Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>MK-8245

MK-8245

MK-8245 Structure
MK-8245 structure
CAS No.
1030612-87-3
Chemical Name:
MK-8245
Synonyms
CS-116;MK-8245;MK8245 analog;MK-8245 analog;MK 8245 analog;MK-8245-analog;MK-8245 analog, 10 mM in DMSO;2-(5-(5-(4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)-2H-tetrazol-2-yl)ac;2-(5-(5-(4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)-2H-tetrazol-2-yl)aceti;5-[5-[4-(2-Bromo-5-fluorophenoxy)-1-piperidinyl]-1,3,4-thiadiazol-2-yl]-2H-tetrazole-2-acetic acid
CBNumber:
CB22539036
Molecular Formula:
C16H15BrFN7O3S
Molecular Weight:
484.3
MDL Number:
MFCD20039621
MOL File:
1030612-87-3.mol
Last updated:2025-07-16 20:18:59
Request For Quotation

MK-8245 Properties

FDA UNII 537E7QE8LX

MK-8245 price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation HCH0362795 2-(5-(5-(4-(2-BROMO-5-FLUOROPHENOXY)PIPERIDIN-1-YL)-1,3,4-THIADIAZOL-2-YL)-2H-TETRAZOL-2-YL)ACETIC ACID 95.00% 1030612-87-3 5MG $504.72 2021-12-16 Buy
Biorbyt Ltd orb146230 MK8245 >98% 1030612-87-3 100mg $690.2 2021-12-16 Buy
Matrix Scientific 094165 2-(5-(5-(4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)-2H-tetrazol-2-yl)acetic acid 95+% 1030612-87-3 250mg $950 2021-12-16 Buy
Biorbyt Ltd orb146230 MK8245 >98% 1030612-87-3 250mg $1356.6 2021-12-16 Buy
Matrix Scientific 094165 2-(5-(5-(4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)-2H-tetrazol-2-yl)acetic acid 95+% 1030612-87-3 1g $1995 2021-12-16 Buy
Product number Packaging Price Buy
HCH0362795 5MG $504.72 Buy
orb146230 100mg $690.2 Buy
094165 250mg $950 Buy
orb146230 250mg $1356.6 Buy
094165 1g $1995 Buy

MK-8245 Chemical Properties,Uses,Production

Uses

MK-8245 analog (compound 6) is a potent stearoyl-CoA desaturase (SCD) inhibitor with an IC50 of 7 nM for rat SCD. MK-8245 analog has antidiabetic and antidyslipidemic effects[1].

References

[1] Renata M Oballa, et al. Development of a liver-targeted stearoyl-CoA desaturase (SCD) inhibitor (MK-8245) to establish a therapeutic window for the treatment of diabetes and dyslipidemia. J Med Chem. 2011 Jul 28;54(14):5082-96. DOI:10.1021/jm200319u

MK-8245 Preparation Products And Raw materials

Raw materials

Preparation Products

MK-8245 Suppliers

Global( 68)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49733 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29804 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32376 58
Suzhou Victorypharm Co.,Ltd. 		+86-13916956214 sales@victory-pharm.com China 1299 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8467 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Shanghai HuanChuan Industry Co.,Ltd. 021-61478794 sales@hcshhai.com China 9793 50
AdooQ Bioscience CHINA 025-58849295 18951903616; info@adooq.cn China 2990 60
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 7972 62
Supplier Advantage
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
TargetMol Chemicals Inc. 		58
Suzhou Victorypharm Co.,Ltd. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Amadis Chemical Company Limited 		58
Shanghai HuanChuan Industry Co.,Ltd. 50
AdooQ Bioscience CHINA 60
ShangHai Biochempartner Co.,Ltd 62

View Lastest Price from MK-8245 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
MK-8245 analog pictures 2025-07-16 MK-8245 analog
1030612-87-3
 US $89.00-197.00 / mg 99.71% 10g TargetMol Chemicals Inc.
MK-8245 pictures 2020-01-13 MK-8245
1030612-87-3
 US $0.01 / KG 1KG 98%; 99% 500g； 1kg; 25kg Career Henan Chemical Co
  • MK-8245 analog pictures
  • MK-8245 analog
    1030612-87-3
  • US $89.00-197.00 / mg
  • 99.71%
  • TargetMol Chemicals Inc.
  • MK-8245 pictures
  • MK-8245
    1030612-87-3
  • US $0.01 / KG
  • 98%; 99%
  • Career Henan Chemical Co

MK-8245 Spectrum

MK-8245(1030612-87-3)1HNMR
MK-8245 2-(5-(5-(4-(2-bromo-5-fluorophenoxy)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)-2H-tetrazol-2-yl)acetic acid (5-{5-[4-(2-broMo-5-fluorophenoxy)piperidin-1-yl]-[1,3,4]-thiadiazol-2-yl}-2H-tetrazol-2-yl)acetic acid 5-[5-[4-(2-Bromo-5-fluorophenoxy)-1-piperidinyl]-1,3,4-thiadiazol-2-yl]-2H-tetrazole-2-acetic acid 2-(5-(5-(4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)-2H-tetrazol-2-yl)aceti 2-(5-(5-(4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)-2H-tetrazol-2-yl)ac CS-116 2H-Tetrazole-2-acetic acid, 5-[5-[4-(2-bromo-5-fluorophenoxy)-1-piperidinyl]-1,3,4-thiadiazol-2-yl]- MK 8245 analog MK8245 analog MK-8245 analog MK-8245-analog MK-8245 analog, 10 mM in DMSO 1030612-87-3 1030612-90 C16H15BrFN7O3S