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R-(+)-ETOMOXIR

Description Application
R-(+)-ETOMOXIR
R-(+)-ETOMOXIR structure
CAS No.
124083-20-1
Chemical Name:
R-(+)-ETOMOXIR
Synonyms
CS-1432;S-(+)-ETOMOXIR;R-(+)-ETOMOXIR;Etomoxir fandachem;R(+)-Etomoxir free acid;R-(+)-ETOMOXIR USP/EP/BP;ethyl (2S)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylate;(R)-2-[6-(4-CHLOROPHENOXY)HEXYL]OXIRANECARBOXYLIC ACID, ETHYL ESTER;(S)-2-[6-(4-CHLOROPHENOXY)HEXYL]OXIRANECARBOXYLIC ACID, ETHYL ESTER;(R)-2-[6-(4-Chlorophenoxy)hexyl]oxirane-2-carboxylic acid ethyl ester
CBNumber:
CB2407236
Molecular Formula:
C17H23ClO4
Formula Weight:
326.82
MOL File:
124083-20-1.mol

R-(+)-ETOMOXIR Properties

Melting point:
32-34°C
Boiling point:
405.0±25.0 °C(Predicted)
Density 
1.163
storage temp. 
Inert atmosphere,2-8°C

R-(+)-ETOMOXIR Chemical Properties,Uses,Production

Description

Etomoxir, or 2[6(4-chlorophenoxy)hexyl]oxirane-2-carboxylate, is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) on the outer face of the inner mitochondrial membrane.This prevents the formation of acyl carnitines, a step that is necessary for the transport of fatty acyl chains from the cytosol into the intermembrane space of the mitochondria. This step is essential to the production of ATP from fatty acid oxidation. Etomoxir has also been identified as a direct agonist of PPARα. An off-target effect has been demonstrated at high concentrations of etomoxir on Coenzyme-A (CoA) metabolism.

Application

Etomoxir ((R)-(+)-Etomoxir) is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig.

Chemical Properties

Colourless Oil

Uses

An inhibitor of carnitine palmitoyltransferase A (CPT1), which is required for the oexidation of long-chain acyl CoA esters. A strong inhibitor of mitochondrial CPT1 and is a candidate as an anti-diabetic drug

R-(+)-ETOMOXIR Preparation Products And Raw materials

Raw materials

Preparation Products


R-(+)-ETOMOXIR Suppliers

Global( 67)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 968 58
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 8882 55
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com CHINA 47496 58
career henan chemical co
13203830695 0086-371-86658258
0086-371-86658258 factory@coreychem.com CHINA 29865 58
Zhuozhou Wenxi import and Export Co., Ltd
+8613111626072 (WhatsApp)
Wechat: +8613111626072 Wickr me: waynehu zzwenxi@126.com CHINA 13187 58
Hubei Ipure Biology Co., Ltd
+8618062405514
18062427325 ada@ipurechemical.com;ada@ipurechemical.com China 6031 58
HONG KONG IPURE BIOLOGY CO.,LIMITED
18062405514 86 18062405514
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HANGZHOU CLAP TECHNOLOGY CO.,LTD
13588875226 86-571-88216897、88216896
86-571-88216895 sales@hzclap.com CHINA 6469 58
Dideu Industries Group Limited
029-88380327
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Baoji Guokang Bio-Technology Co., Ltd.
09173909592
09173909592 cngksw@aliyun.com CHINA 9446 58

Related articles

  • Biological activity of Etomoxir
  • Etomoxir ((R)-(+)-Etomoxir) is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid ox....
  • Oct 29,2019

View Lastest Price from R-(+)-ETOMOXIR manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-07-13 Etomoxir
124083-20-1
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
2021-07-10 Etomoxir
124083-20-1
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
2020-01-13 Etomoxir
124083-20-1
US $1.00 / g 1g 95-99% 1ton Career Henan Chemical Co

124083-20-1(R-(+)-ETOMOXIR)Related Search:


  • (R)-2-[6-(4-Chlorophenoxy)hexyl]oxirane-2-carboxylic acid ethyl ester
  • 2-Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, ethyl ester, (2R)-
  • (2S)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylic acid ethyl ester
  • ethyl (2S)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylate
  • (2R)-2-[6-(4-Chlorophenoxy)hexyl]-2-oxiranecarboxylic acid ethyl ester
  • 2-Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, ethyl ester, (2R)-(R)-(+)-Etomoxir
  • S-(+)-ETOMOXIR
  • (S)-2-[6-(4-CHLOROPHENOXY)HEXYL]OXIRANECARBOXYLIC ACID, ETHYL ESTER
  • R-(+)-ETOMOXIR
  • (R)-2-[6-(4-CHLOROPHENOXY)HEXYL]OXIRANECARBOXYLIC ACID, ETHYL ESTER
  • R(+)-Etomoxir free acid
  • CS-1432
  • Etomoxir fandachem
  • R-(+)-ETOMOXIR USP/EP/BP
  • 124083-20-1
  • Chiral Reagents
  • Inhibitors
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