ChemicalBook >> CAS DataBase List >>Remibrutinib
Remibrutinib
- CAS No.
- 1787294-07-8
- Chemical Name:
- Remibrutinib
- Synonyms
- LOU064;LOU-064;REMIBRUTINIB;Remibrutinib (LOU064);Btk,Inhibitor,inhibit,Remibrutinib,Bruton tyrosine kinase;N-(3-(6-Amino-5-(2-(N-methylacrylamido)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphenyl)-4-cyclopropyl-2-fluorobenzamide;N-(3-{5-[2-(Acryloyl-methyl-amino)-ethoxy]-6-amino-pyrimidin-4-yl}-5-fluoro-2-methyl-phenyl)-4-cyclopropyl-2-fluoro-benzamide;N-[3-[6-Amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluorobenzamide;Benzamide, N-[3-[6-amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluoro-
- CBNumber:
- CB44675356
- Molecular Formula:
- C27H27F2N5O3
- Molecular Weight:
- 507.53
- MDL Number:
- MFCD32215329
- MOL File:
- 1787294-07-8.mol
Last updated:2023-09-20 16:43:00
| Boiling point | 634.8±55.0 °C(Predicted) |
|---|---|
| Density | 1.332±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: 125 mg/mL (246.29 mM) |
| pka | 11.67±0.70(Predicted) |
| FDA UNII | I7MVZ8HDNU |
Remibrutinib price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0103905 | Remibrutinib 99.26% | 1787294-07-8 | 5mg | $350 | 2021-12-16 | Buy |
| ChemScene | CS-0103905 | Remibrutinib 99.26% | 1787294-07-8 | 10mg | $550 | 2021-12-16 | Buy |
| ChemScene | CS-0103905 | Remibrutinib 99.26% | 1787294-07-8 | 50mg | $1650 | 2021-12-16 | Buy |
| ChemScene | CS-0103905 | Remibrutinib 99.26% | 1787294-07-8 | 100mg | $2250 | 2021-12-16 | Buy |
Remibrutinib Chemical Properties,Uses,Production
Description
Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib has the potential for Chronic urticaria (CU) treatment.
Chemical Properties
White to off-white Solid
Remibrutinib Preparation Products And Raw materials
Raw materials
Preparation Products
Remibrutinib Suppliers
Global( 45)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Suzhou ARTK Medchem Co., Ltd. | +8618168183658 | sales1@artkmedchem.com | China | 39009 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 4692 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 4300 | 58 |
| Shanghai XingMo Biotechnology Co., Ltd. | 13524779951 | 2075692521@qq.com | China | 310 | 55 |
| Shanghai Hope Chem Co., Ltd.， | +21-18501659228 18501659228 | info@hope-chem.com | China | 438 | 55 |
| Bayee Biotech (Anqing) Co., Ltd. | 0556-0556-5032306 18917961636 | wtx@bayeebio.com | China | 253 | 61 |
Remibrutinib (LOU064)
LOU064
LOU-064
REMIBRUTINIB
N-(3-{5-[2-(Acryloyl-methyl-amino)-ethoxy]-6-amino-pyrimidin-4-yl}-5-fluoro-2-methyl-phenyl)-4-cyclopropyl-2-fluoro-benzamide
Benzamide, N-[3-[6-amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluoro-
N-(3-(6-Amino-5-(2-(N-methylacrylamido)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphenyl)-4-cyclopropyl-2-fluorobenzamide
Btk,Inhibitor,inhibit,Remibrutinib,Bruton tyrosine kinase
N-[3-[6-Amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluorobenzamide
1787294-07-8
C27H27F2N5O3