ChemicalBook >> CAS DataBase List >>N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE structure

CAS No.: 132172-61-3

Chemical Name:: N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE

Synonyms: DOTAP;DOTMA;dotap chloride;1,2-dioleoyl-3-trimethylammonium-propane (chloride salt);NSC8484;NSC 8484;NSC-8484;DOTAP-Cl;Lipofectin;18:1 TAP (DOTAP)

CBNumber:: CB4441795

Molecular Formula:: C42H80ClNO4

Molecular Weight:: 698.56

MDL Number:: MFCD01310872

MOL File:: 132172-61-3.mol

MSDS File:: SDS

Last updated:2023-09-05 10:22:03

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N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE Properties

Melting point	35-38°C
storage temp.	-20°C
solubility	Chloroform (Slightly)
form	lyophilized powder
color	White to Pale Yellow
Stability	Store in Freezer, Hygroscopic
InChIKey	KSXTUUUQYQYKCR-LQDDAWAPSA-M
SMILES	C(C[N+](C)(C)C)(COC(=O)CCCCCCC/C=C\CCCCCCCC)OC(=O)CCCCCCC/C=C\CCCCCCCC.[Cl-]
FDA UNII	3R78UC794Z

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06,GHS08
Signal word	Danger
Hazard statements	H302-H315-H319-H331-H336-H351-H361d-H372-H412
Precautionary statements	P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313
WGK Germany	3

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	D6182	DOTAP chloride ≥98% (TLC), powder	132172-61-3	50mg	$463	2024-03-01	Buy
Sigma-Aldrich	D6182	DOTAP chloride ≥98% (TLC), powder	132172-61-3	250mg	$1840	2024-03-01	Buy
Cayman Chemical	15110	1,2-Dioleoyl-3-trimethylammoniumpropane (chloride) ≥95%	132172-61-3	50mg	$73	2024-03-01	Buy
Cayman Chemical	15110	1,2-Dioleoyl-3-trimethylammoniumpropane (chloride) ≥95%	132172-61-3	100mg	$138	2024-03-01	Buy
Cayman Chemical	15110	1,2-Dioleoyl-3-trimethylammoniumpropane (chloride) ≥95%	132172-61-3	250mg	$288	2024-03-01	Buy

Product number	Packaging	Price	Buy
D6182	50mg	$463	Buy
D6182	250mg	$1840	Buy
15110	50mg	$73	Buy
15110	100mg	$138	Buy
15110	250mg	$288	Buy

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE Chemical Properties,Uses,Production

Description

DOTAP chloride (1,2-Dioleoyl-3-trimethylammonium-propane chloride) is a potent cationic lipid widely used as a liposomal transfection reagent. DOTAP is also a strong activator of the innate immune system in animal cells and could serve as a potential candidate for the study of elicitors of plant immunity.

Description

DOTAP, 1,2-Dioleoyl-3-trimethylammonium propane is a di-chain, or gemini, cationic surfactant. DOTAP has been used for in vitro and in vivo nucleic acid and protein delivery.

Chemical Properties

White Foam

Uses

1,2-dioleoyloxy-3-(trimethylammonium)propane (DOTAP) chloride has been used for the preparation of cationic liposome and liposome-DNA complex. It has also been used to assess tumor necrosis factor α (TNF- α) production.

Uses

Small unilamellar liposomes containing DOTMA interact spontaneously with DNA to form lipid-DNA complexes with 100% entrapment of DNA. Facilitates fusion of the complex with the plasma membrane of tissue culture cells, resulting in both uptake and

Biochem/physiol Actions

18:1 TAP (DOTAP) is a cationic lipid structure, used for in vitro and in vivo nucleic acid and protein delivery. The lipid composition and cell type affects the transfection potential of DOTAP(1,2-dioleoyl-3-trimethylammonium-propane). 18:1 TAP (DOTAP) mediates gene knockdown technique in hematopoietic stem cells (HSCs).

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE Suppliers

Global( 134)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	6992	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5909	58
Shochem(Shanghai) Co.,Ltd	86-21-50800795	info@shochem.com	CHINA	288	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	12468	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58

Supplier	Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
BOC Sciences	58
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
Jinan Carbotang Biotech Co.,Ltd.	58
Shandong chuangyingchemical Co., Ltd.	58
Shochem(Shanghai) Co.,Ltd	58
Zhengzhou Alfa Chemical Co.,Ltd	58
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58

View Lastest Price from N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2021-07-13	N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE 132172-61-3	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2021-07-09	N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE 132172-61-3	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2020-07-27	DOTAP chloride 132172-61-3	US $0.00-0.00 / g	1g	98%MIN	5KG/MONTH	Shochem(Shanghai) Co.,Ltd

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE
132172-61-3
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE
132172-61-3
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

DOTAP chloride
132172-61-3
US $0.00-0.00 / g
98%MIN
Shochem(Shanghai) Co.,Ltd

132172-61-3(N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE)Related Search:

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DODMA DOTAP Ammonium chloride DOTAP MESYLATE, 98 N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE,N-[1-(2,3-DIOLEOYLOXY) PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE,DOTAP CHLORIDE SALT,DOTAP

DOTAP DOTAP methyl sulfate,DOTAP,DOTAP METHOSULFATE DOTAP MESYLATE DOTAP METHYL SULPHATE SALT DOTAP

DOTAP(OH) MESYLATE DOTAP acetate DOTAP(OH)2 MESYLATE

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1,2-DIOLEOYL-3-TRIMETHYLAMMONIUM-PROPANE, CHLORIDE DOTAP CHLORIDE SALT N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE N-[1-(2,3-DIOLEOYLOXY)PROPYL]-N,N,N-TRIMETHYL-AMMONIUM CHLORIDE SALT N-[1-(2,3-DIOLEOYLOXY) PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE TRIMETHYL[2,3-(DIOLEYLOXY)PROPYL]AMMONIUM CHLORIDE 2,3-Bis(oleoyloxy)-N,N,N-trimethyl-1-propanaminium 3-(Trimethylaminio)propane-1,2-diol 1,2-bis[(Z)-9-octadecenoate] Lipofectin N-[2,3-Bis(oleoyloxy)propyl]-N,N-dimethylmethanaminium N-[2,3-Di(oleoyloxy)propyl]-N,N,N-trimethylaminium N,N,N-TriMethyl-2,3-bis[[(9Z)-1-oxo-9-octadecenyl]oxy]-1-propanaMiniuM DOTAP;DOTAP, CHLORIDE 18:1 TAP (DOTAP) 2,3-di(octadec-9-enoyloxy)propyl-trimethylazanium (2，3-Dioleyl-propyl) -trimethylamine N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium chloride 1-Propanaminium, N,N,N-trimethyl-2,3-bis[[(9Z)-1-oxo-9-octadecenyl]oxy]-, chloride (1:1) NSC 8484 NSC8484 NSC-8484 DOTMA DOTAP dotap chloride 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) DOTAP-Cl 132172-61-3 C42H80ClNO4 C40H80ClNO2 Ammonium Chlorides (Quaternary) Quaternary Ammonium Compounds BioChemical Cloning and Expression Molecular Biology Transfection & Transformation Fatty Acid Derivatives & Lipids Glycerols Mixed Fatty Acids