T-3364366
- CAS No.
- 1356354-09-0
- Chemical Name:
- T-3364366
- Synonyms
- T-3364366;T-3364366, 10 mM in DMSO;N-[2-({4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]-3H,4H-thieno[3,4-d]pyrimidin-2-yl}sulfanyl)ethyl]acetamide;N-[2-[[3,4-Dihydro-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]thieno[3,4-d]pyrimidin-2-yl]thio]ethyl]acetamide;Acetamide, N-[2-[[3,4-dihydro-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]thieno[3,4-d]pyrimidin-2-yl]thio]ethyl]-
- CBNumber:
- CB33344775
- Molecular Formula:
- C18H16F3N3O3S2
- Molecular Weight:
- 443.46
- MDL Number:
- MFCD31726175
- MOL File:
- 1356354-09-0.mol
| Product description | Number | Pack Size | Price |
| T3364366 ≥98%(HPLC) | 6106 | 10 | $168 |
| T3364366 ≥98%(HPLC) | 6106 | 50 | $704 |
| T 3364366 NEW | BT167269 | 10mg | $105 |
| N-[2-[4-Oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]thieno[3,4-d]pyrimidin-2-yl]sulfanylethyl]acetamide | 6511EA | 10mg | $191 |
| T 3364366 NEW | BT167269 | 50mg | $367.5 |
T-3364366 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 6106 | T3364366 ≥98%(HPLC) | 1356354-09-0 | 10 | $168 | 2021-12-16 | Buy |
| Tocris | 6106 | T3364366 ≥98%(HPLC) | 1356354-09-0 | 50 | $704 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BT167269 | T 3364366 NEW | 1356354-09-0 | 10mg | $105 | 2021-12-16 | Buy |
| AK Scientific | 6511EA | N-[2-[4-Oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]thieno[3,4-d]pyrimidin-2-yl]sulfanylethyl]acetamide | 1356354-09-0 | 10mg | $191 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BT167269 | T 3364366 NEW | 1356354-09-0 | 50mg | $367.5 | 2021-12-16 | Buy |
T-3364366 Chemical Properties,Uses,Production
Uses
T-3364366 is a reversible, slow-binding, thienopyrimidinone delta-5 desaturase (D5D) inhibitor with IC50s of 1.9 nM and 2.1 nM in HepG2 and RLN-10 cells, respectively. T-3364366 exhibits potent D5D (IC500=19 nM) inhibitory activity and excellent selectivity away from delta-6 desaturase (D6D, IC50=6200 nM) and delta-9 desaturase (stearoyl-CoA desaturase, SCD,50 >10000 nM) in the enzymatic activity assay[1].
storage
Store at +4°C
References
[1] Ikuo Miyahisa, et al. T-3364366 Targets the Desaturase Domain of Delta-5 Desaturase with Nanomolar Potency and a Multihour Residence Time. ACS Med Chem Lett. 2016 Aug 10;7(9):868-72. DOI:10.1021/acsmedchemlett.6b00241
T-3364366 Preparation Products And Raw materials
Raw materials
Preparation Products
T-3364366 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39035 | 58 |
| Aceschem Inc. | +1-817863-6948 +1-（817）863-6948 | sales@aceschem.com | United States | 19632 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Nanjing Dulai Biotechnology Co., Ltd. | 025-846993838003-8003 18013301590 | njduly@126.com | China | 3249 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
| ShangHai ChuanQian Chemcial Technique Centre | 15869524721 | 3525679403@qq.com | China | 4989 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24961 | 58 |
