ChemicalBook >> CAS DataBase List >>(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanoic Acid

(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanoic Acid

CAS No.
483340-19-8
Chemical Name:
(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanoic Acid
Synonyms
(αR;4-triazole-1-butanoic Acid;Isavuconazole interMediate 4;(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1;(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanoic Acid;(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic Acid;1H-1,2,4-Triazole-1-butanoic acid, β-(2,5-difluorophenyl)-β-hydroxy-α-methyl-, (αR,βR)-;(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanoic acid;(alphaR,betaR)-beta-(2,5-Difluorophenyl)-beta-hydroxy-alpha-methyl-1H-1,2,4-triazole-1-butanoic Acid
CBNumber:
CB22708856
Molecular Formula:
C13H13F2N3O3
Molecular Weight:
297.26
MDL Number:
MFCD28404610
MOL File:
483340-19-8.mol
Last updated:2023-04-23 13:52:06

(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanoic Acid Properties

Melting point 191-193 °C(Solv: methanol (67-56-1))
Boiling point 519.9±60.0 °C(Predicted)
Density 1.43±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DCM, Methanol
pka 3.89±0.23(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanoic Acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D446805 (αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoicAcid 483340-19-8 50mg $865 2021-12-16 Buy
Medical Isotopes, Inc. 50904 (αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoicAcid 483340-19-8 50mg $1285 2021-12-16 Buy
Ark Pharm AK205096 (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanoicacid 95+% 483340-19-8 1g $149 2021-12-16 Buy
Crysdot CD11117712 (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanoicacid 95+% 483340-19-8 100mg $515 2021-12-16 Buy
Ambeed A106080 (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanoicacid 95% 483340-19-8 5g $524 2021-12-16 Buy
Product number Packaging Price Buy
D446805 50mg $865 Buy
50904 50mg $1285 Buy
AK205096 1g $149 Buy
CD11117712 100mg $515 Buy
A106080 5g $524 Buy

(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanoic Acid Chemical Properties,Uses,Production

Uses

(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic Acid is an intermediate in the synthesis of Isavuconazole (I777830), an triazole based antifungal agent for the treatment of invasive fungal infections.

(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanoic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 51)Suppliers
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Chembon Pharmaceutical Co., Ltd.
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ATK CHEMICAL COMPANY LIMITED
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Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Shanghai Hao Yun Chemical Science Co.,Ltd. 021-68367562 15002147577; sales@haoyunchem.com China 489 55
(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanoic Acid Isavuconazole interMediate 4 (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanoic acid 4-triazole-1-butanoic Acid (alphaR,betaR)-beta-(2,5-Difluorophenyl)-beta-hydroxy-alpha-methyl-1H-1,2,4-triazole-1-butanoic Acid 1H-1,2,4-Triazole-1-butanoic acid, β-(2,5-difluorophenyl)-β-hydroxy-α-methyl-, (αR,βR)- (αR (αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1 (αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic Acid 483340-19-8