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Cinacalcet IMpurity 9

CAS No.
802918-36-1
Chemical Name:
Cinacalcet IMpurity 9
Synonyms
Cinacalcet-13;CicalcetDihydroImpurity2HCl;Cinacalcet Dihydro Impurity 2 HCl;(R)-N-(1-(5,6-dihydronaphthalen-1-yl)ethyl)-;N-[(1R)-1-(5,6-dihydronaphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine;(αR)-5,6-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine;1-Naphthalenemethanamine, 5,6-dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-, (αR)-;N-(1-(7,8-dihydrophthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-aminehydrochloride;(alphaR)-5,6-Dihydro-alpha-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine;Cinacalcet impurity 13/Cinacalcet Dihydro Impurity 2 HCl/(R)-N-(1-(5,6-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl) phenyl)propan-1-amine hydrochloride
CBNumber:
CB42673837
Molecular Formula:
C22H24F3N
Molecular Weight:
359.44
MDL Number:
MOL File:
802918-36-1.mol

Cinacalcet IMpurity 9 Properties

Boiling point 433.5±45.0 °C(Predicted)
Density 1.138±0.06 g/cm3(Predicted)
pka 9.46±0.29(Predicted)

Cinacalcet IMpurity 9 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D455335 (αR)-5,6-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine 802918-36-1 10mg $14025 2021-12-16 Buy
Product number Packaging Price Buy
D455335 10mg $14025 Buy

Cinacalcet IMpurity 9 Chemical Properties,Uses,Production

Uses

(αR)-5,6-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine is synthetically prepared though a double bond migration in Heck reaction during the preparation of cinacalcet congeners. This enantiomerically pure material is seperated from its counter part, (αR)-7,8-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine (D455330) using HPLC.

Cinacalcet IMpurity 9 Preparation Products And Raw materials

Raw materials

Preparation Products

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(αR)-5,6-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine Cinacalcet impurity 13/Cinacalcet Dihydro Impurity 2 HCl/(R)-N-(1-(5,6-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl) phenyl)propan-1-amine hydrochloride Cinacalcet-13 (R)-N-(1-(5,6-dihydronaphthalen-1-yl)ethyl)- N-[(1R)-1-(5,6-dihydronaphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine N-(1-(7,8-dihydrophthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-aminehydrochloride Cinacalcet Dihydro Impurity 2 HCl 1-Naphthalenemethanamine, 5,6-dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-, (αR)- CicalcetDihydroImpurity2HCl (alphaR)-5,6-Dihydro-alpha-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine 802918-36-1