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PROTAC ERRα Degrader-2

PROTAC ERRα Degrader-2 Structure
PROTAC ERRα Degrader-2 structure
CAS No.
2306388-85-0
Chemical Name:
PROTAC ERRα Degrader-2
Synonyms
PROTAC ERRα Degrader-2;PROTAC ERRα Degrader-2;1-Piperazineacetamide, 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-N-[5-[[(2E)-3-[4-[[2,4-bis(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]-2-cyano-1-oxo-2-propen-1-yl]amino]pentyl]-2-oxo-
CBNumber:
CB48054809
Molecular Formula:
C57H55Cl2F6N7O8
Molecular Weight:
1150.99
MDL Number:
MFCD32197287
MOL File:
2306388-85-0.mol
Last updated:2023-05-21 10:59:17
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PROTAC ERRα Degrader-2 Properties

Density 1.35±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 12.45±0.46(Predicted)

PROTAC ERRα Degrader-2 Chemical Properties,Uses,Production

Description

PROTAC ERRalpha Degrader-2 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRalpha Degrader-2 is an estrogen-related receptor alpha (ERRa) degrader[1].

References

[1]. Peng L, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10(5):767-772.

PROTAC ERRα Degrader-2 Preparation Products And Raw materials

Raw materials

Preparation Products

PROTAC ERRα Degrader-2 Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7892 56
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9445 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1290 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223 psaitong@jm-bio.com China 29834 58
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822 czbjpharma@126.com China 18488 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Sichuan Wei Keqi Biological Technology Co., Ltd. 56
Shanghai Chaolan Chemical Technology Center 58
Jilin Province Woda Biotechnology Co., Ltd. 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Changzhou Bojia Biomedical Technology Co., Ltd. 58

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PROTAC ERRα Degrader-2 PROTAC ERRα Degrader-2 1-Piperazineacetamide, 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-N-[5-[[(2E)-3-[4-[[2,4-bis(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]-2-cyano-1-oxo-2-propen-1-yl]amino]pentyl]-2-oxo- 2306388-85-0