ChemicalBook >> CAS DataBase List >>1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
- CAS No.
- 70641-51-9
- Chemical Name:
- 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
- Synonyms
- EDELFOSINE;ET-18-OCH3;ET-18-OCH?;Ro 14-5243;NSC 343649;NSC 324368;SN-ET-18-OCH3;18:0-1:0 DIETHER PC;2-O-METHYL PAF C-18;innersalt,4-oxide,(+-)-hydroxide
- CBNumber:
- CB2768197
- Molecular Formula:
- C27H58NO6P
- Molecular Weight:
- 523.74
- MDL Number:
- MFCD00063527
- MOL File:
- 70641-51-9.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
| storage temp. | -20°C |
|---|---|
| solubility | ethanol: 15 mg/mL at 45 °C, soluble |
| form | waxy solid |
| color | white |
| Water Solubility | Soluble to 20 mM in water |
| FDA UNII | 1Y6SNA8L5S |
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 |
|---|---|
| WGK Germany | 3 |
| RTECS | YK0718000 |
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0332 | Edelfosine ≥95% (HPLC) | 70641-51-9 | 5mg | $144 | 2024-03-01 | Buy |
| Sigma-Aldrich | 341207 | ET-18-OCH? | 70641-51-9 | 5mg | $144 | 2024-03-01 | Buy |
| Sigma-Aldrich | O9262 | 1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphorylcholine ≥99% (TLC), waxy solid | 70641-51-9 | 5mg | $141 | 2022-05-15 | Buy |
| Sigma-Aldrich | SML0332 | Edelfosine ≥95% (HPLC) | 70641-51-9 | 25mg | $568 | 2024-03-01 | Buy |
| Usbiological | 448513 | ET-18-OCH3 | 70641-51-9 | 5mg | $305 | 2021-12-16 | Buy |
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties,Uses,Production
Uses
Edelfosine has been used to treat human lung carcinoma A549 cells and study its effects on tuftelin 1 (TUFT1) expression. It is also used to evaluate the cell growth of MCF-7/M cells.
Definition
ChEBI: 1-octadecyl-2-methylglycero-3-phosphocholine is a glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.
General Description
Edelfosine has anti-inflammatory, anti-autoimmune, antiparasitic and anti-viral properties. It stimulates eryptosis by cell shrinkage and cell membrane scrambling.
Biochem/physiol Actions
Edelfosine is a synthetic alkyl-lisophospholipid with anti-tumor activity. The compound induces apoptosis in a variety of cancer cells. Edelfosine accumulates in the cell membrane, where it alters lipid composition and induces the co-clustering of lipid rafts and Fas/CD95 death receptor.
storage
Store at -20°C
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Suppliers
Global( 23)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
| Synchem OHG | +49 5662 408730 | info@synchem.de | Germany | 4708 | 70 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Creative Peptides | info@creative-peptides.com | United States | 6084 | 56 | |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-61109150 | sales@tcisct.com | China | 31183 | 58 |
| Supplier | Advantage |
|---|---|
| Nextpeptide Inc | 58 |
| J & K SCIENTIFIC LTD. | 76 |
| Chemsky (shanghai) International Co.,Ltd | 60 |
| Synchem OHG | 70 |
| Sigma-Aldrich | 80 |
| Creative Peptides | 56 |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 58 |
70641-51-9(1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE)Related Search:
1,2-DISTEAROYL-D70-3-SN-GLYCEROPHOSPHATIDYLCHOLINE
1-OCTADECANOYL-2-[(CIS,CIS,CIS,CIS)-5,8,11,14-EICOSATETRAENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE
1,2-Distearoyl-sn-glycero-3-phosphocholine
1,2-DIEICOSANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1-STEAROYL-2-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1,2-DINONADECANOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE
EDELFOSINE,1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1,2-O-DIOCTADECYL-RAC-GLYCERO-3-PHOSPHOCHOLINE
1-stearoyl-2-linoleoylphosphatidylcholine
1of4
4-Hydroxy-7-methoxy-N,N,N-trimethyl-3,5,9-Trioxa-4-phosphaheptacosan-1-aminium 4-oxide
NSC 324368
NSC 343649
Racemic 1-O-octadecyl-2-O-methylglycero-3-phosphocholine
Ro 14-5243
ET-18-OCH?
ET-18-OCH3
EDELFOSINE
18:0-1:0 DIETHER PC
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
2-O-METHYL PAF C-18
3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide
SN-ET-18-OCH3
3,5,9-trioxa-4-phosphaheptacosan-1-aminium,4-hydroxy-7-methoxy-n,n,n-trimethyl
innersalt,4-oxide,(+-)-hydroxide
rac-1-octadecyl-2-methoxyglycero-3-phosphocholine
(2-methoxy-3-octadecoxy-propyl) 2-(trimethylazaniumyl)ethyl phosphate
(2-methoxy-3-octadecoxypropyl) 2-(trimethylazaniumyl)ethyl phosphate
(2-methoxy-3-stearyloxy-propyl) 2-(trimethylammonio)ethyl phosphate
Edelfosine, ALP, Ro 14-5243, ET-18-OMe, ET 18-OCH3, NSC 324368, NSC 343649
1-Octadecyl-2-methylglycero-3-phosphorylcholine
ET-18-OCH - CAS 70641-51-9 - Calbiochem
70641-51-9
C27H58NO6P