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2,5-Dichloro-p-xylene

2,5-Dichloro-p-xylene structure

CAS No.: 1124-05-6

Chemical Name:: 2,5-Dichloro-p-xylene

Synonyms: ,5-DICHLORO-P-XYLENE;1,4-Dichloro-p-xylene;2,5-Dichloro-p-xylene;p-xylene,2,5-dichloro-;p-Xylene, 2,5-dichloro-;2,5-Dichloro-para-xylene;2,5-two chloroparaxylene;2,5-Dichloro-p-xylene 97%;2,5-Dichloro-p-xylene >2,5-DICHLORO-P-XYLENE 98+%

CBNumber:: CB3281237

Molecular Formula:: C8H8Cl2

Molecular Weight:: 175.06

MDL Number:: MFCD00000610

MOL File:: 1124-05-6.mol

MSDS File:: SDS

Last updated:2026-09-12 18:51:58

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2,5-Dichloro-p-xylene Properties

Melting point	69-70 °C (lit.)
Boiling point	222 °C (lit.)
Density	1.2520 (estimate)
refractive index	1.5544 (estimate)
Flash point	221-223°C
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Sparingly), DMSO (Slightly, Heated), Hexanes (Slightly), Methanol
form	Solid
color	White to Pale Yellow
Henry's Law Constant	2.7×10^-3 mol/(m³Pa) at 25℃, Zhang et al. (2010)
InChI	1S/C8H8Cl2/c1-5-3-8(10)6(2)4-7(5)9/h3-4H,1-2H3
InChIKey	UTGSRNVBAFCOEU-UHFFFAOYSA-N
SMILES	Cc1cc(Cl)c(C)cc1Cl
CAS DataBase Reference	1124-05-6(CAS DataBase Reference)
FDA UNII	7P8M86ZOB2
NIST Chemistry Reference	Benzene, 1,4-dichloro-2,5-dimethyl-(1124-05-6)
EPA Substance Registry System	2,5-Dichloro-p-xylene (1124-05-6)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H335-H315-H319

Precautionary statements

P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a

PPE

Eyeshields, Gloves, type N95 (US)

Risk Statements

36/37/38

Safety Statements

26-37

WGK Germany

TSCA

TSCA listed

HS Code

2903.99.8001

Storage Class

11 - Combustible Solids

NFPA 704

	0
0		0

2,5-Dichloro-p-xylene price More Price(56)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	D76404	2,5-Dichloro-p-xylene 97%	1124-05-6	25g	$85.4	2023-01-07	Buy
Sigma-Aldrich	D76404	2,5-Dichloro-p-xylene 97%	1124-05-6	100g	$193	2023-01-07	Buy
TCI Chemical	D0431	2,5-Dichloro-p-xylene	1124-05-6	25G	$100	2026-04-30	Buy
TRC	TRC-D438885-5G	2,5-Dichloro-1,4-dimethylbenzene	1124-05-6	5g	$96	2026-06-03	Buy
TRC	TRC-D438885-1G	2,5-Dichloro-1,4-dimethylbenzene	1124-05-6	1g	$70	2026-06-03	Buy

Product number	Packaging	Price	Buy
D76404	25g	$85.4	Buy
D76404	100g	$193	Buy
D0431	25G	$100	Buy
TRC-D438885-5G	5g	$96	Buy
TRC-D438885-1G	1g	$70	Buy

2,5-Dichloro-p-xylene Chemical Properties, Uses, Production

Uses

2,5-Dichloro-1,4-dimethylbenzene can be used to produce phototropic photosensitive composition containing fluoran colorformer.

Synthesis

106-42-3

1124-05-6

The general procedure for the synthesis of 2,5-dichloro-p-xylene from p-xylene is as follows: In a 500 ml round-bottomed flask, 330 grams of p-xylene (3.1 moles), 0.50 grams (0.003 moles) of ferric chloride, and 0.58 grams (0.003 moles) of dibenzyl sulphide were added and mixed with stirring. The temperature of the mixture was raised to 30°C and 521 g of chlorine gas was slowly passed through the mixture at this temperature over a period of 8 hours. The temperature was gradually raised to about 60°C depending on the cure of the reaction mixture. Upon completion of the chlorination reaction, the crude product was analyzed by gas chromatography, which showed the following composition: degree of chlorination (number of moles of chlorine substituted for 1 mole of p-xylene) 2.21, 2,5-dichloro-p-xylene (2,5-DCPX) 74.5%, 2,3-dichloro-p-xylene (2,3-DCPX) 5.1%, trichloro-p-xylene 19.9%, tetrachloro-p-xylene 0.5%. Subsequently, the crude product was purged with nitrogen and distilled according to the same method as in Example 1 to obtain 255.6 g of crude 2,5-DCPX with a purity of 93.9%. 281.8 g of isopropanol was added thereto, heated to 60° C. to dissolve the crystals, and cooled to 19° C. to crystallize, to ultimately obtain 187 g (53.4% yield) of 2,5-DCPX with a 99.9% purity .

References

[1] Patent: JP2017/190306, 2017, A. Location in patent: Paragraph 0024
[2] Helvetica Chimica Acta, 1944, vol. 27, p. 274,290
[3] Patent: US2412389, 1943,
[4] Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1935, vol. 200, p. 936
[5] Annales de Chimie (Cachan, France), 1936, vol. <11> 5, p. 5,57

2,5-Dichloro-p-xylene Preparation Products And Raw materials

Raw materials

Ferric chloride Dichloromethane 2-Chloro-1,4-dimethylbenzene p-Xylene

Preparation Products

2,5-Dichloro-p-xylene Suppliers

Global Suppliers ( 231)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai TongYuan Chemical Co., Ltd.	021-021-69182866 13701855675	tongyuanchem@126.com	China	4184	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
INTATRADE GmbH	+49 3493/605464	sales@intatrade.de	Germany	3563	66
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
future industrial shanghai co., ltd	400-0066400 13621662912	sales@jonln.com	China	1989	65
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Jia Xing Isenchem Co.,Ltd	0573-85285100 18627885956	isenchem@163.com	China	9389	66
Shanghai Longsheng chemical Co.,Ltd.	58099637 13585536065	sales@shlschem.com	China	9880	59

Supplier	Advantage
Shanghai TongYuan Chemical Co., Ltd.	58
J & K SCIENTIFIC LTD.	76
INTATRADE GmbH	66
3B Pharmachem (Wuhan) International Co.,Ltd.	69
future industrial shanghai co., ltd	65
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Jia Xing Isenchem Co.,Ltd	66
Shanghai Longsheng chemical Co.,Ltd.	59

View Latest Price from 2,5-Dichloro-p-xylene manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-02	2,5-DICHLORO-P-XYLENE 1124-05-6	$1.00-100.00	1KG	99%		Henan Fengda Chemical Co., Ltd
2026-05-28	2,5-DICHLORO-P-XYLENE 1124-05-6	$2.00-5.00	1KG	99%	10000kg	Hebei Chuanghai Biotechnology Co,.LTD
2026-03-20	2,5-DICHLORO-P-XYLENE 1124-05-6		1KG	99%	20 mt	Hebei Chuanghai Biotechnology Co., Ltd

2,5-DICHLORO-P-XYLENE
1124-05-6
$1.00-100.00
99%
Henan Fengda Chemical Co., Ltd

2,5-DICHLORO-P-XYLENE
1124-05-6
$2.00-5.00
99%
Hebei Chuanghai Biotechnology Co,.LTD

2,5-DICHLORO-P-XYLENE
1124-05-6
99%
Hebei Chuanghai Biotechnology Co., Ltd

2,5-Dichloro-p-xylene Spectrum

2,5-DICHLORO-P-XYLENE(1124-05-6)MS 2,5-DICHLORO-P-XYLENE(1124-05-6)¹HNMR 2,5-DICHLORO-P-XYLENE(1124-05-6)¹³CNMR 2,5-DICHLORO-P-XYLENE(1124-05-6)IR1 2,5-DICHLORO-P-XYLENE(1124-05-6)IR2 2,5-DICHLORO-P-XYLENE(1124-05-6)IR3 2,5-DICHLORO-P-XYLENE(1124-05-6)Raman

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2,5-two chloroparaxylene 2,5-Dichloro-p-xylene 97% 1,4-DICHLORO-2,5-DIMETHYLBENZENE benzene,1,4-dichloro-2,5-dimethyl- p-Xylene, 2,5-dichloro- p-xylene,2,5-dichloro- 2,5-DICHLORO-P-XYLENE 98+% 1,4-dichloro-2,5-dimethyl-benzen 2,5-Dichloro-1,4-dimethylbenzene 2,5-Dichloro-para-xylene 2,5-Dichloro-p-xylene,pract. 2,5-Dichloro-p-xylene ,97% 1,4-Dichloro-p-xylene 2,5-Dichloro-p-xylene > 2,5-DICHLORO-P-XYLENE ISO 9001：2015 REACH ,5-DICHLORO-P-XYLENE 1,4-Dichloro-p-xylene in isooctane 2,5-Dichloro-p-xylene 2,5-Dichloro4-Methyl-toluene 2,5-Dichloro-p-xylene 1124-05-6 CH32C6H2Cl2 Organic Building Blocks Halogenated Hydrocarbons Building Blocks Aryl C8 Building Blocks Halides Phenyls & Phenyl-Het Phenyls & Phenyl-Het Aryl C8 Halogenated Hydrocarbons Chemical Synthesis Halogenated Hydrocarbons Organic Building Blocks