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Amifostine Thiol Dihydrochloride

CAS No.
14653-77-1
Chemical Name:
Amifostine Thiol Dihydrochloride
Synonyms
SKL052;WR-1065 2HCl;AMifostine Thiol;WR-1065 dihydrochloride;Amifostine Impurity 1 DiHCl;Amifostine Impurity 10 DiHCl;Amifostine Thiol Dihydrochloride;Amifostine thiol (hydrochloride);Amifostine Thiol Dihydrochloride (90%);Amifostine Impurity 2(Amifostine Thiol)
CBNumber:
CB32502994
Molecular Formula:
C5H14N2S
Molecular Weight:
134.24306
MDL Number:
MFCD00460339
MOL File:
14653-77-1.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59

Amifostine Thiol Dihydrochloride Properties

Melting point 184-186°C
storage temp. -20°C
solubility H2O: ≥20mg/mL
form powder
color white to off-white
Stability Hygroscopic
FDA UNII LE9VV16SZW

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H318
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-41
Safety Statements  26-39-41
WGK Germany  3
HS Code  2930909165
Toxicity mouse,LD50,intraperitoneal,400mg/kg (400mg/kg),European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 24, Pg. 48, 1989.
NFPA 704
0
3 0

Amifostine Thiol Dihydrochloride price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W2020 WR-1065 ≥98% (HPLC) 14653-77-1 10mg $100 2024-03-01 Buy
Sigma-Aldrich 1019428 Amifostine thiol United States Pharmacopeia (USP) Reference Standard 14653-77-1 50mg $1210 2024-03-01 Buy
Cayman Chemical 18612 Amifostine thiol (hydrochloride) 14653-77-1 5mg $45 2024-03-01 Buy
Cayman Chemical 18612 Amifostine thiol (hydrochloride) 14653-77-1 10mg $81 2024-03-01 Buy
Sigma-Aldrich W2020 WR-1065 ≥98% (HPLC) 14653-77-1 50mg $407 2024-03-01 Buy
Product number Packaging Price Buy
W2020 10mg $100 Buy
1019428 50mg $1210 Buy
18612 5mg $45 Buy
18612 10mg $81 Buy
W2020 50mg $407 Buy

Amifostine Thiol Dihydrochloride Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

A metabolite of Amifostine.

Biochem/physiol Actions

WR-1065 is cytoprotective cell-permeable reactive oxygen species scavenger and p53 activator and re-activator. Recently shown to have antiretroviral activity and an active metabolite of Amifostine which selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy.

storage

Desiccate at -20°C

Amifostine Thiol Dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Amifostine Thiol Dihydrochloride Suppliers

Global( 87)Suppliers
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Hubei Chuangliankangcheng Pharmaceutical Co., Ltd. 027-65388397 18164111589 3321478047@qq.com China 1995 55
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Amifostine Thiol Dihydrochloride 2-[(3-Aminopropyl)amino]ethanethioldihydrochloride Amifostine Thiol (50 mg) (2-[(3-aminopropyl)amino]ethanethiol, dihydrochloride) AMifostine Thiol 2-[(3-AMinopropyl)aMino]ethanethiol Hydrochloride WR-1065 dihydrochloride WR-1065 2HCl Amifostine Thiol Dihydrochloride (90%) 2-[(3-aminopropyl)amino]ethane-1-thiol dihydrochloride Amifostine Impurity 2(Amifostine Thiol) SKL052 Amifostine Thiol Dihydrochloride-d4Q: What is Amifostine Thiol Dihydrochloride-d4 Q: What is the CAS Number of Amifostine Thiol Dihydrochloride-d4 Amifostine Thiol-13C3 DihydrochlorideQ: What is Amifostine Thiol-13C3 Dihydrochloride Q: What is the CAS Number of Amifostine Thiol-13C3 Dihydrochloride Ethanethiol, 2-[(3-aminopropyl)amino]-, hydrochloride (1:2) Amifostine Thiol (2-[(3-aminopropyl)amino]ethanethiol, dihydrochloride) (1019428) WR1065,Amifostine thiol dihydrochloride,Inhibitor,MDM-2/p53,WR-1065,Amifostine thiol,inhibit Amifostine thiol (hydrochloride) Amifostine Impurity 1 DiHCl Amifostine Impurity 10 DiHCl Amifostine Thiol (50 mg) (Ethanethiol, 2-[(3-aminopropyl)amino]-, dihydrochloride) 14653-77-1 C5H16Cl2N2S C5H14N2S2HCl Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Sulfur & Selenium Compounds