ChemicalBook >> CAS DataBase List >>9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID

9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID

CAS No.
212310-16-2
Chemical Name:
9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID
Synonyms
CAY10408;HJVBXPOYFHMZAS-QTUFFCAPSA-N;9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID;5-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,4R)-4-hydroxy-4-(1-propylcyclobutyl)-1-buten-1-yl]-5-oxocyclopentyl]-, (5Z)-
CBNumber:
CB3219636
Molecular Formula:
C23H36O5
Molecular Weight:
392.53
MDL Number:
MFCD05865284
MOL File:
212310-16-2.mol
Last updated:2023-06-08 09:03:09

9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID Properties

solubility DMF: 15 mg/ml; DMSO: 25 mg/ml; Ethanol: 15 mg/ml; PBS (pH 7.2): 3 mg/ml

SAFETY

Risk and Safety Statements

9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 13747 CAY10408 ≥98% 212310-16-2 1mg $150 2024-03-01 Buy
Cayman Chemical 13747 CAY10408 ≥98% 212310-16-2 5mg $668 2024-03-01 Buy
Cayman Chemical 13747 CAY10408 ≥98% 212310-16-2 10mg $1185 2024-03-01 Buy
AK Scientific 1582AH 9-oxo-11alpha,16R-Dihydroxy-17-cyclobutyl-5Z,13E-dien-1-oicacid 212310-16-2 5mg $841 2021-12-16 Buy
Product number Packaging Price Buy
13747 1mg $150 Buy
13747 5mg $668 Buy
13747 10mg $1185 Buy
1582AH 5mg $841 Buy

9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID Chemical Properties,Uses,Production

Description

Butaprost is a structural analog of prostaglandin E2 (PGE2) with good selectivity for the EP2 receptor subtype. Butaprost binds with about 1/10 the affinity of PGE2 to the recombinant murine EP2 receptor, and does not bind appreciably to any of the other murine EP receptors or DP, TP, FP, or IP receptors.1 CAY10408 is a free acid, 2-series analog of butaprost. It is the less active C-16 epimer compared to the 16(S) isomer, which has the same stereochemistry as butaprost. Butaprost has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells.2 Since the majority of reports related to butaprost utilize the methyl ester derivative,3,4 it may be some time before the precise pharmacology of the free acid compounds, like CAY10408, is reported.

References

1. Kiriyama, M., Ushikubi, F., Kobayashi, T., et al. Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells Br. J. Pharmacol. 122(2),217-224(1997).
2. Lawrence, R.A., and Jones, R.L. Investigation of the prostaglandin E (EP-) receptor subtype mediating relaxation of the rabbit jugular vein Br. J. Pharmacol. 105,817-824(1992).
3. Regan, J.W., Bailey, T.J., Pepperl, D.J., et al. Cloning of a novel human prostaglandin receptor with characteristics of the pharmacologically defined EP2 subtype Mol. Pharmacol. 46(2),213-220(1994).
4. Talpain, E., Armstrong, R.A., Coleman, R.A., et al. Characterization of the PGE receptor subtype mediating inhibition of superoxide production in human neutrophils Br. J. Pharmacol. 114(7),1459-1465(1995).

9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID Suppliers

Global( 19)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1991 58
Jinan ponder chemical co. LTD 0531-0000 thinklifescience@163.com China 19690 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58

212310-16-2(9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID)Related Search:

9-OXO-11ALPHA,16R-DIHYDROXY-17-CYCLOBUTYL-5Z,13E-DIEN-1-OIC ACID CAY10408 HJVBXPOYFHMZAS-QTUFFCAPSA-N 5-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,4R)-4-hydroxy-4-(1-propylcyclobutyl)-1-buten-1-yl]-5-oxocyclopentyl]-, (5Z)- 212310-16-2