MK-677
- CAS No.
- 159634-47-6
- Chemical Name:
- MK-677
- Synonyms
- MK-677;Ibutamoren;Mk677 Sarms;IbutaMoren (MK-677);L 163191;MK-0677;MK-677;IBUTAMOREN (MK-677), CID178024;Ibutamoren,MK-677, MK-0677, L-163,191;Ibutamoren mesylate (MK-0667, L163191);(R)-2-amino-N-(3-(benzyloxy)-1-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidin]-1'-yl)-1-oxopropan-2-yl)-2-methylpropanamide;2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide
- CBNumber:
- CB31178916
- Molecular Formula:
- C27H36N4O5S
- Molecular Weight:
- 528.66
- MDL Number:
- MFCD00867473
- MOL File:
- 159634-47-6.mol
- MSDS File:
- SDS
| Density | 1.32 |
|---|---|
| pka | 15.73±0.46(Predicted) |
| InChIKey | UMUPQWIGCOZEOY-JOCHJYFZSA-N |
| SMILES | C(N[C@H](COCC1=CC=CC=C1)C(N1CCC2(CC1)C1=C(N(S(C)(=O)=O)C2)C=CC=C1)=O)(=O)C(N)(C)C |
| FDA UNII | GJ0EGN38UL |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 |
MK-677 Chemical Properties,Uses,Production
Description
Ibutamoren (INN) (developmental code names MK-677, MK-0677, L-163,191)is a non-peptidic, potent, long acting, orally-active, and selective agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin.
It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including GH and insulin-like growth factor 1 (IGF-1), but without affecting cortisol levels. MK677 has shown to sustain activation of GH-IGF-1 Axis and increase in lean body mass but no change in total fat mass or visceral fat.
It is currently under development as a potential treatment for reduced levels of these hormones, such as in children or elderly adults with growth hormone deficiency, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly.
Uses
Growth hormone releasing factor.
benefits
The benefits of MK-677 include muscle-building, a reduction in muscle wasting, better bone density, improved sleep, and anti-aging properties. It may also have nootropic effects and it can be beneficial in treating growth hormone deficiencies.
Side effects
Side effects of MK-677 are typically the result of unnaturally high levels of growth hormone in the body from taking too much too often, which include:
Increased appetite
Lethargy
Joint pain if you have previous medical conditions or elevated hormone levels
Insulin resistance
Possible increase in prolactin levels.
Safety
Ibutamoren is a muscle building anabolic compound. It's considered safe if you don't have high blood glucose level and if you don't suffer from congestive heart failure. It's considered a boon for anti aging and it's a life longevity material. It's considered to be more beneficial than to be harmful. The optimal dose for body building is to take 25mg at bedtime for four to six weeks. It is a water retaining compound so beware of bloating.
MK-677 Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Cell Pharmaceutical Co., Ltd | +86-13129979210 +86-13129979210 | sales@cellwh.com | China | 376 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 951 | 58 |
| CONTIDE BIOTECH CO.,LTD | +85253358525 | xena@healthtide-api.com | China | 499 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 6710 | 58 |
| Henan Tengmao Chemical Technology Co. LTD | +8615238638457 | salesvip2@hntmhg.com | China | 415 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 616 | 58 |
| ARCTIC EXPORTS INC | +1-3026880818 +1-3026880818 | ARCTICEXPORTSINC@GMAIL.COM | Canada | 68 | 58 |
| Sigma Audley | +86-18336680971 +86-18126314766 | nova@sh-teruiop.com | China | 525 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
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View Lastest Price from MK-677 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-27 | Ibutamoren；MK-677
159634-47-6
|
US $1.00 / g | 1g | 99% | 100kg | Wuhan Cell Pharmaceutical Co., Ltd | |
 |
2024-04-26 | Ibutamoren
159634-47-6
|
US $30.00 / kg | 1kg | 99% | 10000kg | hebei hongtan Biotechnology Co., Ltd | |
 |
2024-03-08 | lbutamoren
159634-47-6
|
US $10.00 / kg | 1kg | 99% | 1000kg | Nantong Guangyuan Chemicl Co,Ltd |
-
- Ibutamoren；MK-677
159634-47-6
- US $1.00 / g
- 99%
- Wuhan Cell Pharmaceutical Co., Ltd
-
- Ibutamoren
159634-47-6
- US $30.00 / kg
- 99%
- hebei hongtan Biotechnology Co., Ltd
-
- lbutamoren
159634-47-6
- US $10.00 / kg
- 99%
- Nantong Guangyuan Chemicl Co,Ltd