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ChemicalBook >> CAS DataBase List >>2'-Azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine

2'-Azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine

2'-Azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine Structure
2'-Azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine structure
CAS No.
177980-10-8
Chemical Name:
2'-Azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine
Synonyms
2'-Azido-2'-deoxy-5'-O-DMT-uridine;2’-Azido-2’-deoxy-5’-O-DMTr-uridine;2'-azido-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine;2’-Azido-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)uridine;2'-Azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine
CBNumber:
CB33051679
Molecular Formula:
C30H29N5O7
Molecular Weight:
571.59
MDL Number:
MOL File:
177980-10-8.mol
Last updated:2026-05-11 19:39:08
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2'-Azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine Chemical Properties, Uses, Production

Uses

2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

2'-Azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine synthesis

40615-36-9
26929-65-7
177980-10-8
Synthesis of 2'-Azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine from 4,4'-Dimethoxytrityl chloride and 2'-Azido-2'-deoxyuridine

2'-Azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine Preparation Products And Raw materials

Raw materials

Preparation Products

2'-Azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine Suppliers

Global Suppliers ( 18)
Supplier Tel Email Country ProdList Advantage
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58
Zhengzhou GranLen pharmaceutical Technology Co., Ltd. 0371-85513397 info@granlen.com China 497 55
Zhengzhou Granlen Sciences, ltd. 0371-85513397 +86-18610099868 info@granlen.com China 1890 58
NewCan Biotech Limited +86-571-86912261 19975279805 sales@newcanbio.com China 9984 58
NINGBOBENKANGJS PHARMTECHCO., LTD +8615990591583 15990591583 CHINA 2028 58
BOC Sciences 16314854226 inquiry@bocsci.com United States 9713 58
Ningbo Benkang jishi Pharmaceutical Technology Co., Ltd. 15990591583 China 6129 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 contact@trustwe.com China 5771 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Xi'an Kezhan Biotechnology Co., Ltd. 18729005399 78282739@qq.com China 2300 58
Supplier Advantage
T&W GROUP 58
Zhengzhou GranLen pharmaceutical Technology Co., Ltd. 55
Zhengzhou Granlen Sciences, ltd. 58
NewCan Biotech Limited 58
NINGBOBENKANGJS PHARMTECHCO., LTD 58
BOC Sciences 58
Ningbo Benkang jishi Pharmaceutical Technology Co., Ltd. 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 58
TargetMol Chemicals Inc. 58
Xi'an Kezhan Biotechnology Co., Ltd. 58

View Latest Price from 2'-Azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine manufacturers

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2'-Azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine pictures 2026-05-11 2'-Azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine
177980-10-8
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177980-10-8 (2'-Azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine) Related Search:

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2'-Azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine 2'-Azido-2'-deoxy-5'-O-DMT-uridine 2’-Azido-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)uridine 2'-azido-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine 2’-Azido-2’-deoxy-5’-O-DMTr-uridine 177980-10-8