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I-SAP

CAS No.
133538-58-6
Chemical Name:
I-SAP
Synonyms
I-SAP;I SAP,ISAP;THROMBOXANE A2;SZNMERGTFJHNSM-JAWYFFTGSA-N;IODOPHENYL SULFONYL AMINO PINANE;7-(6,6-dimethyl-3-(4-iodobenzenesulfonylamino)bicyclo(3.1.1.)hept-2-yl)-5-heptenoic acid;5-Heptenoic acid, 7-[(1S,2S,3S,5R)-3-[[(4-iodophenyl)sulfonyl]amino]-6,6-dimethylbicyclo[3.1.1]hept-2-yl]-, (5Z)-;[3S-[1alpha,3beta-5alpha]]-7-[3-[[(4-Ifodophenyl)sulfonyl]amino]-6,6-dimethylbicyclo[3.1.1]hept-2-yl]-5Z-heptenoic acid;[3S-[1ALPHA,2ALPHA,3BETA-5ALPHA]]-7-[3-[[(4-IODOPHENYL)SULFONYL]AMINO]-6,6-DIMETHYLBICYCLO[3.1.1]HEPT-2-YL]-5Z-HEPTENOIC ACID
CBNumber:
CB2736538
Molecular Formula:
C22H30INO4S
Molecular Weight:
531.45
MDL Number:
MFCD00216083
MOL File:
133538-58-6.mol
Last updated:2025-07-21 13:20:27
Product description Number Pack Size Price
I-SAP ≥98% 19021 100μg $73
I-SAP ≥98% 19021 500μg $324
I-SAP ≥98% 19021 1mg $575
I-SAP 1803AH 1mg $737
[3S-[1ALPHA,3BETA-5ALPHA]]-7-[3-[[(4-IODOPHENYL)SULFONYL]AMINO]-6,6-DIMETHYLBICYCLO[3.1.1]HEPT-2-YL]-5Z-HEPTENOIC ACID 98.00% CHM0290099 1MG $1097.25

I-SAP Properties

Boiling point 606.3±61.0 °C(Predicted)
Density 1.51±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: >50 mg/ml (from Pinane TXA2); DMSO: >25 mg/ml (from Pinane TXA2); Ethanol: >100 mg/ml (from Pinane TXA2); PBS pH 7.2: >100 μg/ml (from Pinane TXA2)
pka 4.76±0.10(Predicted)
FDA UNII 4C2A5G825S

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

I-SAP price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 19021 I-SAP ≥98% 133538-58-6 100μg $73 2024-03-01 Buy
Cayman Chemical 19021 I-SAP ≥98% 133538-58-6 500μg $324 2024-03-01 Buy
Cayman Chemical 19021 I-SAP ≥98% 133538-58-6 1mg $575 2024-03-01 Buy
AK Scientific 1803AH I-SAP 133538-58-6 1mg $737 2021-12-16 Buy
American Custom Chemicals Corporation CHM0290099 [3S-[1ALPHA,3BETA-5ALPHA]]-7-[3-[[(4-IODOPHENYL)SULFONYL]AMINO]-6,6-DIMETHYLBICYCLO[3.1.1]HEPT-2-YL]-5Z-HEPTENOIC ACID 98.00% 133538-58-6 1MG $1097.25 2021-12-16 Buy
Product number Packaging Price Buy
19021 100μg $73 Buy
19021 500μg $324 Buy
19021 1mg $575 Buy
1803AH 1mg $737 Buy
CHM0290099 1MG $1097.25 Buy

I-SAP Chemical Properties,Uses,Production

Uses

I-SAP is a radioiodinated TXA2/PGH2 receptor antagonist. The bind between I-SAP and the receptors, is inhibited by the histidine modifying reagent diethyl-pyrocarbonate (DEPC)[1][2].

IC 50

TXA2 Receptor

References

[1] Saussy DL Jr, et al. Binding of a novel radioiodinated thromboxane A2/prostaglandin H2 antagonist to guinea pig lung membranes. Eicosanoids. 1992;5(1):1-4. PMID:1419073
[2] Schr?r K, et al. Inhibition of ligand binding to thromboxane A2/prostaglandin H2 receptors by diethylpyrocarbonate. Protection by receptor ligands and reversal by hydroxylamine. Biochem Pharmacol. 1995 Mar 30;49(7):921-7. DOI:10.1016/0006-2952(95)00015-r

I-SAP Preparation Products And Raw materials

Raw materials

Preparation Products

I-SAP Suppliers

Global( 34)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8140 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24961 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Cayman Chemical Company 800-364-9897 sales@caymanchem.com China 6838 58
Biosynth Biological Technology (Suzhou) Co Ltd 51288865780 sales@biosynth.com China 6051 58
Guangzhou Biopark Technology Co., Ltd. 020-83808789 CHINA 179 58
Chongqing Boer Biotechnology Co., Ltd. 13251428727, 13368356747 CHINA 157 58

View Lastest Price from I-SAP manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
I-SAP pictures 2025-07-20 I-SAP
133538-58-6
US $0.00 / mg 10g TargetMol Chemicals Inc.
  • I-SAP pictures
  • I-SAP
    133538-58-6
  • US $0.00 / mg
  • TargetMol Chemicals Inc.
THROMBOXANE A2 I-SAP IODOPHENYL SULFONYL AMINO PINANE [3S-[1ALPHA,2ALPHA,3BETA-5ALPHA]]-7-[3-[[(4-IODOPHENYL)SULFONYL]AMINO]-6,6-DIMETHYLBICYCLO[3.1.1]HEPT-2-YL]-5Z-HEPTENOIC ACID [3S-[1alpha,3beta-5alpha]]-7-[3-[[(4-Ifodophenyl)sulfonyl]amino]-6,6-dimethylbicyclo[3.1.1]hept-2-yl]-5Z-heptenoic acid 7-(6,6-dimethyl-3-(4-iodobenzenesulfonylamino)bicyclo(3.1.1.)hept-2-yl)-5-heptenoic acid SZNMERGTFJHNSM-JAWYFFTGSA-N I SAP,ISAP 5-Heptenoic acid, 7-[(1S,2S,3S,5R)-3-[[(4-iodophenyl)sulfonyl]amino]-6,6-dimethylbicyclo[3.1.1]hept-2-yl]-, (5Z)- 133538-58-6 C22H30INO4S