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H-SER-PHE-LEU-LEU-ARG-OH

CAS No.
141685-53-2
Chemical Name:
H-SER-PHE-LEU-LEU-ARG-OH
Synonyms
SFLLR;SER-PHE-LEU-LEU-ARG;H-SER-PHE-LEU-LEU-ARG-OH;Thrombin Receptor Activator for Peptide 5 (TRAP-5);L-Seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginine;L-Arginine, L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-;SFLLR, Coagulation Factor II Receptor (1-5) (huMan), PAR-1 (1-5) (huMan), ThroMbin Receptor (1-5) (huMan), ThroMbin Receptor Activator Peptide 5, Proteinase Activated Receptor 1 (1-5) (huMan)
CBNumber:
CB3151835
Molecular Formula:
C30H50N8O7
Molecular Weight:
634.77
MDL Number:
MFCD00238174
MOL File:
141685-53-2.mol
Last updated:2023-05-18 11:30:58

H-SER-PHE-LEU-LEU-ARG-OH Properties

Density 1.32±0.1 g/cm3(Predicted)
storage temp. -15°C
solubility insoluble in EtOH; ≥14.63 mg/mL in H2O; ≥63.5 mg/mL in DMSO
form solid
pka 3.34±0.10(Predicted)

H-SER-PHE-LEU-LEU-ARG-OH price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ApexBio Technology A1036 ThrombinReceptorActivatorforPeptide5(TRAP-5) 141685-53-2 5mg $45 2021-12-16 Buy
ApexBio Technology A1036 ThrombinReceptorActivatorforPeptide5(TRAP-5) 141685-53-2 10mg $75 2021-12-16 Buy
ChemScene CS-0044800 ThrombinReceptorActivatorforPeptide5TRAP-5 141685-53-2 1mg $80 2021-12-16 Buy
ApexBio Technology A1036 ThrombinReceptorActivatorforPeptide5(TRAP-5) 141685-53-2 25mg $105 2021-12-16 Buy
ChemScene CS-0044800 ThrombinReceptorActivatorforPeptide5TRAP-5 141685-53-2 5mg $180 2021-12-16 Buy
Product number Packaging Price Buy
A1036 5mg $45 Buy
A1036 10mg $75 Buy
CS-0044800 1mg $80 Buy
A1036 25mg $105 Buy
CS-0044800 5mg $180 Buy

H-SER-PHE-LEU-LEU-ARG-OH Chemical Properties,Uses,Production

Biological Activity

thrombin receptor activator for peptide 5 (trap-5),(c30h50n8o7), a peptide with the sequence nh2-ser-phe-leu-leu-arg-cooh, mw= 634.76. coagulation factor ii (thrombin) receptor is a g protein-coupled receptor involved in the regulation of thrombotic response. proteolytic cleavage leads to the activation of the receptor(1). thrombin signalling in platelets contributes to hemostasis and thrombosis. endothelial pars participate in the regulation of vascular tone and permeability while in vascular smooth muscle they mediate contraction, proliferation, and hypertrophy. pars contribute to the pro-inflammatory response observed in atherosclerosis and restenosis. recent research has also implicated these novel receptors in muscle growth and bone cell differentiation and proliferation(2). in t cells, activation of par1, par2 and par3 induce tyrosine phosphorylation of vav1. activation of pars also led to an increase in tyrosine phosphorylation of zap-70 and slp-76, two key proteins in t cell receptor (tcr) signalling(3).figure1 formula of thrombin receptor activator for peptide 5 (trap-5)figure2 structure of thrombin receptor

References

1. Bahou WF, Nierman WC, Durkin AS, Potter CL, Demetrick DJ (September 1993). "Chromosomal assignment of the human thrombin receptor gene: localization to region q13 of chromosome 5". Blood 82 (5): 1532–7.2. Martorell L, Martínez-González J, Rodríguez C, Gentile M, Calvayrac O, Badimon L (February 2008). "Thrombin and protease-activated receptors (PARs) in atherothrombosis". Thromb. Haemost. 99 (2): 305–15.3. Bar-Shavit R, Maoz M, Yongjun Y, Groysman M, Dekel I, Katzav S (January 2002). "Signalling pathways induced by protease-activated receptors and integrins in T cells". Immunology 105 (1): 35–46.

H-SER-PHE-LEU-LEU-ARG-OH Preparation Products And Raw materials

Raw materials

Preparation Products

H-SER-PHE-LEU-LEU-ARG-OH Suppliers

Global( 92)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15928 58
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10248 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
Hangzhou Go Top Peptide Biotech
0571-88211921 sales1@gotopbio.com CHINA 2609 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
Alfa Chemistry
+1-5166625404 Info@alfa-chemistry.com United States 21317 58
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634 Cecilia@youngshechem.com China 2345 58

View Lastest Price from H-SER-PHE-LEU-LEU-ARG-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
H-SER-PHE-LEU-LEU-ARG-OH pictures 2022-10-11 H-SER-PHE-LEU-LEU-ARG-OH
141685-53-2
US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
 H-SER-PHE-LEU-LEU-ARG-OH pictures 2020-02-14 H-SER-PHE-LEU-LEU-ARG-OH
141685-53-2
US $7.00 / KG 1KG 99% 100kg Career Henan Chemical Co

H-SER-PHE-LEU-LEU-ARG-OH Spectrum

H-SER-PHE-LEU-LEU-ARG-OH SFLLR, Coagulation Factor II Receptor (1-5) (huMan), PAR-1 (1-5) (huMan), ThroMbin Receptor (1-5) (huMan), ThroMbin Receptor Activator Peptide 5, Proteinase Activated Receptor 1 (1-5) (huMan) SFLLR SER-PHE-LEU-LEU-ARG Thrombin Receptor Activator for Peptide 5 (TRAP-5) L-Arginine, L-seryl-L-phenylalanyl-L-leucyl-L-leucyl- L-Seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginine 141685-53-2 C30H50N8O7 Peptide Cardiovescular