PROPARACAINE
- CAS No.
- 298-50-0
- Chemical Name:
- PROPARACAINE
- Synonyms
- promecaine;PROPARACAINE;propantheline;Propanthelinium;PROPARACAINE USP/EP/BP;Proparacaine Propantheline;Diisopropylmethyl[2-(9H-xanthene-9-ylcarbonyloxy)ethyl]aminium;diisopropyl-methyl-[2-(9H-xanthene-9-carbonyloxy)ethyl]ammonium;[2-[(9H-Xanthen-9-ylcarbonyl)oxy]ethyl]diisopropylmethylaminium;methyl-di(propan-2-yl)-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium
- CBNumber:
- CB3181470
- Molecular Formula:
- C16H26N2O3
- Molecular Weight:
- 294.39
- MDL Number:
- MFCD05237244
- MOL File:
- 298-50-0.mol
- MSDS File:
- SDS
pka | pKa 3.22(H2O) (Uncertain) |
---|---|
FDA UNII | 1306V2B0Q8 |
ATC code | A03AB05 |
PROPARACAINE Chemical Properties,Uses,Production
Uses
Propantheline is used for treating stomach ulcers.
Uses
Anticholinergic.
Definition
ChEBI: Propantheline is a member of xanthenes.
brand name
Pro-Banthine (Searle).
Pharmacology
The pharmacological action of propantheline is qualitatively similar to atropine. It has a weaker effect on the CNS than atropine. Unlike atropine, it exhibits greater ganglioblocking action than antimuscarinic action. Moreover, upon overdose it causes neuromuscular curare-like blockage.
Synthesis
Propanetheline, N-methyl-N-(1-methylethyl)-N-[2-[(9H-xanthen-9- ylcarbonyl) oxy]ethyl]-2-propanaminium bromide (14.1.11), is synthesized by reacting xanthen-9-carboxylic acid chloride with 2-di-iso-propylaminoethanol, giving the ester (14.1.10), which upon reaction with methylbromide turns into the quaternary salt, propantheline (14.1.11) [12,13].
Veterinary Drugs and Treatments
Proparacaine is a rapid acting topical anesthetic useful for a variety of ophthalmic procedures including tonometry (intraocular pressure measurement), relief of corneal pain to facilitate examination, biopsy/sample collection, and to distinguish between corneal and uveal pain. Proparacaine primarily anesthetizes the cornea; with limited penetration into conjunctiva. Anesthesia is of short duration (5 – 10 minutes).
PROPARACAINE Preparation Products And Raw materials
Raw materials
Preparation Products
PROPARACAINE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5873 | 58 |
Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 | admin@firsky-cn.com | China | 436 | 58 |
Hebei Zhanyao Biotechnology Co. Ltd | 15369953316 +8615369953316 | admin@zhanyaobio.com | China | 2136 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 23899 | 58 |
AFINE CHEMICALS LIMITED | +86-008657185134551 +86-18958018566 | sales@afinechem.com | China | 15394 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52861 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
PT CHEM GROUP LIMITED | peter68@ptchemgroup.com | China | 35426 | 58 | |
Hu Bei Jiutian Bio-medical Technology CO.,Ltd | 027-88013699 17354350817 | Ryan@jiutian-bio.com | China | 7185 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50003 | 58 |
View Lastest Price from PROPARACAINE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-08-15 | Propantheline
298-50-0
|
US $50.00 / kg | 1kg | 0.99 | 20 tons | Hebei Yanxi Chemical Co., Ltd. | ||
2023-10-08 | Proparacaine
298-50-0
|
US $30.00 / KG | 1KG | 99% | 20T | Firsky International Trade (Wuhan) Co., Ltd | ||
2021-11-04 | Propantheline
298-50-0
|
US $10.00 / Kg/Bag | 1Kg/Bag | 99% | 20 Tons | Hebei Zhanyao Biotechnology Co. Ltd |
- Propantheline
298-50-0
- US $50.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
- Proparacaine
298-50-0
- US $30.00 / KG
- 99%
- Firsky International Trade (Wuhan) Co., Ltd
- Propantheline
298-50-0
- US $10.00 / Kg/Bag
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd