debrisoquine
- CAS No.
- 1131-64-2
- Chemical Name:
- debrisoquine
- Synonyms
- ebrisoquin;Debrisochin;Debrisoquin;debrisoquine;Isocaramidine;Debrisoquine Monomer;3,4-Dihydro-2(1H)-isoquinolinecarbimidamide;3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXAMIDINE;3,4-dihydro-1H-isoquinoline-2-carboximidamide;3,4-Dihydro-2(1H)-isoquinolinecarboximidamide
- CBNumber:
- CB3904530
- Molecular Formula:
- C10H13N3
- Molecular Weight:
- 175.23
- MDL Number:
- MOL File:
- 1131-64-2.mol
| Melting point | 278-280 °C |
|---|---|
| Boiling point | 309.8±52.0 °C(Predicted) |
| Density | 1.24±0.1 g/cm3(Predicted) |
| pka | pKa 11.9 (Uncertain) |
| FDA UNII | X31CDK040E |
| ATC code | C02CC04 |
debrisoquine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | D1814 | Debrisoquin | 1131-64-2 | 100mg | $425 | 2021-12-16 | Buy |
| TRC | B426748 | 3,4-Dihydroisoquinoline-2(1H)-carboximidamide | 1131-64-2 | 10mg | $45 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0000508 | DEBRISOQUINE 95.00% | 1131-64-2 | 5MG | $188.1 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0000508 | DEBRISOQUINE 95.00% | 1131-64-2 | 100MG | $697.34 | 2021-12-16 | Buy |
| AccelPharmtech | R2688 | 3,4-dihydro-2(1H)-Isoquinolinecarboximidamide 97.00% | 1131-64-2 | 1G | $1940 | 2021-12-16 | Buy |
debrisoquine Chemical Properties,Uses,Production
Originator
Declinax,Roche,UK,1967
Uses
Antihypertensive.
Definition
ChEBI: Debrisoquin is a member of isoquinolines and a carboxamidine. It has a role as an antihypertensive agent, an adrenergic agent, a sympatholytic agent and a human metabolite.
Manufacturing Process
27 g of 1,2,3,4-tetrahydroisoquinoline was added at room temperature to a
solution of 28 g of 2-methyl-2-isothiourea sulfate in 80 ml of water. The
resulting mixture was kept at room temperature with occasional shaking. After
a short period of time, methylmercaptan began to escape, and the mixture
warmed up slightly. After then standing for 24 hours, crystals formed. They
were filtered off and rinsed with ice cold water. Recrystallization from
approximately 100 ml of water yielded 1,2,3,4-tetrahydroisoquinoline-2-
carboxamidine sulfate melting at 278°C to 280°C (uncorr.).
Another batch prepared in the same manner melted at 284°C to 285°C due to
a minute difference in moisture content.
Both batches prepared above analyzed correctly for (C10H13N3)2·H2SO4.
brand name
Declinax (HoffmannLaRoche).
Therapeutic Function
Antihypertensive
debrisoquine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12990 | 57 | |
| Hubei Yangxin Medical Technology Co., Ltd. | 15374522761 | 3003392093@qq.com | China | 7851 | 55 |
| Hubei Xinyang Medical Technology Co., Ltd | 15347293736 15347293736 | 2853117764@qq.com | China | 8854 | 58 |
| Hubei Xinkang Pharmaceutical Chemical Co., Ltd | 027-027-59308705 18871579363 | 1248680011@qq.com | China | 9984 | 58 |
| Hebei Zhenjia new material Co., LTD | 0319-5925599 13315915972 | 13313090628@163.com | China | 3489 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 15229059051 | 1027@dideu.com | China | 9902 | 58 |
| Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd | 18502726233 | 3641133981@qq.com | China | 9220 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | -- | info@synzest.com | China | 6857 | 58 |
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