Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>MTP 131 acetate

MTP 131 acetate

MTP 131 acetate Structure
MTP 131 acetate structure
CAS No.
1334953-95-5
Chemical Name:
MTP 131 acetate
Synonyms
MTP 131 acetate
CBNumber:
CB39739359
Molecular Formula:
C34H53N9O7
Molecular Weight:
699.85
MDL Number:
MOL File:
1334953-95-5.mol
Last updated:2025-09-18 19:10:02
Request For Quotation

MTP 131 acetate Properties

storage temp. -20°C
solubility PBS (pH 7.2): 10 mg/ml
form A crystalline solid

MTP 131 acetate Chemical Properties,Uses,Production

Biological Activity

MTP 131 is a mitochondria-targeted peptide antioxidant.1,2 It localizes to the mitochondria and reduces tert-butyl hydroperoxide-induced lipid peroxidation and apoptosis in SH-SY5Y cells when used at concentrations ranging from 0.001 to 1 nM.1 MTP 131 (2 mg/kg) reduces infarct volume, hemispheric swelling, and glutathione (GSH) depletion in a mouse model of acute cerebral ischemia induced by middle cerebral artery occlusion (MCAO).2 It increases survival, improves motor function, and decreases degeneration of the lumbar spinal cord in a superoxide dismutase 1 mutant (SOD1G93A) transgenic mouse model of amyotrophic lateral sclerosis (ALS) when administered at a dose of 5 mg/kg. MTP 131 reduces albuminuria, urinary hydrogen peroxide levels, and mesangial matrix accumulation, as well as preserves superoxide production, in a db/db mouse model of diabetic nephropathy.3

References

1.Zhao, K., Luo, G., Giannelli, S., et al.Mitochondria-targeted peptide prevents mitochondrial depolarization and apoptosis induced by tert-butyl hydroperoxide in neuronal cell linesBiochem. Pharmacol.70(12)1796-1806(2005) 2.Szeto, H.H.Mitochondria-targeted peptide antioxidants: Novel neuroprotective agentsAAPS J.8(3)E521-E531(2006) 3.Miyamoto, S., Zhang, G., Hall, D., et al.Restoring mitochondrial superoxide levels with elamipretide (MTP-131) protects db/db mice against progression of diabetic kidney diseaseJ. Biol. Chem.295(21)7249-7260(2020)

MTP 131 acetate Preparation Products And Raw materials

Raw materials

Preparation Products

MTP 131 acetate Suppliers

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39035 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919 Eric@peptidego.com China 7408 58
ChemeGen 18818260767 2625930290@qq.com China 6973 58
InvivoChem 13549236410 sales@invivochem.cn China 6753 58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD 0571-87213919 17306812703 3007955328@qq.com China 6979 58
Tanmo Quality Inspection Technology Co., Ltd. 4008-099-669 23419001name@qq.com CHINA 6043 58
Sangon Biotech (Shanghai) Co.,Ltd. 400-821-026 Sales@sangon.com China 6710 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
Shanghai EFE Biological Technology Co., Ltd. 58
Hangzhou Peptidego Biotech Co.,Ltd. 58
ChemeGen 58
InvivoChem 58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD 58
Tanmo Quality Inspection Technology Co., Ltd. 58
Sangon Biotech (Shanghai) Co.,Ltd. 58

View Lastest Price from MTP 131 acetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
MTP 131 acetate pictures 2025-09-18 MTP 131 acetate
1334953-95-5
 US $0.00 / removed 99.90% 10g TargetMol Chemicals Inc.
  • MTP 131 acetate pictures
  • MTP 131 acetate
    1334953-95-5
  • US $0.00 / removed
  • 99.90%
  • TargetMol Chemicals Inc.

1334953-95-5(MTP 131 acetate)Related Search:

DALDA (BCH-150) N-TRICOSANOYLTRYPTAMINE Elamipretide MLCK INHIBITOR PEPTIDE 18 (R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-N-((R)-1-amino-1-oxo-3-phenylpropan-2-yl)-5-guanidinopentanamide
MTP 131 acetate 1334953-95-5