pipazetate hydrochloride
- CAS No.
- 6056-11-7
- Chemical Name:
- pipazetate hydrochloride
- Synonyms
- Selgon;Lenopect;Selvigon;Selvjgon;Pipazetate HCl;Theratuss Hydrochloride;pipazetate hydrochloride;Pipazethate hydrochloride;FEUBUXUFKHXRKO-UHFFFAOYSA-N;Pipazethate Monohydrochloride
- CBNumber:
- CB4875480
- Molecular Formula:
- C21H25N3O3S.ClH
- Molecular Weight:
- 435.973
- MDL Number:
- MOL File:
- 6056-11-7.mol
| Melting point | 160-161° |
|---|---|
| FDA UNII | 757GN3W2CZ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H315-H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362 |
| Toxicity | LD50 orally in rats: 560 mg/kg (Schuler) |
pipazetate hydrochloride price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | P475700 | PipazetateHydrochloride | 6056-11-7 | 10mg | $165 | 2021-12-16 | Buy |
| Usbiological | 019745 | Pipazetate Hydrochloride | 6056-11-7 | 10mg | $460 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 52790 | PipazetateHCl | 6056-11-7 | 10mg | $650 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0016766 | PIPAZETHATE HYDROCHLORIDE 95.00% | 6056-11-7 | 10MG | $329.7 | 2021-12-16 | Buy |
pipazetate hydrochloride Chemical Properties,Uses,Production
Originator
Theratuss, Squibb ,US ,1962
Uses
Pipazetate Hydrochloride, a pyridobenzothiazine derivative an antiarrhythmic characteristics. Pipazetate is used as a cough supressant.
Manufacturing Process
8.5 parts of 1-azaphenothiazine carboxylic acid chloride and 14 parts of piperidino-ethoxyethanol were introduced into 100 parts of chlorobenzene and the mixture boiled under reflux for 5 minutes. After cooling off the precipitated hydrochloride salt of piperidino-ethoxyethanol was filtered off on a suction filter. Water was added to the filtrate and the pH thereof adjusted to 5 to 6 with dilute HCl. The aqueous phase was then removed, a caustic soda solution added thereto and then extracted with ether. The ethyl extract was washed with water, then dried with potash and the ether distilled off. 9.4 parts of the piperidino-ethoxy-ethyl ester of 1-azaphenothiazine carboxylic acid were obtained. This product was dissolved in 20 parts of isopropanol and the solution neutralized with isopropanolic HCl. The monohydrochloride which precipitated out after recrystallization from isopropanol had a melting point of 160°C to 161°C.
Therapeutic Function
Antitussive
pipazetate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9702 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| Finetech Industry Limited | 027-87465837 19945049750 | sales@finetechnology-ind.com | China | 9664 | 58 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |