thenyldiamine
- CAS No.
- 91-79-2
- Chemical Name:
- thenyldiamine
- Synonyms
- Thefanil;Tenfidil;WIN-2848;Thenfadil;thenyldiamine;thenyldiamine USP/EP/BP;Thenyldiamine Hydrochloride (Thenfadil);N,N-dimethyl-N-2-pyridyl-N-3-thenylethylenediamine;2-dimethylaminoethyl-(2-pyridyl)-(3-thienylmethyl)amine;N,N-Dimethyl-N'-(2-pyridinyl)-N'-(3-thienylmethyl)-1,2-ethanediamine
- CBNumber:
- CB2875794
- Molecular Formula:
- C14H19N3S
- Molecular Weight:
- 261.39
- MDL Number:
- MFCD00242574
- MOL File:
- 91-79-2.mol
- MSDS File:
- SDS
| Boiling point | bp1.0 169-172° |
|---|---|
| Density | 1.1388 (rough estimate) |
| refractive index | nD20 1.5915 |
| pka | pKa 3.94(H2O t=25 c=0.002 to 0.01) (Uncertain);8.93 (Uncertain) |
| Water Solubility | 4.444g/L(37.5 ºC) |
| FDA UNII | E4U52363JE |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
thenyldiamine Chemical Properties,Uses,Production
Chemical Properties
Liquid.
Originator
Thenyldiamine,ZYF Pharm Chemical
Uses
Medicine (as base for various salts, especially the hydrochloride).
Definition
ChEBI: Thenyldiamine is a dialkylarylamine and a tertiary amino compound.
Manufacturing Process
To a suspension of 3.12 g of sodium amide in 50 ml dry toluene was added
dropwise 12 g of 2-(dimethylamino)ethylaminopyridine. The mixture was
refluxed for 2 hours, cooled to 50°C, and 21 g 3-thenyl bromide was added
dropwise. When reaction subsided, the brownish-orange mixture was refluxed
for 0.5 hour, cooled, and poured into 150 ml of water. The toluene layer was
separated, extracted with 5% hydrochloric acid. This extract was saturated
with potassium carbonate. The free base was extracted with ether, dried and
fractionated. Yield of N,N-dimethyl-N'-2-pyridinyl-N'-(3-thienylmethyl)-1,2-
ethanediamine 31%, boiling point 169-172°C/1 mm.
106 g of the free base was dissolved in 500 ml of isopropyl alcohol and 34 ml
concentrated hydrochloric acid was added. After shaking, the reaction mixture
was allowed to added. After through cooling in an ice-methanol mixture, the
salt was collected and washed on the filter with low boiling petroleum ether,
Melting point of N,N-dimethyl-N'-2-pyridinyl-N'-(3-thienylmethyl)-1,2-
ethanediamine hydrochloride 169.5-170°C.
Therapeutic Function
Antihistaminic
thenyldiamine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-18612256290 | 1056@dideu.com | China | 3791 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29474 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 9309 | 58 |
| Nanjing Xinmeihe Pharmaceutical Co., Ltd. | 025-57672321 13739186949 | 2548785915@qq.com | China | 222 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 029-81124267 15229202216 | 1073@dideu.com | China | 10011 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 15229059051 | 1027@dideu.com | China | 9926 | 58 |
| Shanghai YuZn Pharm. Technology Co.,Ltd. | 15921286451; 15921286451 | 2010681527@qq.com | China | 5077 | 58 |
View Lastest Price from thenyldiamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-20 | Thenyldiamine
91-79-2
|
US $1.00-1.00 / KG | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2021-06-17 | thenyldiamine USP/EP/BP
91-79-2
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited |
-
- Thenyldiamine
91-79-2
- US $1.00-1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- thenyldiamine USP/EP/BP
91-79-2
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited