ChemicalBook >> CAS DataBase List >>Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate

CAS No.
887267-53-0
Chemical Name:
Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate
Synonyms
Ethyl 3-(2,5-difluorophenyl);ETHYL 2,5-DIFLUOROBENZOYLACETATE;Ethyl 2,5-difluoro-β-oxobenzenepropanoate;ETHYL 3-(2,5-DIFLUOROPHENYL)-3-OXOPROPANOATE;Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate 95+%;Benzenepropanoic acid, 2,5-difluoro-β-oxo-, ethyl ester;3-(2,5-Difluoro-phenyl)-3-oxo-propionic acid ethyl ester;2-fluoro-3-(3-fluorophenyl)-3-oxopropanoic acid ethyl ester
CBNumber:
CB3689431
Molecular Formula:
C11H10F2O3
Molecular Weight:
228.19
MDL Number:
MFCD07783808
MOL File:
887267-53-0.mol
MSDS File:
SDS
Last updated:2023-10-20 10:42:06

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Properties

Boiling point 275.7±25.0 °C(Predicted)
Density 1.251±0.06 g/cm3(Predicted)
pka 10.28±0.50(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
HS Code  2916399090

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC E916705 Ethyl3-(2,5-Difluorophenyl)-3-oxopropanoate 887267-53-0 500mg $285 2021-12-16 Buy
SynQuest Laboratories 2629-3-30 Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate 97% 887267-53-0 250mg $291 2021-12-16 Buy
SynQuest Laboratories 2629-3-30 Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate 97% 887267-53-0 1g $795 2021-12-16 Buy
American Custom Chemicals Corporation HCH0007231 ETHYL 3-(2,5-DIFLUOROPHENYL)-3-OXOPROPANOATE 95.00% 887267-53-0 5G $909.56 2021-12-16 Buy
AK Scientific 4567AC Ethyl3-(2,5-difluorophenyl)-3-oxopropanoate 887267-53-0 5g $1063 2021-12-16 Buy
Product number Packaging Price Buy
E916705 500mg $285 Buy
2629-3-30 250mg $291 Buy
2629-3-30 1g $795 Buy
HCH0007231 5G $909.56 Buy
4567AC 5g $1063 Buy

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Chemical Properties,Uses,Production

Uses

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate is commonly utilized in organic synthesis as C-nucleophiles. One specific example is its reaction with the N-terminal electrophile CF3CHN2, resulting in the formation of CF3-heterocycles, namely ethyl 6-fluoro-4-oxo-1-(2,2,2-trifluoroethyl)-1,4-dihydrocinnoline-3-carboxylate[1].
Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate

References

[1] Arkhipov A, et al. Unexpected Reactivity of Trifluoromethyl Diazomethane (CF3CHN2): Electrophilicity of the Terminal N?Atom. Organic Letters, 2016; 18: 3406–3409.

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 56)Suppliers
Supplier Tel Email Country ProdList Advantage
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Aladdin Scientific
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Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 12357 58
ETHYL 3-(2,5-DIFLUOROPHENYL)-3-OXOPROPANOATE ETHYL 2,5-DIFLUOROBENZOYLACETATE 3-(2,5-Difluoro-phenyl)-3-oxo-propionic acid ethyl ester Ethyl 3-(2,5-difluorophenyl) 2-fluoro-3-(3-fluorophenyl)-3-oxopropanoic acid ethyl ester Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate 95+% Benzenepropanoic acid, 2,5-difluoro-β-oxo-, ethyl ester Ethyl 2,5-difluoro-β-oxobenzenepropanoate 887267-53-0