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PROTAC CRBN Degrader-1

PROTAC CRBN Degrader-1 structure

CAS No.: 2358775-70-7

Chemical Name:: PROTAC CRBN Degrader-1

Synonyms: CRBN PROTAC?14a;PROTAC CRBN Degrader-1;N1-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)-N20-((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-3,9,12,18-tetraoxaicosane-1,20-diamide

CBNumber:: CB88054807

Molecular Formula:: C53H72N8O13S

Molecular Weight:: 1061.25

MDL Number:: MFCD32197292

MOL File:: Mol file

Last updated:2023-06-30 15:45:59

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PROTAC CRBN Degrader-1 Properties

Boiling point	1241.2±65.0 °C(Predicted)
Density	1.294±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO: 200 mg/mL (188.46 mM)
pka	10.74±0.40(Predicted)

PROTAC CRBN Degrader-1 Chemical Properties,Uses,Production

Description

CRBN PROTAC? 14a is a cereblon degrader. It comprises a ligand for Von Hippel Lindau (VHL) protein joined by a linker to a cereblon targeting ligand. It preferentially degrades cereblon, and induces rapid and profound cereblon degradation.

storage

Store at -20°C

PROTAC CRBN Degrader-1 Preparation Products And Raw materials

Raw materials

Preparation Products

PROTAC CRBN Degrader-1 Suppliers

Global( 9)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	028-81700200 18116577057	3003855609@qq.com	China	7892	56
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9445	58
Jilin Province Woda Biotechnology Co., Ltd.	13504435624	1927928688@qq.com	China	1290	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Changzhou Bojia Biomedical Technology Co., Ltd.	2122619822	czbjpharma@126.com	China	18488	58
Suzhou origin Specialty Chemicals Co., Ltd	17701559125	jiaoshangjun@origsc.com	China	1785	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	4030	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	56
Shanghai Chaolan Chemical Technology Center	58
Jilin Province Woda Biotechnology Co., Ltd.	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
Changzhou Bojia Biomedical Technology Co., Ltd.	58
Suzhou origin Specialty Chemicals Co., Ltd	58
Nantong QuanYi Biotechnology Co., Ltd	58

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PROTAC CRBN Degrader-1 CRBN PROTAC?14a N1-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)-N20-((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-3,9,12,18-tetraoxaicosane-1,20-diamide 2358775-70-7