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Gadobutrol

Gadobutrol structure

CAS No.: 138071-82-6

Chemical Name:: Gadobutrol

Synonyms: CL124;CS-113;gudobutrol;Gadobutrol;Gsdobutrol;Ggadobutrol;Gadobutrol Monomer;gadolinium butanol;Gadolinium cloth alcohol;Lansoprazole Impurity 76

CBNumber:: CB31118291

Molecular Formula:: C18H31N4O9.Gd

Molecular Weight:: 604.712

MDL Number:: MFCD00911649

MOL File:: 138071-82-6.mol

Last updated:2024-04-09 13:47:46

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Gadobutrol Properties

Melting point	>264°C (dec.)
Density	1.3 g/mL at 37 °C
storage temp.	Refrigerator
solubility	Water (Slightly)
form	Solid
color	White to Off-White
PH	6.6-8
InChIKey	ZPDFIIGFYAHNSK-IWEVFNEWNA-K
SMILES	N1(CCN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC([O-])=O)CC1)[C@H](CO)[C@H](O)CO.[Gd+3] \|&1:24,27,r\|
FDA UNII	1BJ477IO2L
NCI Drug Dictionary	gadobutrol
ATC code	V08CA09

SAFETY

Risk and Safety Statements

Toxicity	LD50 i.v. in mice: 23 mmol/kg (Vogler)

Gadobutrol price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	451035	Gadobutrol	138071-82-6	250mg	$355	2021-12-16	Buy

Product number	Packaging	Price	Buy
451035	250mg	$355	Buy

Gadobutrol Chemical Properties,Uses,Production

Uses

Gadobutrol is a gadolinium-based MRI contrast agent (GBCA).

Uses

Gadobutrol injection is a magnetic resonance imaging (MRI) contrast agent that is used to help create a clear picture of the body during an MRI scan. MRI scans are a special kind of procedure that lets a doctor look at the inside of the body, such as the brain.

brand name

Gadobutrol is marketed by Bayer AG as Gadovist, and by Bayer HealthCare Pharmaceuticals as Gadavist. In India, it is also marketed by Vivere Imaging as Viv-butrol.

Mechanism of action

In the central nervous system, Gadobutrol works by highlighting any areas with disrupted blood brain barrier (BBB) and/or abnormal vascularity. In breast tissue, Gadobutrol exposes the presence and extent of malignant breast disease.

Side effects

Side effects of Gadobutrol are uncommon but may include: headache, nausea, vomiting, feeling unwell (malaise), dizziness, abnormal or unpleasant taste in your mouth, feeling hot, numbness or tingly feeling, itching or rash, skin redness, or injection site reactions (cold feeling, warmth, pain, or burning). Its more serious side effects include: urinating less than usual or not at all; drowsiness, confusion, mood changes, increased thirst, loss of appetite; swelling, weight gain, shortness of breath; seizures (convulsions); breathing problems; pounding heartbeats or fluttering in your chest; or severe pain, burning, or irritation around the IV needle.

Dosage

Gadobutrol is given as an infusion into a vein. The recommended dose of Gadobutrol for adult and pediatric patients (including term neonates) is 0.1 mL/kg body weight (0.1 mmol/kg).

Waste Disposal

Expired or waste pharmaceuticals shall carefully take into consideration applicable DEA, EPA, and FDA regulations. It is not appropriate to dispose by flushing the pharmaceutical down the toilet or discarding to trash. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator.

Gadobutrol Preparation Products And Raw materials

Raw materials

Preparation Products

Gadobutrol Suppliers

Global( 181)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58
HAINAN POLY PHARMCEUTICAL CO. LTD	+86-0571-89385087 +8613616530509	ff@hnpoly.com	China	118	58
Zouping mingyuan import & export trading co., ltd	+86-0543-2240078 +8618364991597	myzhao793@163.com	China	994	58
Xilinglab Co., Ltd.	+8618381337976	bd@xilinglab.com	China	86	58
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	16801	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21689	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58

Supplier	Advantage
AFINE CHEMICALS LIMITED	58
HAINAN POLY PHARMCEUTICAL CO. LTD	58
Zouping mingyuan import & export trading co., ltd	58
Xilinglab Co., Ltd.	58
BOC Sciences	58
Henan Fengda Chemical Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Chongqing Chemdad Co., Ltd	58

View Lastest Price from Gadobutrol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-09	Gadobutrol 138071-82-6	US $8.00-1.00 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2023-06-26	Gadobutrol 138071-82-6	US $200.00 / kg	1kg	99%	1000kg/Month	Hebei Mingeng Biotechnology Co., Ltd
2023-06-26	Gadobutrol 138071-82-6	US $0.00 / kg	1kg	99%	20tons	Zouping mingyuan import & export trading co., ltd

Gadobutrol
138071-82-6
US $8.00-1.00 / KG
99%
Henan Fengda Chemical Co., Ltd

Gadobutrol
138071-82-6
US $200.00 / kg
99%
Hebei Mingeng Biotechnology Co., Ltd

Gadobutrol
138071-82-6
US $0.00 / kg
99%
Zouping mingyuan import & export trading co., ltd

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1,1,4,7,10,10-HEXAMETHYLTRIETHYLENETETRAMINE

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Gadobutrol GadoliniuM,[10-[2,3-dihydroxy-1-(hydroxyMethyl)propyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-)-kN1,kN4,kN7,kN10,kO1,kO4,kO7]- gallium 10-(1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-tricarboxylate CL124 gadolinium(III) 2,2',2''-(10-((2R,3S)-1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate CS-113 gudobutrol Ggadobutrol Gsdobutrol Gadolinium cloth alcohol Gadobutrol Monomer Lansoprazole Impurity 76 gadolinium butanol 138071-82-6 C18H31GdN4O9 C18H31GaN4O9 API