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ChemicalBook >> CAS DataBase List >>tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate

tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate

tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate Structure
tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate structure
CAS No.
923009-50-1
Chemical Name:
tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate
Synonyms
tert-Butyl 4-oxo-3,9-diazaspiro[4.5]decane-9-carboxylate;tert-butyl 1-oxo-2,9-diazaspiro[4.5]decane-9-carboxylate;tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate;tert-butyl 2-ethyl-1-oxo-2,7-diazaspiro[4.5]decane-7-carboxy...;tert-Butyl 4-oxo-3,9-diazaspiro[4.5]decane-9-carboxylate - B0957;1-Oxo-2,7-diazaspiro[4.5]decane-7-carboxylic acid tert-butyl ester;2,7-Diazaspiro[4.5]decane-7-carboxylic acid, 1-oxo-, 1,1-diMethylethyl ester
CBNumber:
CB42461069
Molecular Formula:
C13H22N2O3
Molecular Weight:
254.33
MDL Number:
MFCD11227060
MOL File:
923009-50-1.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:40
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tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate Properties

Boiling point 425℃
Density 1.15
Flash point 211℃
storage temp. 2-8°C
pka 15.97±0.20(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H303-H320
Precautionary statements  P312-P264-P305+P351+P338-P337+P313
HS Code  2933998090

tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth YLB00950 tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate 923009-50-1 2.5g $354 2026-06-05 Buy
Apolloscientific OR315435 tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate 98% 923009-50-1 100mg $47 2026-06-04 Buy
Apolloscientific OR315435 tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate 98% 923009-50-1 250mg $74 2026-06-04 Buy
Apolloscientific OR315435 tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate 98% 923009-50-1 1g $107 2026-06-04 Buy
Apolloscientific OR315435 tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate 98% 923009-50-1 5g $362 2026-06-04 Buy
Product number Packaging Price Buy
YLB00950 2.5g $354 Buy
OR315435 100mg $47 Buy
OR315435 250mg $74 Buy
OR315435 1g $107 Buy
OR315435 5g $362 Buy

tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate Chemical Properties, Uses, Production

Synthesis

Di-tert-butyl dicarbonate

24424-99-5

2,7-DIAZASPIRO[4.5]DECAN-1-ONE HYDROCHLORIDE

1187173-43-8

TERT-BUTYL 1-OXO-2,7-DIAZASPIRO[4.5]DECANE-7-CARBOXYLATE

923009-50-1

Preparation of Example 44: tert-butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate (P44) was synthesized as follows: 2,7-diazaspiro[4.5]decan-1-one hydrochloride (600 mg, 3.15 mmol) was dissolved in 30 mL of dichloromethane (DCM). To this solution, triethylamine (TEA, 1.98 mL, 14.18 mmol) and di-tert-butyl dicarbonate (Boc2O, 895 mg, 4.10 mmol) were added sequentially. The reaction mixture was stirred at room temperature for 4 hours. After completion of the reaction, it was quenched by addition of water and the organic and aqueous layers were separated. The organic layer was washed with aqueous ammonium chloride (NH4Cl), dried over anhydrous sodium sulfate, and concentrated under reduced pressure to remove the solvent to afford the target product tert-butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate (P44, 830 mg, quantitative yield) as a colorless oil. Mass spectrum (ESI) m/z: 255.2 [M + H]+.

References

[1] Patent: WO2016/42451, 2016, A1. Location in patent: Page/Page column 84

tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate synthesis

24424-99-5
1187173-43-8
923009-50-1
Synthesis of tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate from Di-tert-butyl dicarbonate and 2,7-Diazaspiro[4.5]decan-1-one hydrochloride

tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate Preparation Products And Raw materials

Raw materials

2,7-Diazaspiro[4.5]decan-1-one hydrochloride 1,3-Piperidinedicarboxylic acid, 3-(cyanomethyl)-, 1-(1,1-dimethylethyl) 3-ethyl ester Di-tert-butyl dicarbonate Dichloromethane Triethylamine

Preparation Products

tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate Suppliers

Global Suppliers ( 73)
Supplier Tel Email Country ProdList Advantage
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2915 55
Wuhan TCASChem Technology Co., Ltd. 027-86697669 13986148687 sales@tcaschem.com China 3999 55
Nanjing JinruiJiuAn Biotechnology Co., Ltd. 025-58196018 800028039 sales@fartop.net China 2227 55
Shanghai Run-Biotech Co., Ltd. 021-57171705 13817537615 sales@run-biotech.com China 2270 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai AQBioPharma Co., Ltd. 13661411401 yinglv.que@aqbiopharma.com.cn China 2976 58
Shanghai Tombiopharma Chemical Co. Ltd. 13391076197 tombiopharma@163.com China 4986 55
Shanghai XR Chemical Technology Co., Ltd. 021-31007982 18019432809; info@xrpharma.com China 686 55
Hangzhou Milestone Pharmtech Co., Ltd. 0571-82896630 18969958410 sales_hz@milestonepharmtech.com China 4909 55
Nanjing Chempioneer Pharmaceutical Co., Ltd. 18068075658 sales@chempioneer.com China 1803 58
Supplier Advantage
Shanghai Boyle Chemical Co., Ltd. 55
Wuhan TCASChem Technology Co., Ltd. 55
Nanjing JinruiJiuAn Biotechnology Co., Ltd. 55
Shanghai Run-Biotech Co., Ltd. 58
Bide Pharmatech Ltd. 60
Shanghai AQBioPharma Co., Ltd. 58
Shanghai Tombiopharma Chemical Co. Ltd. 55
Shanghai XR Chemical Technology Co., Ltd. 55
Hangzhou Milestone Pharmtech Co., Ltd. 55
Nanjing Chempioneer Pharmaceutical Co., Ltd. 58

View Latest Price from tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TERT-BUTYL 1-OXO-2,7-DIAZASPIRO[4.5]DECANE-7-CARBOXYLATE pictures 2020-03-08 TERT-BUTYL 1-OXO-2,7-DIAZASPIRO[4.5]DECANE-7-CARBOXYLATE
923009-50-1
 $3.00 1KG 99%min 200kg Career Henan Chemical Co

tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate Spectrum

TERT-BUTYL 1-OXO-2,7-DIAZASPIRO[4.5]DECANE-7-CARBOXYLATE(923009-50-1)1HNMRTERT-BUTYL 1-OXO-2,7-DIAZASPIRO[4.5]DECANE-7-CARBOXYLATE(923009-50-1)1HNMR

923009-50-1 (tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate) Related Search:

1-Oxa-4,8-diazaspiro[5.5]undecan-8-carboxylic acid tert-butyl ester 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate 3-Azabicyclo[3.1.0]hexane-3,6-dicarboxylic acid 3-tert-butyl ester 7-Boc-1,7-diaza-spiro[4.4]nonane Tert-butyl 2,6-diazaspiro[3.4]octane-6-carboxylate
Carbamic acid, 3-azabicyclo[3.1.0]hex-1-yl-, 1,1-dimethylethyl ester (9CI) Tert-butyl 1,7-diazaspiro[4,4]nonane-1-carboxylate Tert-butyl 2,6-diazaspiro[3.4]octane-2-carboxylate benzyl 5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate 2S-7-Aza-bicyclo[2.2.1]heptane-2,7-dicarboxylic acid 7-tert-butyl ester
4-Oxo-hexahydro-cyclopenta[c]pyrrole-2-carboxylic acid tert-butyl ester 7-(tert-Butoxycarbonyl)-1-oxa-2,7-diazaspiro[4.4]non-2-ene-3-carboxylic acid Bicyclo[2.2.2]octane-1,4-dicarboxylic acid hemimethyl ester tert-Butyl 3-fluoro-4-oxopiperidine-1-carboxylate 2-(3-(tert-Butoxycarbonyl)-3-azaspiro[5.5]undecan-9-yl)acetic acid
1-Benzyl-octahydro-pyrrolo[3,4-b]pyrrole tert-butyl 2-formylpropan-2-ylcarbamate H2N-PEG1-CH2COOtBu

1of4

2,7-Diazaspiro[4.5]decane-7-carboxylic acid, 1-oxo-, 1,1-diMethylethyl ester 1-Oxo-2,7-diazaspiro[4.5]decane-7-carboxylic acid tert-butyl ester tert-Butyl 4-oxo-3,9-diazaspiro[4.5]decane-9-carboxylate tert-Butyl 4-oxo-3,9-diazaspiro[4.5]decane-9-carboxylate - B0957 tert-butyl 1-oxo-2,9-diazaspiro[4.5]decane-9-carboxylate tert-butyl 2-ethyl-1-oxo-2,7-diazaspiro[4.5]decane-7-carboxy... tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate 923009-50-1