FOLIC ACID DIHYDRATE
- CAS No.
- 75708-92-8
- Chemical Name:
- FOLIC ACID DIHYDRATE
- Synonyms
- FolicAcidB.P.;PGA DIHYDRATE;FOLIC ACID pure;FOLIC ACID DIHYDRATE;PTEROYLGLUTAMIC ACID;FOLIC ACID, 500MG, NEAT;VitaMin M or VitaMin Bc;FOLIC ACID DIHYDRATE 97%;PGA, Pteroylglutamic acid;PTEROYLGLUTAMIC ACID DIHYDRATE
- CBNumber:
- CB3453412
- Molecular Formula:
- C19H23N7O8
- Molecular Weight:
- 477.43
- MDL Number:
- MFCD00150769
- MOL File:
- 75708-92-8.mol
| Melting point | 250°C |
|---|---|
| storage temp. | Store at RT. |
| solubility | Aqueous Acid (Slightly), Aqueous Base (Slightly), DMSO (Slightly) |
| pka | pK1:8.26 (25°C) |
| form | Solid |
| color | Yellow to Dark Yellow |
| Water Solubility | Miscible with water. |
| Merck | 14,4221 |
| BRN | 100781 |
| CAS DataBase Reference | 75708-92-8 |
| FDA UNII | 0S1T5C0JZL |
FOLIC ACID DIHYDRATE price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | A14300 | Folic acid dihydrate, 97% | 75708-92-8 | 25g | $67.65 | 2024-03-01 | Buy |
| Alfa Aesar | A14300 | Folic acid dihydrate, 97% | 75708-92-8 | 100g | $231 | 2024-03-01 | Buy |
| TRC | F680328 | FolicAcidDihydrate | 75708-92-8 | 2.5g | $75 | 2021-12-16 | Buy |
| Chem-Impex | 01422 | Folicaciddihydrate,97.0-102.0%(Assay),meetsUSPspecifications 97.0-102.0%(Assay) | 75708-92-8 | 250G | $104.83 | 2021-12-16 | Buy |
| Chem-Impex | 01422 | Folic acid dihydrate 97.0-102.0% (Assay) | 75708-92-8 | 1KG | $260 | 2021-12-16 | Buy |
FOLIC ACID DIHYDRATE Chemical Properties,Uses,Production
Chemical Properties
Yellow to yellow-orange crystalline powd
Uses
Vitamin B9. A B-complex vitamin necessary for the body to produce red blood cellsFolic acid dehydrate is used to form non-covalent complexes with polyethylenimine. It is used for the delivery of genes, which finds application in gene therapy. It is a B-complex vitamin, which is necessary for the body to produce red blood cells.
Purification Methods
If paper chromatography indicates impurities, then recrystallise it from hot H2O or from dilute acid [Walker et al. J Am Chem Soc 70 19 1948]. Impurities may be removed by repeated extraction with n-BuOH of a neutral aqueous solution of folic acid (by suspending in H2O and adding N NaOH dropwise till the solid dissolves, then adjusting the pH to ~7.0-7.5) followed by precipitation with acid, filtration, or better collected by centrifugation and recrystallised form hot H2O. [Blakley Biochem J 65 331 1975, Kalifa et al. Helv Chim Acta 6 1 2739 1978.] Chromatography on cellulose followed by filtration through charcoal has also been used to obtain pure acid. [Sakami & Knowles Science 129 274 1959.] UV: max 247 and 296nm ( 12,800 and 18,700) in H2O pH 1.0; 282 and 346nm ( 27.600 and 7,200) in H2O pH 7.0; 256, 284 and 366nm ( 24600, 24,500 and 86,00) in H2O pH 13 [Rabinowitz in The Enzymes (Boyer et al. Eds), 2 185 1960]. [Beilstein 26 III/IV 3944.]
FOLIC ACID DIHYDRATE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Alfa Chemistry | info@alfa-chemistry.com | United States | 2344 | 58 | |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30132 | 84 |
| Energy Chemical | 021-021-58432009 400-005-6266 | sales8178@energy-chemical.com | China | 44700 | 61 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14443 | 57 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9823 | 79 |
| Suzhou yacoo science co.,Ltd | 0512-87182056 18013166090 | lingling.qi@yacoo.com.cn | China | 7300 | 60 |