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LAVENDUSTIN C

CAS No.
125697-93-0
Chemical Name:
LAVENDUSTIN C
Synonyms
HDBA;NSC 666251;COMPOUND 5;LAVENDUSTIN C;Lavendustin C (HDBA);5-(2,5-DIHYDROXYBENZYLAMINO)SALICYLIC ACID;5-(N-2,5-DIHYDROXYBENZYL)AMINOSALICYLIC ACID;5-(N-2',5'-DIHYDROXYBENZYL)AMINOSALICYLIC ACID;N-(2',5'-DIHYDROXYBENZYL)-5-AMINOSALICYLIC ACID;2-hydroxy-5-(2,5-dihydrobenzyl)aminobenzoic acid
CBNumber:
CB5135705
Molecular Formula:
C14H13NO5
Molecular Weight:
275.26
MDL Number:
MFCD00153955
MOL File:
125697-93-0.mol
MSDS File:
SDS
Last updated:2023-09-20 16:43:00

LAVENDUSTIN C Properties

Melting point 193-195°C dec.
Boiling point 597.5±50.0 °C(Predicted)
Density 1.551±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO: soluble
form solid
pka 2.32±0.10(Predicted)
color Light Beige to Brown
Stability Hygroscopic
FDA UNII HJM06BIW5M

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H335-H319-H315
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
3-10
NFPA 704
0
2 0

LAVENDUSTIN C price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10010329 Lavendustin C ≥98% 125697-93-0 1mg $26 2024-03-01 Buy
Cayman Chemical 10010329 Lavendustin C ≥98% 125697-93-0 5mg $111 2024-03-01 Buy
Cayman Chemical 10010329 Lavendustin C ≥98% 125697-93-0 10mg $195 2024-03-01 Buy
Cayman Chemical 10010329 Lavendustin C ≥98% 125697-93-0 50mg $849 2024-03-01 Buy
TRC D452000 5-(2,5-Dihydroxybenzylamino)-2-hydroxybenzoicAcid 125697-93-0 25mg $410 2021-12-16 Buy
Product number Packaging Price Buy
10010329 1mg $26 Buy
10010329 5mg $111 Buy
10010329 10mg $195 Buy
10010329 50mg $849 Buy
D452000 25mg $410 Buy

LAVENDUSTIN C Chemical Properties,Uses,Production

Description

Lavendustin C, a derivative of a Streptomyces griseolavendus butyl acetate extract, is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase with an IC50 value of 0.012 μM. Lavendustin C also inhibits pp60c-src(+) kinase and Ca2+ calmodulin-dependent kinase II with IC50 values of 0.5 and 0.2 μM, respectively. At a concentration of 10-150 μM, lavendustin C inhibits tyrosine kinase-associated neutrophil degranulation and superoxide generation.

Chemical Properties

Brown Solid

Uses

Shows potent tyrosine kinase inhibitory activity.

Definition

ChEBI: 5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzoic acid is an aromatic amine.

LAVENDUSTIN C Preparation Products And Raw materials

Raw materials

Preparation Products

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ATK CHEMICAL COMPANY LIMITED
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LAVENDUSTIN C Spectrum

2-hydroxy-5-(2,5-dihydrobenzyl)aminobenzoic acid Compound 5, HDBA, N-(2μ,5μ-Dihydroxybenzyl)-5-aminosalicylic acid, [2-Hydroxy-5-[N-(2μ,5μ-dihydroxybenzyl)amino]benzoic acid 5-(2,5-Dihydroxybenzylamino)salicylic acid, N-(2,5-Dihydroxybenzyl)-5-aminosalicylic acid 5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzoic acid 5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxy-benzoic acid NSC 666251 2-HYDROXY-5-(2,5-DIHYDROXYBENZYLAMINO)BENZOIC ACID [2-HYDROXY-5-[N-(2',5'-DIHYDROXYBENZYL)AMINO]BENZOIC ACID 5-(2,5-DIHYDROXYBENZYLAMINO)-2-HYDROXYBENZOIC ACID 5-(2,5-DIHYDROXYBENZYLAMINO)SALICYLIC ACID 5-(N-2',5'-DIHYDROXYBENZYL)AMINOSALICYLIC ACID 5-(N-2,5-DIHYDROXYBENZYL)AMINOSALICYLIC ACID HDBA COMPOUND 5 LAVENDUSTIN C N-(2',5'-DIHYDROXYBENZYL)-5-AMINOSALICYLIC ACID Benzoic acid, 5-[[(2,5-dihydroxyphenyl)methyl]amino]-2-hydroxy- Lavendustin C (HDBA) N-(2-((2-((4Z,7Z,10Z,13Z,16Z,19Z)-DOCOSA-4,7,10,13,16,19-HEXAENAMIDO)ETHYL)DISULFANYL)-2-METHYLPROPYL)NICOTINAMIDE HER1,ErbB-1,EGFR,inhibit,Inhibitor,Calmodulin-dependent protein kinases,calmodulin-dependent,Src,lavendustin C,pp60,CaMK,Ca2+,Epidermal growth factor receptor,tyrosine,kinase,Calmodulin-dependent kinases 125697-93-0 Chelators Cell Signaling and Neuroscience Receptor Tyrosine Kinase Inhibitors Tyrosine Kinase (TK) Kinase/Phosphatase Biology Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Type Enzyme Inhibitors Cell Biology BioChemical Biochemicals and Reagents Other enzyme inhibitors and activators All Inhibitors Inhibitors Tyrosine Kinase Inhibitors