GerMicidin A
- CAS No.
- 150973-78-7
- Chemical Name:
- GerMicidin A
- Synonyms
- GerMicidin A;2H-Pyran-2-one, 3-ethyl-4-hydroxy-6-(1-methylethyl)-
- CBNumber:
- CB42703734
- Molecular Formula:
- C10H14O3
- Molecular Weight:
- 182.22
- MDL Number:
- MOL File:
- 150973-78-7.mol
GerMicidin A price More Price(11)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 20591 | Germicidin B ≥95% | 150973-78-7 | 500 μg | $175 | 2024-03-01 | Buy |
Cayman Chemical | 19971 | Germicidin A ≥95% | 150973-78-7 | 1mg | $220 | 2024-03-01 | Buy |
Cayman Chemical | 19971 | Germicidin A ≥95% | 150973-78-7 | 5mg | $984 | 2024-03-01 | Buy |
Cayman Chemical | 20591 | Germicidin B ≥95% | 150973-78-7 | 1mg | $205 | 2022-04-27 | Buy |
Cayman Chemical | 20591 | Germicidin B ≥95% | 150973-78-7 | 5mg | $946 | 2022-04-27 | Buy |
GerMicidin A Chemical Properties,Uses,Production
Description
Germicidin A is a pyranone originally derived from S. viridochromogenes that acts as a reversible, autoregulative inhibitor of spore germination and hyphal elongation in the genus Streptomyces at concentrations as low as 200 pM. During germination, spores of Streptomyces excrete germicidin A along with other germicidin homologs, which inhibit germination of its own arthrospores. At higher concentrations, germicidin A can inhibit the porcine Na+/K+-activated ATPase (ID50 = 100 μM) and prevent the germination of the cress L. sativum.
Uses
Germicidin A is an extremely potent autoregulator.
Uses
Germicidin A is a pyranone isolated from Streptomyces sp. in 1993. Germicidin A is an extremely potent autoregulator of the sporulation of the producing strain, and spores of closely related species. Inhibition is detected at 0.1 ng/ml and is orders of magnitude more potent than a diverse range of antibiotics.
References
[1] petersen f, zhner h, metzger j w, et al. germicidin, an autoregulative germination inhibitor of streptomyces viridochromogenes nrrl b-1551[j]. the journal of antibiotics, 1993, 46(7): 1126-1138.
[2] aoki y, matsumoto d, kawaide h, et al. physiological role of germicidins in spore germination and hyphal elongation in streptomyces coelicolor a3 (2)[j]. the journal of antibiotics, 2011, 64(9): 607-611.
GerMicidin A Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 17993 | 56 |
Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4587 | 58 |
Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4381 | 58 |
Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 56039 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
Meng Cheng Technology (Shanghai) Co., LTD | 400-820-6829 | sales@mitachieve.com | China | 8864 | 58 |
Zhejiang Huida Biotech Co., LTD | 0571-89903882 13626641628 | jiangnan@huidabiotech.com | China | 3656 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |