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Sugammadex sodium

Sugammadex sodium
Sugammadex sodium structure
CAS No.
343306-79-6
Chemical Name:
Sugammadex sodium
Synonyms
ORG;CS-2749;Sugammadex Na;Sugammadex IMP;Glucose-sodium;Sugammadex sodico;Sugammdaex sodium;Sugammadex Sudium;Sugammadex soidum;6 Sugammadex Sodium
CBNumber:
CB32502868
Molecular Formula:
C72H104Na8O48S8
Formula Weight:
2177.97
MOL File:
343306-79-6.mol

Sugammadex sodium Properties

storage temp. 
Inert atmosphere,Room Temperature
CAS DataBase Reference
343306-79-6

Sugammadex sodium price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 24096 Sugammadex (sodium salt) ≥98% 343306-79-6 1mg $25 2021-12-16 Buy
Cayman Chemical 24096 Sugammadex (sodium salt) ≥98% 343306-79-6 5mg $113 2021-12-16 Buy
TRC S698100 SugammadexSodium 343306-79-6 100mg $250 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000360 SUGAMMADEX SODIUM 95.00% 343306-79-6 1G $5004.34 2021-12-16 Buy
DC Chemicals DC32003 Org25969sodium 343306-79-6 250 mg $200 2021-12-16 Buy

Sugammadex sodium Chemical Properties,Uses,Production

Description

To facilitate tracheal intubation, mechanical ventilation, and surgical access, NMB agents are frequently used as non-anesthetic adjuncts in surgical procedures. Sugammadex is able to function as a pharmacologic sink of rocuronium and vecuronium, another non-depolarizing neuromuscular blocker, without the cardiovascular adverse effects experienced with reversal agents that directly interact with the cholinergic system. The γ-cyclodextrin has been designed to enhance binding of the guest by incorporating acidic side chains to promote an electrostatic interaction with the positive nitrogen of the blocker. Starting with γ-cyclodextrin, these side chains are readily installed by first halogenating with iodine or bromine to provide a handle for nucleophilic displacement with either 3-mercaptopropionic acid in the presence of sodium hydride or with 3-mercaptopropionic acid methyl ester and cesium carbonate. The latter requires hydrolysis with sodium hydroxide to generate sugammadex sodium.

Chemical Properties

Colorless, orthorhombic crystals from DMF + water. d 1.446. Solubility in water.

Originator

Organon (Netherlands)

Uses

Sugammadex Sodium is the first in a class of drugs called selective relaxant binding agents that offers improved termination of the paralytic effects of neuromuscular blocking agents and may have many potential peri-operative benefits.

Uses

Reversal agent for neuromuscular blocking drugs.

Definition

ChEBI: An organic sodium salt that is the octasodium salt of sugammadex. Used for reversal of neuromuscular blockade induced by rocuronium and vecuronium in adults undergoing surgery.

brand name

Bridion

Side effects

The most common adverse effects included coughing, movement, vomiting, dry mouth, dysgeusia, hypotension, parosmia, and a sensation of changed temperature.Sugammadex is recommended for the reversal of neuromuscular blockade induced by rocuronium or vecuronium; it should not be used with other steroidal blocking agents since safety and efficacy data are not available for these situations. It should also not be partnered with non-steroidal neuromuscular blockers such as succinylcholine or benzylisoquinolinium-based drugs. Since sugammadex is predominantly cleared by the kidneys, care should be taken when administering this reversal agent in patients with renal impairment.

Sugammadex sodium Preparation Products And Raw materials

Raw materials

Preparation Products


Sugammadex sodium Suppliers

Global( 175)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Chengdu Aslee Biopharmaceuticals, Inc.
+86 28 85305008
may.yang@asleechem.com CHINA 964 58
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 9107 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
02783214688 bruce@xrdchem.cn CHINA 567 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 26782 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-0371-55982848
sales@coreychem.com China 29954 58
Jinan Chenghui-Shuangda Chemical Co.,Ltd
+86-531-58897082
+86-531-58897093 ericqiao@jnchsd.com CHINA 158 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
BOC Sciences
1-631-485-4226
1-631-614-7828 inquiry@bocsci.com United States 19752 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58

View Lastest Price from Sugammadex sodium manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-11-30 Sugammadex sodium
343306-79-6
US $16.00 / g 500g/Bag 99% 100KG Baoji Guokang Bio-Technology Co., Ltd.
2021-11-15 Sugammadex Sodium
343306-79-6
US $99.00 / KG 1KG 99% 5ton/Month Hebei Yirun Sega Biological Technology Co. Ltd
2021-11-09 Sugammadex sodium
343306-79-6
US $0.00 / KG 2KG 99% up, High Density 20 tons Sinoway Industrial co., ltd.

343306-79-6(Sugammadex sodium)Related Search:


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  • Sugammadex Sodium salt
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  • Sugammadex Sudium
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  • Sugammadex soidum
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  • Sugammadex sodium (Org-25969)
  • 343306-79-6
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  • C72H104Na8O48S8
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  • API
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