CHRYSOMYCIN B
- CAS No.
- 83852-56-6
- Chemical Name:
- CHRYSOMYCIN B
- Synonyms
- B,ChrysoMycin;CHRYSOMYCIN B USP/EP/BP;ChrysoMycin M, VirenoMycin M, Albacarcin M;6H-Benzo[d]naphtho[1,2-b]pyran-6-one, 4-(6-deoxy-3-C-methyl-β-gulopyranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl-;4-(6-Deoxy-3-C-methyl-beta-gulopyranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl-6H-benzo[d]naphtho[1,2-b]pyran-6-one;6H-Benzo[d]naphtho[1,2-b]pyran-6-one,4-(6-deoxy-3-C-methyl-b-gulopyranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl- (9CI)
- CBNumber:
- CB3503294
- Molecular Formula:
- C27H28O9
- Molecular Weight:
- 496.51
- MDL Number:
- MFCD07370132
- MOL File:
- 83852-56-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312-H319-H351 | |||||||||
| Precautionary statements | P201-P202-P264-P270-P280-P301+P312-P330-P302+P352-P305+P351+P338-P308+P313-P321-P362+P364-P337+P313-P405-P501 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
CHRYSOMYCIN B price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C6491 | Chrysomycin B ≥98%(HPLC),solid | 83852-56-6 | 100μg | $305 | 2022-05-15 | Buy |
| Cayman Chemical | 14189 | Chrysomycin B ≥98% | 83852-56-6 | 250μg | $166 | 2024-03-01 | Buy |
| Cayman Chemical | 14189 | Chrysomycin B ≥98% | 83852-56-6 | 1mg | $395 | 2024-03-01 | Buy |
| TRC | C433035 | Chrysomycin B | 83852-56-6 | 500μg | $185 | 2021-12-16 | Buy |
| TRC | C433035 | Chrysomycin B | 83852-56-6 | 250μg | $115 | 2021-12-16 | Buy |
CHRYSOMYCIN B Chemical Properties,Uses,Production
Description
Chrysomycin B is an antibiotic isolated from a strain of Streptomyces. It differs from its analog chrysomycin A by having a methyl, rather than vinyl, group in the 8-position of the chromophore. Like its analog, chrysomycin B suppresses the growth of transplantable tumors in mice, an effect that may be related to its ability to bind DNA. It also causes DNA damage in the human lung adenocarcinoma A549 cell line and inhibits topoisomerase II. Chrysomycin B is structurally very similar to gilvocarcin V, which promotes DNA cross-linking with histone 3 and GRP78 when photoactivated by near-UV light.
Uses
Chrysomycin B is a minor analogue in a complex of C-glycoside antitumor actives isolated from Streptomyces. Chrysomycin B, containing a methyl group in the 8-position, is less active than its vinyl analogue (Chrysomycin A), albeit still a potent antitumor active and an inhibitor of the catalytic activity of human topoisomerase II. More recent research on related metabolites, the gilvocarcins, suggests that chrysomycins may act as photoactivated cross-linkers of DNA to histones.
Uses
Chrysomycin B is a minor analogue in a complex of C-glycoside antitumour actives isolated from Streptomyces. Chrysomycin B, containing a methyl group in the 8-position, is less active than its vinyl analogue (Chrysomycin A), albeit still a potent antitumour active and an inhibitor of the catalytic activity of human topoisomerase II. More recent research on related metabolites, the gilvocarcins, suggests that chrysomycins may act as photoactivated crosslinkers of DNA to histones.
Uses
Chrysomycin B is an inhibitor of the catalytic activity of human topoisomerase II.
storage
+4°C
CHRYSOMYCIN B Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 18192627656 | 1012@dideu.com | China | 3320 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29067 | 58 |
| BOC Sciences | +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4428 | 55 |
| Alta Scientific Co., Ltd. | 022-6537-8550 15522853686 | sales@altasci.com.cn | China | 4515 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shanghai Xilong Biochemical Technology Co., Ltd. | 021-52907766-8042 | China | 9947 | 58 | |
| Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4587 | 58 |
| Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4381 | 58 |
View Lastest Price from CHRYSOMYCIN B manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-20 | CHRYSOMYCIN B USP/EP/BP
83852-56-6
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2020-05-13 | Chrysomycin B
83852-56-6
|
US $0.01-1.00 / KG | 1KG | 99% | 50 tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-03-12 | CHRYSOMYCIN B
83852-56-6
|
US $1.00 / KG | 1KG | 99.0% | 100kg | Career Henan Chemical Co |
-
- CHRYSOMYCIN B USP/EP/BP
83852-56-6
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- Chrysomycin B
83852-56-6
- US $0.01-1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- CHRYSOMYCIN B
83852-56-6
- US $1.00 / KG
- 99.0%
- Career Henan Chemical Co