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DL-O-METHYLSERINE

CAS No.
19794-53-7
Chemical Name:
DL-O-METHYLSERINE
Synonyms
Methylserine;DL-Ser(Me)-OH;DL-H-Ser(Me)-OH;O-Methyl-DL-serin;DL-O-METHYLSERINE;O-METHYL-DL-SERINE;DL-O-Methylserine>DL-O-Methylserine,>98%,;2-Amino-3-methoxy-propionic acid;DL-O-Methylserine
CBNumber:
CB3393228
Molecular Formula:
C4H9NO3
Molecular Weight:
119.12
MDL Number:
MFCD00037773
MOL File:
19794-53-7.mol
MSDS File:
SDS
Last updated:2025-08-08 17:45:00
Product description Number Pack Size Price
O-Methyl-DL-serine M7378 1g $452
DL-O-Methylserine >98.0%(T) M0888 1g $161
DL-O-Methylserine >98.0%(T) M0888 5g $541
O-Methylserine M327520 5g $435
2-AMINO-3-METHOXYPROPANOIC ACID 95.00% CHM0001536 1G $708.48
More product size

DL-O-METHYLSERINE Properties

Boiling point 260.6±30.0 °C(Predicted)
Density 1.195±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form powder to crystal
pka 2.10±0.10(Predicted)
color White to Almost white
CAS DataBase Reference 19794-53-7(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII R5MJK98YKK

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
WGK Germany  3
HazardClass  IRRITANT
HS Code  2922500090

DL-O-METHYLSERINE price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M7378 O-Methyl-DL-serine 19794-53-7 1g $452 2023-06-20 Buy
TCI Chemical M0888 DL-O-Methylserine >98.0%(T) 19794-53-7 1g $161 2025-07-31 Buy
TCI Chemical M0888 DL-O-Methylserine >98.0%(T) 19794-53-7 5g $541 2025-07-31 Buy
TRC M327520 O-Methylserine 19794-53-7 5g $435 2021-12-16 Buy
American Custom Chemicals Corporation CHM0001536 2-AMINO-3-METHOXYPROPANOIC ACID 95.00% 19794-53-7 1G $708.48 2021-12-16 Buy
Product number Packaging Price Buy
M7378 1g $452 Buy
M0888 1g $161 Buy
M0888 5g $541 Buy
M327520 5g $435 Buy
CHM0001536 1G $708.48 Buy

DL-O-METHYLSERINE Chemical Properties,Uses,Production

Uses

O-Methylserine acts as a reagent for the synthesis of D-serine transporter inhibitors which are used pharmaceutically for the treatment of visual system disorders and enhancement of the visual functions.

Definition

ChEBI: O-Methyl-DL-serine is an alpha-amino acid.

Synthesis

METHYL 2-BROMO-3-METHOXYPROPIONATE

27704-96-7

DL-O-METHYLSERINE

19794-53-7

1) Add 215 g of methyl acrylate to the reaction flask. The temperature of the reaction system was raised to 55°C and 500 g of bromine was added slowly and dropwise. The reaction was maintained for 1 hour. Subsequently, concentration was carried out under reduced pressure at 60 °C to remove the excess bromine. To the residue was added 1260 g of methanol and the mixture was cooled to -17 °C. At this temperature, 127 g of sodium methanol was added and the reaction was carried out for 5.5 hours. Upon completion of the reaction, the methanol was removed by distillation under reduced pressure. 750 g of ammonia was added to the reaction mixture and the reaction was held at 20-25°C for 3 hours. Finally, 260 g of O-methyl-DL-serine was obtained by concentrated crystallization.

References

[1] Patent: CN105949074, 2016, A. Location in patent: Paragraph 0041

DL-O-METHYLSERINE Preparation Products And Raw materials

Global( 140)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
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Alchem Pharmtech,Inc.
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CONIER CHEM AND PHARMA LIMITED
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View Lastest Price from DL-O-METHYLSERINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
DL-O-METHYLSERINE pictures 2019-12-20 DL-O-METHYLSERINE
19794-53-7
US $1.00 / KG 1KG 99% 100kg Career Henan Chemical Co

DL-O-METHYLSERINE Spectrum

O-Methyl-DL-serin 2-Amino-3-methoxy-propionic acid DL-H-Ser(Me)-OH Methylserine O-METHYL-DL-SERINE DL-O-METHYLSERINE DL-O-Methylserine DL-O-Methylserine> DL-O-Methylserine,>98%, DL-Ser(Me)-OH 19794-53-7 I - Z Modified Amino Acids Biochemicals and Reagents BioChemical Amino Acids and Peptides Amino Acids I - Z Modified Amino Acids