Lansoprazole (sodiuM)
- CAS No.
- 226904-00-3
- Chemical Name:
- Lansoprazole (sodiuM)
- Synonyms
- AG-1749 sodium;Lansoprazole (sodiuM);Lansoprazole (sodiuM) USP/EP/BP;2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]benzimidazol-1-ide;sodium,2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]benzimidazol-1-ide
- CBNumber:
- CB32677070
- Molecular Formula:
- C16H13F3N3NaO2S
- Molecular Weight:
- 393.36
- MDL Number:
- MFCD28168552
- MOL File:
- 226904-00-3.mol
- MSDS File:
- SDS
storage temp. | Store at -20°C |
---|---|
solubility | insoluble in H2O; ≥15.05 mg/mL in EtOH; ≥58.9 mg/mL in DMSO |
form | solid |
FDA UNII | GV9NY1U369 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
Lansoprazole (sodiuM) price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
ChemScene | CS-1848 | Lansoprazolesodium | 226904-00-3 | 500mg | $50 | 2021-12-16 | Buy |
ApexBio Technology | B1290 | Lansoprazolesodium | 226904-00-3 | 10mM(in 1mL Ethanol) | $50 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0014457 | LANSOPRAZOLE SODIUM 95.00% | 226904-00-3 | 1G | $195.3 | 2021-12-16 | Buy |
Lansoprazole (sodiuM) Chemical Properties,Uses,Production
Biological Activity
lansoprazole sodium is a proton-pump inhibitor (ppi) and also can inhibit cytochrome p450 [1].lansoprazole sodium is a substituted benzimidazole and has been widely used as acid inhibitory agent for treatment of disorders related to gastric acid secretion. lansoprazole sodium has been exhibited to inhibit stomach acid by blocking the h+/k+atpase system at the secretory surface of gastric parietal cells. as the human p450 enzymes including cyp2c9,2c19, 2d6 and 3a4, in addition, lansoprazole sodium has been reported to have the competitively inhibitory effect on the activity of cyp2c9 in hlm with a ki value of 21μm. lansoprazole sodium has been found to be potent cyp2c19 inhibitor with a ki value of about 1μm in both hlm and rcyp2c19 tests. besides, lansoprazole sodium has been revealed to inhibit the activities if cyp2d6 and cyp3a4 with ic50 values of both>200μm [1].
References
[1] li xq1, andersson tb, ahlström m, weidolf l.comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome p450 activities. drug metab dispos. 2004 aug;32(8):821-7.
Lansoprazole (sodiuM) Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 27644 | 58 |
Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9329 | 58 |
Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4428 | 55 |
Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12308 | 58 |
Musechem | +1-800-259-7612 | info@musechem.com | United States | 4662 | 60 |
View Lastest Price from Lansoprazole (sodiuM) manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-07-13 | Lansoprazole sodium
226904-00-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | ||
2021-07-10 | Lansoprazole sodium
226904-00-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
- Lansoprazole sodium
226904-00-3
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
- Lansoprazole sodium
226904-00-3
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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