ChemicalBook >> CAS DataBase List >>5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
- CAS No.
- 1434-54-4
- Chemical Name:
- 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
- Synonyms
- pcn;sc4674;U-14975;16-alpha-cyanopregnenolone;pregnenolone-16α-carbonitrile;Pregnenolone 16α-carbonitrile;5-PREGNEN-16α-CYANO-3β-OL-20-ONE;PREGNENOLONE-16ALPHA-CARBONITRILE;16α-Cyano-3β-hydroxypregn-5-en-20-one;5-pregnen-3B-ol-20-one-16A-carbonitrile
- CBNumber:
- CB4150567
- Molecular Formula:
- C22H31NO2
- Molecular Weight:
- 341.49
- MDL Number:
- MFCD00079212
- MOL File:
- 1434-54-4.mol
Last updated:2023-05-04 17:34:33
| Melting point | 225-228 °C(Solv: methanol (67-56-1); benzene (71-43-2)) |
|---|---|
| Boiling point | 508.5±50.0 °C(Predicted) |
| Density | 1.13±0.1 g/cm3(Predicted) |
| Flash point | 93 °C |
| storage temp. | 2-8°C |
| solubility | Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml |
| form | White to off-white solid. |
| pka | 14.95±0.70(Predicted) |
| FDA UNII | BA9WH84QAJ |
| EPA Substance Registry System | Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3.beta.,16.alpha.)- (1434-54-4) |
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P0543 | 5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97% | 1434-54-4 | 50mg | $83.5 | 2024-03-01 | Buy |
| Sigma-Aldrich | P0543 | 5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97% | 1434-54-4 | 100mg | $150 | 2024-03-01 | Buy |
| Cayman Chemical | 16343 | Pregnenolone Carbonitrile ≥98% | 1434-54-4 | 25mg | $40 | 2024-03-01 | Buy |
| Cayman Chemical | 16343 | Pregnenolone Carbonitrile ≥98% | 1434-54-4 | 50mg | $64 | 2024-03-01 | Buy |
| Sigma-Aldrich | P0543 | 5-Pregnen-3β-ol-20-one-16α-carbonitrile ≥97% | 1434-54-4 | 250mg | $290 | 2024-03-01 | Buy |
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Chemical Properties,Uses,Production
Uses
Pregnenolone Carbonitrile is a glucocorticoid receptor antagonist that induces the expression of the CYP3A family of steroid hydroxylases and modulates sterol and bile acid biosynthesis in vivo. Pregnenolone Carbonitrile is an an activator of rat pregnane X receptor (PXR).
Definition
ChEBI: Pregnenolone 16alpha-carbonitrile is an aliphatic nitrile. It is functionally related to a pregnenolone.
Biochem/physiol Actions
Pregnenolone-16a-carbonitrile (PCN) is a glucocorticoid receptor antagonist and a PXR (pregnane X receptor) activator.
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Suppliers
Global( 33)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15878 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4587 | 58 |
| Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4381 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shanghai Puluokai Medical Technology Co., LTD | 17269768198 | prochemx@163.com | China | 613 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
1434-54-4(5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE)Related Search:
1of4
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
5-pregnen-3B-ol-20-one-16A-carbonitrile
(3S,8S,9S,10R,13S,14S,16R,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile
(3S,8S,9S,10R,13S,14S,16R,17S)-17-ethanoyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile
pregnenolone-16α-carbonitrile
16α-Cyano-3β-hydroxypregn-5-en-20-one
U-14975
16-alpha)-3-hydroxy-20-oxopregn-5-ene-16-carbonitrile(3-bet
16-alpha-cyanopregnenolone
3beta-hydroxy-20-oxo-pregn-5-ene-16-alpha-carbonitril
3-hydroxy-20-oxo-,(3-beta,16-alpha)-pregn-5-ene-16-carbonitril
pcn
sc4674
PREGNENOLONE-16ALPHA-CARBONITRILE
Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3β,16α)-
CYPs,Cytochrome P450,P4503A,orally,Pregnenolone Carbonitrile,Pregnenolone 16α-carbonitrile,Inhibitor,PXR,cytochrome,inhibit
5-PREGNEN-16α-CYANO-3β-OL-20-ONE
Pregnenolone 16α-carbonitrile
1434-54-4
C22H31NO2
BioChemical
Cell Signaling and Neuroscience
Cell Biology
Cytokines, Growth Factors and Hormones
Corticosterone
Hormones
Steroid Hormones