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ChemicalBook >> CAS DataBase List >>1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT

1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT

1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT Structure
1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT structure
CAS No.
1628353-02-5
Chemical Name:
1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT
Synonyms
PTDINS-(3,4,5)-P3 (1,2-DIPALMITOYL) SODIUM SALT;PHOSPHATIDYLINOSITOL-3,4,5-TRIPHOSPHATE C-16 SODIUM SALT;1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT
CBNumber:
CB2675372
Molecular Formula:
C41H83NaO22P4
Molecular Weight:
1074.98
MDL Number:
MFCD05863537
MOL File:
Mol file
Last updated:2023-05-21 10:59:17
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1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT Properties

storage temp. Store at -20°C
solubility CHCl3:CH3OH:H2O (2.5:3:1): 3.8 mg/ml; PBS (pH 7.2): 10 mg/ml
form A lyophilized powder

1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 64920 PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) ≥98% 1628353-02-5 100μg $47 2024-03-01 Buy
Cayman Chemical 64920 PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) ≥98% 1628353-02-5 500μg $206 2024-03-01 Buy
Cayman Chemical 64920 PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) ≥98% 1628353-02-5 1mg $360 2024-03-01 Buy
Cayman Chemical 64920 PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) ≥98% 1628353-02-5 5mg $1570 2024-03-01 Buy
AK Scientific 3144EL Tetrasodium;[(1R,2S,4S,5S)-3-[[(2R)-2,3-di(hexadecanoyloxy)propoxy]-oxidophosphoryl]oxy-2,4-dihydroxy-5,6-bis[[hydroxy(oxido)phosphoryl]oxy]cyclohexyl]hydrogenphosphate 1628353-02-5 1mg $499 2021-12-16 Buy
Product number Packaging Price Buy
64920 100μg $47 Buy
64920 500μg $206 Buy
64920 1mg $360 Buy
64920 5mg $1570 Buy
3144EL 1mg $499 Buy

1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT Chemical Properties,Uses,Production

Description

The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.1,2 PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins.3,4 Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. For further reading on inositol phospholipids, see also references 5 and 6.

References

1. Lapetina, E.G., Billah, M.M., and Cuatrecasas, P. The phosphatidylinositol cycle and the regulation of arachidonic acid production Nature 292,367-369(1981).
2. Majerus, P.W. Inositol phosphate biochemistry Annu. Rev. Biochem. 61,225-250(1992).
3. Tanaka, K., Imajoh-Ohmi, S., Sawada, T., et al. A target of phosphatidylinositol 3,4,5-trisphosphate with a zinc finger motif similar to that of the ADP-ribosylation-factor GTPase-activating protein and two pleckstrin homology domains Eur. J. Biochem. 245,512-519(1997).
4. Yang, X., Rudolf, M., Carew, M.A., et al. Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate J. Biol. Chem. 274(27),18973-18980(1999).
5. Pike, L.J., and Casey, L. Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domains J. Biol. Chem. 271,26453-26456(1996).
6. Berridge, M.J. Inositol trisphosphate and calcium signalling Nature 361(6410),315-325(1993).

1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT Preparation Products And Raw materials

Raw materials

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1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT Suppliers

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Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai Universal Biotech Co.,Ltd 18768175414 gaojun@univ-bio.com China 24998 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
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Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Universal Biotech Co.,Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
1-(1,2R-DIHEXADECANOYLPHOSPHATIDYL)INOSITOL-3,4,5-TRIPHOSPHATE, HEXASODIUM SALT PHOSPHATIDYLINOSITOL-3,4,5-TRIPHOSPHATE C-16 SODIUM SALT PTDINS-(3,4,5)-P3 (1,2-DIPALMITOYL) SODIUM SALT 1628353-02-5