6-bromo-2-methylimidazo[1,2-a]pyrimidine price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
SynQuest Laboratories 3H32-9-C8 6-Bromo-2-methylimidazo[1,2-a]pyrimidine 1111638-05-1 250mg $239 2021-12-16 Buy
American Custom Chemicals Corporation NUC0000899 6-BROMO-2-METHYLIMIDAZO[1,2-A]PYRIMIDINE 95.00% 1111638-05-1 0.25G $380 2021-12-16 Buy
Matrix Scientific 145041 6-Bromo-2-methylimidazo[1,2-a]pyrimidine 95% 1111638-05-1 1g $417 2021-12-16 Buy
AK Scientific 2000AQ 6-bromo-2-methylimidazo[1,2-a]pyrimidine 1111638-05-1 250mg $420.8 2021-12-16 Buy
Apolloscientific OR350418 6-Bromo-2-methylimidazo[1,2-a]pyrimidine 97% 1111638-05-1 1g $505 2021-12-16 Buy
Product number Packaging Price Buy
3H32-9-C8 250mg $239 Buy
NUC0000899 0.25G $380 Buy
145041 1g $417 Buy
2000AQ 250mg $420.8 Buy
OR350418 1g $505 Buy

6-bromo-2-methylimidazo[1,2-a]pyrimidine Chemical Properties,Uses,Production

Synthesis

2-Amino-5-bromopyrimidine

7752-82-1

Chloroacetone

78-95-5

6-bromo-2-methylimidazo[1,2-a]pyrimidine

1111638-05-1

Example B-8: Preparation of (2S)-1-(4-(1-isopropyl-3-(2-methylimidazo[1,2-a]pyrimidin-6-yl)-1H-pyrazol-4-yl)pyrimidin-2-ylamino)propan-2-ol (B-8). Preparation of 6-bromo-2-methylimidazo[1,2-a]pyrimidine (B-8-2). To a mixed solution of 5-bromopyrimidin-2-amine (170.0 g, 0.98 mol) in isopropanol (2 L) and N,N-dimethylformamide (500 mL) was added 1-chloro-2-propanone (606 g, 6.53 mol). The reaction mixture was stirred at 100 °C for 16 hours. Completion of the reaction was confirmed by monitoring the progress of the reaction by thin layer chromatography (TLC) (unfolding agent ratio: petroleum ether/ethyl acetate = 1:2). After completion of the reaction, the reaction was quenched with sodium carbonate (Na2CO3) solution and filtered. The filtrate was concentrated under reduced pressure and the residue was purified by column chromatography (eluent ratio: petroleum ether/ethyl acetate=5:1) to afford the target compound B-8-2 (10.0 g, 4.8% yield) as a yellow solid.

References

[1] Patent: WO2009/16460, 2009, A2. Location in patent: Page/Page column 75-76

6-bromo-2-methylimidazo[1,2-a]pyrimidine Preparation Products And Raw materials

Raw materials

2-Amino-5-bromopyrimidine Chloroacetone

Preparation Products

IMidazo[1,2-a]pyriMidine, 2-Methyl-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-

6-bromo-2-methylimidazo[1,2-a]pyrimidine Suppliers

Global( 36)Suppliers
Supplier Tel Email Country ProdList Advantage
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd. 		+86-029-86185165 +8618629664246 guoyuan@eastchinapharm.com China 1615 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Beijing Ouhe Technology Co., Ltd 010-010-82967028 13522913783 2355560935@qq.com China 12000 60
Shangchem Co., Ltd. +86-21-68182121 China 882 52
skychemical Co.Ltd 021-20958197 20965099 sales@skychemical.com China 1183 57
ShangHai AmK Pharmaceutical Technology Co., Ltd. 微信 17321281695 18019252918 sale@amkchem.com China 15136 55
Xi'an NewProChem Co.,Ltd. 15332490153 newprochem@126.com China 991 55
Shanghai Sainty Biotechnology Co., Ltd. 021-58957915 17721108391 907522080@qq.com China 997 55
skychemical Co.Ltd 021-20960837,QQ1332204249 sales@skychemical.com China 3341 55
Supplier Advantage
Jinan Carbotang Biotech Co.,Ltd. 		58
Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd. 		58
Amadis Chemical Company Limited 		58
Beijing Ouhe Technology Co., Ltd 60
Shangchem Co., Ltd. 52
skychemical Co.Ltd 57
ShangHai AmK Pharmaceutical Technology Co., Ltd. 55
Xi'an NewProChem Co.,Ltd. 55
Shanghai Sainty Biotechnology Co., Ltd. 55
skychemical Co.Ltd 55

6-bromo-2-methylimidazo[1,2-a]pyrimidine Spectrum

6-bromo-2-methylimidazo[1,2-a]pyrimidine(1111638-05-1)1HNMR
6-bromo-2-methylimidazo[1,2-a]pyrimidine IMidazo[1,2-a]pyriMidine, 6-broMo-2-Methyl- 6-Bromo-2-methylimidazo[1,2-a]pyrimidine 97% 6-fluoro-2-methylimidazo[1,2-a]pyrimidine 1111638-05-1