NSC73306

NSC73306 structure

CAS No.: 79560-74-0

Chemical Name:: NSC73306

Synonyms: NSC73306;NSC73306 >=98% (HPLC);(3Z)-1H-Indole-2,3-dione 3-[N-(4-Methoxyphenyl )thiosemicarbazone;Hydrazinecarbothioamide, 2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)-N-(4-methoxyphenyl)-

CBNumber:: CB34739682

Molecular Formula:: C16H14N4O2S

Molecular Weight:: 326.37

MDL Number:

MOL File:: 79560-74-0.mol

MSDS File:: SDS

Last updated:2023-04-23 13:52:06

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NSC73306 Properties

Melting point	240 °C(Solv: ethanol (64-17-5))
Density	1.38±0.1 g/cm3(Predicted)
storage temp.	2-8°C
pka	7.40±0.20(Predicted)
form	powder
color	yellow to light brown

NSC73306 price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML1897	NSC73306 ≥98% (HPLC)	79560-74-0	5mg	$105	2024-03-01	Buy
Sigma-Aldrich	SML1897	NSC73306 ≥98% (HPLC)	79560-74-0	25mg	$376	2022-05-15	Buy

Product number	Packaging	Price	Buy
SML1897	5mg	$105	Buy
SML1897	25mg	$376	Buy

NSC73306 Chemical Properties,Uses,Production

Uses

(3Z)-1H-Indole-2,3-dione 3-[N-(4-Methoxyphenyl )thiosemicarbazone is a compound involved in the design and synthesis of novel anticancer agents that have the potential to overcome multidrug resistance.

Biochem/physiol Actions

NSC73306, a thiosemicarbazone, is a cell penetrant, cytotoxic agent that exhibits greater toxicity against cells expressing functional P-gp (P-glycoprotein) than against other cells. Irrespective of variations in cell line background, NSC73306 consistently demonstrated a Pgp-potentiated MDR-selective toxicity. It appears that NSC73306 is transported into the cell by copper transporter 1 (CTR1, SLC31A1). It is not P-gp inhibitor.

NSC73306 Preparation Products And Raw materials

Raw materials

Preparation Products

NSC73306 Suppliers

Global( 4)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44941	58

Supplier	Advantage
Sigma-Aldrich	80
Energy Chemical	58

NSC73306 NSC73306 >=98% (HPLC) (3Z)-1H-Indole-2,3-dione 3-[N-(4-Methoxyphenyl )thiosemicarbazone Hydrazinecarbothioamide, 2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)-N-(4-methoxyphenyl)- 79560-74-0